Search
23 articles for “spray drying”
-
Carboxymethyl Cellulose-Based Spray-Dried Microspheres: Recent Advances and Applications in Targeted Drug Delivery Systems
Abstract: Microspheres are spherical particles ranging from 1 to 1000 μm, made from natural or synthetic polymers and inorganic materials. Their structure allows precise drug delivery, improving targeted release and minimizing off-target effects. Natural polymers such as starch, chitosan, and alginate are favored for their biodegradability, adhesion, and compatibility, enhancing mucosal interaction and residence time. Microspheres are widely used in site-specific drug delivery, gene therapy, and vaccine administration, improving immunogenicity, extending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 251–268 Read article
-
Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
-
A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
-
Solid Lipid Nanoparticles in Medicine: Formulation, Characterization and Future prospects
Abstract: An alternative to conventional colloidal carriers such liposomes, polymeric nanoparticles, and emulsions, solid lipid nanoparticles (SLNs) were created in the early 1990s. Benefits include targeted medicine distribution, controlled drug release, and improved stability. An extensive review of the excipients utilized, the production techniques, including the membrane contractor approach, and the possible advantages and disadvantages of SLNs is given in this work. It investigates secondary stabilization techniques like freeze-drying and spray-drying, …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 1–15 Read article
-
Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
-
Innovative Approaches in Excipient Co-Processing: A Comprehensive Review
Abstract: Co-processing of existing excipients is an innovative strategy in pharmaceutical formulation that offers a cost-effective, efficient alternative to the development of entirely new excipients. This process involves combining two or more well-established excipients to create new material with enhanced properties, thereby improving the functionality, performance, and manufacturability of pharmaceutical products. By leveraging the unique characteristics of each excipient, co-processing can significantly enhance attributes, such as flowability, compressibility, solubility, stability, and …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 34–51 Read article
-
Swift Solutions: The Science and Innovation Behind Fast-Dissolving Tablets
Abstract: Swift solutions in the context of fast dissolving tablets (FDTs) represent an innovative breakthrough in pharmaceutical science, aiming to provide rapid and effective drug delivery for patients who face difficulty swallowing conventional dosage forms. The science and innovation behind FDTs are rooted in advanced formulation techniques, material science, and drug delivery mechanisms that prioritize speed, convenience, and patient compliance. These tablets are formulated to dissolve quickly in the mouth, removing …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 26–36 Read article
-
Rapid-On-Tongue Delivery: A Review of ODT Technologies, Taste Masking and Compliance
Abstract: Orodispersible Tablets (ODTs), another name for Fast Dissolving Drug Delivery Systems (FDDS), are innovative drugs that dissolve in the mouth rapidly without requiring water. These will be especially helpful for kids, the elderly, and others who have difficulty swallowing ordinary tablets or capsules. Superdisintegrants are used in these pills to break down quickly in the mouth, while flavorings or sweeteners are used to cover up any harsh or unpleasant taste. …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 01–08 Read article
-
Polymer Composite-Assisted Crystal Engineering for Drug Synthesis and Property Control through Solid Solutions and Co-Crystals
Abstract: The long-standing problem of low aqueous solubility, which affects about 90% of all new drug molecules under development, requires an immediate need for alternative approaches apart from the usual practice of crystallization. Polymer-composite-assisted crystal engineering is a novel technique for overcoming the aforementioned problem. This involves the addition of accepted pharmaceutical polymers, such as HPMC, PVP, PEG, and Eudragit copolymers in a single process, which can promote nucleation, stabilize the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 172–189 Read article
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Modernizing Agriculture: The Evolution of a Multipurpose Farm Machine
Abstract: In India, a nation reliant on agriculture, 70% of the population makes their living from farming. However, we can see that as the population grows, the farm is divided up among the individuals; as a result, Indian farmers often own just two acres of land. Farmers also practice traditional farming since they are extremely poor and cannot afford to buy tractors or other expensive equipment. In general, bullocks, horses, and …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 2, Issue 1, 2024 · pp. 1–6 Read article
-
Optimization of Pesticide Requirement Calculations for IoT-Operated Hexacopter Delivery Systems
Abstract: The integration of Internet of Things (IoT) technology into precision agriculture has transformed pesticide application strategies, enabling resource-efficient and environmentally sustainable practices. This study presents a computational methodology for optimizing pesticide requirements in an IoT-operated hexacopter system, designed for dynamic, data-driven pesticide delivery. Leveraging a fusion of real-time telemetric data from onboard LiDAR, multispectral imaging sensors, and environmental monitoring modules, the system employs predictive analytics and edge computing to calculate …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 08–14 Read article
-
The Future of Farming with IoT-Operated Drones
Abstract: The integration of Internet of Things (IoT) technology with drone systems has revolutionized precision agriculture, offering innovative solutions to address the inefficiencies and environmental concerns linked to conventional pesticide application. This study explores the design, implementation, and impact of IoT-operated drones tailored for automated pesticide spraying. By leveraging real-time sensor data, AI-driven analytics, and cloud-based connectivity, these drones enable dynamic, data-informed decisions to optimize chemical application. Results indicate that IoT-enabled …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 20–26 Read article
-
ADAS Implementation & Drowsiness Detection in Vehicle
Abstract: Driver fatigue is a leading cause of road accidents, especially in public and commercial transportation, posing serious risks to passenger and pedestrian safety. To address this critical safety issue effectively, this research study presents an AI-powered ADAS designed specifically for BS6-compliant buses, using real-time fatigue detection to prevent accidents. The system integrates a Raspberry Pi equipped with an AI Hat+ module to monitor driver drowsiness by detecting prolonged eye closures …
Published in Journal of Mechatronics and Automation · Vol. 13, Issue 1, 2026 · pp. 28–36 Read article
-
Study of the response of Fenugreek Seedlings (Trigonella foenum-graecum L.) to some Plant Growth Regulators and Their effect on the production of the active Compound (Trigonelline)
Abstract: The experiment was conducted during the 2022–2023 academic year in the laboratories of the Department of Biology, Faculty of Education for Girls, University of Kufa, to investigate the effects of varying concentrations of gibberellic acid (GA₃) — specifically 0, 2, and 3 ppm — and salicylic acid (SA) (0, 2.5, 5 ppm) as well as the interaction between them on the germination percentage and some growth traits of fenugreek seedlings …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
Smart Firefighting Robot using Arduino Uno
Abstract: A fire is dangerous and can have many repercussions. Numerous accidents can be avoided by promptly identifying and putting out a fire. Human resources have been our mainstay thus far. The person's life is often in jeopardy as a result. Consequently, fire safety becomes essential to save lives. The fire extinguishing robot proposed and designed in this work locates the fire and utilizes sprinklers to extinguish it when the pump …
Published in International Journal of Electronics Automation · Vol. 3, Issue 1, 2025 · pp. 21–27 Read article
-
Allergic Reaction in Upper Respiratory Tract Infection (Anurjata Janya Swasa Roga) – An Ayurvedic Review and Treatment – A Case Study
Abstract: Respiratory tract infection affects the upper to lower part of the respiratory system including the nose to the alveoli of the lungs. There are two types of infections - upper respiratory infections - affecting the sinuses and throat. Upper respiratory tract infections include: common cold, epiglottitis, laryngitis, pharyngitis, and sinusitis. Lower respiratory tract infection - affects the respiratory tract and lungs. In general, lower respiratory tract infections last longer and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 26–32 Read article
-
Hydrolysis-Driven Optimization of Hydroxypropyl Maize Starch for Improved Micro-Pellet Binding and Quick Solubility of Spirulina-Based Micro-Pellets
Abstract: Acid hydrolysis is a well-established approach for modifying the physicochemical properties of polysaccharides & macromolecules including hydroxypropyl Maize starch (HPMS). In this study, the effect of varying concentrations of hydrochloric acid on the partial hydrolytic degradation of HPMS (Lycoat RS-780) was investigated at 85°C for 4 h, yielding polymers of different molecular weights. The Acid-mediated degradation effects on polymer characteristics were systematically assessed using capillary viscometry and gel permeation chromatography …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 3, 2026 Read article
-
Gypsum Addition in Moulding Sand to Manufacture Defect Free Tin Castings
Abstract: Sand molding is a versatile casting process that provides freedom of design with respect to size, shape, and product quality. Plaster casting is similar to sand molding process except that a plaster is substituted instead of sand. Plaster compound is composed of gypsum, which strengthens the mould. Parts made by this process are gears, valves, fittings, tooling, and ornaments. The finished product of plaster casting has a very high surface …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 2, 2023 · pp. 7–15 Read article
-
Autonomous Fire Suppression Robot Based on Arduino
Abstract: Fire hazards continue to pose serious risks in homes, workplaces, and industrial facilities, making rapid detection and early suppression crucial for minimizing damage and protecting lives. This paper presents the design and development of an autonomous fire suppression robot built around an Arduino- based control system. The robot is engineered to independently detect, approach, and extinguish small fires with minimal human interaction. It incorporates multiple sensing components, including flame sensors …
Published in Journal of Advancements in Robotics · Vol. 13, Issue 1, 2026 · pp. 26–32 Read article