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251 articles for “tissue”
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Soft Tissue Cephalometric Norms of Various Ethnic Groups in North India: A Systematic Review
Abstract: Facial features play a key role in determining the esthetic attractiveness of a person. Cephalometric analysis paves way to have a guide to plan a treatment to bring aesthetically pleasing results. Soft tissue cephalometric analysis is helpful as guides while planning orthodontic, surgical, aesthetic procedures. However, since earliest cephalometric analysis are based solely on studies done on Caucasian population some key features may not be quite appealing while the results …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 1–4 Read article
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Expression Profiling of Immunomodulatory Genes in Canine Adipose Tissue–Derived Mesenchymal Stem Cells
Abstract: Adipose tissue–derived mesenchymal stem cells (AT-MSC) represent a heterogeneous population of self-renewing, multipotent progenitor cells residing in the stromal compartment of adipose tissue. Canine adipose tissue-derived mesenchymal stem cells have attracted significant interest in regenerative medicine due to their therapeutic potential in naturally occurring canine diseases and their translational relevance to human medicine. In the present study, canine adipose tissue–derived MSCs (cAT-MSCs) were isolated and differentiated into osteogenic, chondrogenic and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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In vivo Modulatory Effect of Clerodendrum Splendens (Glory Blossom) in Aluminum Induced Alzheimer Diseases and Lonchocarpus Sericeus in Rotenone Induced Parkinson’s Disease on Na+/K+ Atpase (Sodium Pump) in the Cerebral Tissues of Male Albino Wister Rats
Abstract: Elegant research has shown that plants are useful for both curative and preventive purpose on the humans populous. Prevalent among diseases associated with humans are neurological diseases which affect a large sector of the population especially the elderly. The most common neurological diseases are Parkinson and Alzheimer disease which affect a large sector of the brain and also cause an imbalance in brain electrolyte. Among such electrolytic mechanisms of the …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 31–36 Read article
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Exploring Recent Advancements in Nanomedicine for Tumor Microenvironmental Tissue Engineering
Abstract: The combination of tissue engineering and nanomedicine is transforming cancer treatment by offering creative ways to get around problems with conventional therapies. Recent developments in nanomedicine are examined in this review, with an emphasis on how they might be used to comprehend and control the tumor microenvironment (TME), a dynamic and complex environment that has a major impact on the course of cancer and the effectiveness of treatment. Targeted interactions …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 122–136 Read article
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Recent Advancements in Nanobiocomposite-Based Wound Healing and Tissue Regeneration
Abstract: Haemostasis, inflammation, proliferation, remodeling, and other highly coordinated cellular and molecular activities are all part of the complex biological processes of wound healing and tissue regeneration. Following an injury, these stages cooperate to restore tissue integrity and function. However, this normal process is disturbed in many clinical circumstances, especially chronic wounds such diabetic ulcers, burns, and pressure sores. Prolonged inflammation, chronic microbial infection, diminished angiogenesis, and impaired extracellular matrix production …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–318 Read article
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Examining Connective Tissue Changes Across Various Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Histochemical Polymeric Investigation
Abstract: Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) represent a spectrum of potentially malignant disorders posing significant challenges in diagnosis and management. The tumor microenvironment, particularly alterations in the connective tissue, plays a crucial role in the progression of these lesions. This histochemical investigation comprised with embedded polymers aimed to examine connective tissue changes across various grades of oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 124–137 Read article
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Reconstruction of broad soft tissue defect around knee with combined perforator flaps
Abstract: Perforator flaps have been commonly used in reconstruction of soft tissue defects nowadays; however, it is very important to apply them properly according to the characteristics of recipient site. Since there is no universal flap appropriate to various types of defects, there have been a number of research to apply appropriate perforator flaps suitable to recipient sites. Recently, achievements have been made by applying chimeric flaps based on perforators from …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 Read article
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Phytochemicals from Plectranthus amboinicus and Azadirachta indica for Promoting Angiogenesis and Tissue Regeneration – A Short Review
Abstract: The eco-friendly synthesis of silver nanoparticles (AgNPs) using plant extracts has garnered significant attention due to its potential in biomedical applications. This review highlights the green synthesis methodologies, focusing on Plectranthus amboinicus and Azadirachta indica, their phytochemical components, and their docking studies with angiogenesis-related receptors such as VEGF and FGF. The applications of AgNPs in tissue regeneration, wound healing, and angiogenesis are discussed in detail, emphasizing the roles of phytochemicals …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 34–40 Read article
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Evaluation and Fabrication of 3D Printed Bioactive β-TCP/PCL Scaffolds for Bone Tissue Engineering
Abstract: Bone is one of the tissue types that is transplanted the most worldwide. Each year, there are over four million procedures that incorporate the use of bone grafts or substitutes to help heal bone deficiencies. These treatments are still limited greatly, and there is always a demand to help because of trauma, cancer, infection, and arthritis. Because of this, researchers are targeting improvement in developing bioactive three-dimensional (3D) scaffolds that …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Light-Dark Cycle Disruption in Hypothalamus Tissue of Mus Musculus Causes Change in the Expression of Gm45928 Gene
Abstract: The majority of organisms on earth display consistent 24-hour rhythms in their physiology and behavior due to circadian biology. Light and dark cycles play a key role in setting our internal body clock, which controls things like our sleep patterns, hormone levels, body temperature, and metabolism. The disruption of the light-dark cycle has significant effects on the molecular and behavioral rhythms of the circadian clock of hypothalamus. Gm45928 is a …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 32–46 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Assessment of Decellularization Techniques for Fabrication of Tubular Submucosal Scaffolds from Small Intestine for Application in Oesophageal Tissue Engineering
Abstract: In this ground-breaking study, we sought to create superior tubular scaffolds for tissue engineering by utilizing small intestine submucosa (SIS), a remarkable biomaterial with outstanding therapeutic potential. We investigated two standard detergent-perfusion procedures, peracetic acid under perfusion and classic peracetic acid-agitation, to decellularize tubular SIS, with the goal of generating scaffolds with consistent and reliable properties for oesophageal tissue engineering. To assess biocompatibility, we employed metabolic research, microscopy, mechanical tests, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 30–38 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Effect of Nano-Prepared N. sativa Seed Extract on Cardiac Tissue Structure in Tartrazine-Treated Male Albino Mice
Abstract: This study investigates the effects of Tartrazine and N. sativa nanoparticles on body weight and cardiac histology in male albino mice. Thirty-six male mice were divided into four groups: a control group receiving physiological saline, a group treated with Tartrazine (20 mg/kg), a group receiving both Tartrazine and N. sativa nanoparticles (100 mg/kg), and a group treated solely with N. sativa nanoparticles (100 mg/kg). The body weights were chronicled before …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 119–124 Read article
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Image-Based Evaluation of Implant Tissue Interface Integrity in Polymer Orthopaedic Devices
Abstract: Polymer orthopedic implants offer radiolucency and mechanical compatibility with bone, but long-term success depends on maintaining a stable implant–tissue interface. Routine imaging is widely available for follow-up, yet interface integrity is commonly judged qualitatively, limiting early detection of fixation compromise and reducing comparability across devices and time points. This work presents an image-based methodology to quantify interface integrity by extracting interpretable interface descriptors from a standardized interface belt around the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 170–179 Read article
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Advances in Biopolymer-Based Surgical Implants: A Polymer Chemistry Perspective
Abstract: Biopolymers have emerged as a promising class of materials for surgical implants due to their biocompatibility, biodegradability, and ability to mimic natural tissue properties. These materials play a crucial role in modern biomedical engineering by reducing adverse immune responses and enhancing tissue integration. This paper explores the role of polymer chemistry in developing biopolymer-based surgical implants, highlighting key polymeric materials. These polymers are making them suitable for diverse biomedical applications. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1–6 Read article
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Polymer Chemistry-Guided Development of Biomimetic Composite Scaffolds
Abstract: Polymer chemistry plays a fundamental role in advancing biomaterials for anatomical tissue engineering, particularly in the design of composite scaffolds that replicate the intrinsic characteristics of native tissues. The regeneration of damaged tissues, especially within anatomically complex structures such as bone, cartilage, and skin, necessitates biomaterials that closely emulate the hierarchical architecture and biological functions of native extracellular matrices (ECMs). The capacity to replicate both mechanical and biochemical cues of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 7–13 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Adipofascial Flap Cover For Medial Maleolus Defect
Abstract: Soft tissue defects in the lower third of the leg, particularly over the medial malleolus, pose significant challenges due to poor vascularization and the limited availability of reliable local flaps. Over the past two decades, free tissue transfer has emerged as the preferred option for covering such defects. However, in certain cases, free flap transfer is not feasible due to patient-specific factors, cost constraints, or donor site morbidity. Traditional pedicled …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 6–10 Read article