Search
28 articles for “antifungal drugs”
-
Review of the Antifungal Drug Luconazole for the Treatment of Skin Infections
Abstract: Many U.S. researchers are still working on a broad-spectrum imidazole antifungal called Luliconazole to treat dermatophytic skin and nail infections. The in vitro activity of luliconazole against filamentous fungi, including dermatophytes, is among the highest of any antifungal drug tested to date. The unique molecular characteristics of a 10% solution of Luliconazole make it possible for the drug to quickly reach fungicidal concentrations in the nail unit, allowing it to …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 13–19 Read article
-
Mucormycosis: Review on the basis of Diagnosis Treatment, Preventive Measures, and Recent Research Approach
Abstract: Mucormycosis is a fungal infection called an angio-invasive disease due to invasion of fungi of the order Mucorales and zygomatic species which causes tissue infarction and necrosis. The main aim and purpose of this review are related to the overview of Etiopathogenesis of Mucormycosis, mortality due to various types of Mucormycosis, recent advances in diagnostic and treatment methods, and their diagnostic preventive measures. It shows serious and worrying mortality and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 3, 2021 · pp. 51–62 Read article
-
Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
-
FUNGI IN THE GLOBAL BIOECONOMY: HARNESSING THE R POTENTIAL ACROSS AGRICULTURE, MEDICINE, INDUSTRY, AND ENVIRONMENTAL SUSTAINABILITY
Abstract: One of the most diverse and functionally versatile groups of living organisms, fungi has played a significant role in maintaining ecological balance, human well-being, agricultural production, and industrial processes. Despite their vast potential, the use of fungi systems in solving some of the most serious challenges facing the world today, such as climate change, food security, and AMR, is still in its infancy. New developments in genomics, biotechnology, and systems …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 20–27 Read article
-
Treating Tinea Capitis with Unani Formulation: A Case Study of 25-year-old Male Patient
Abstract: Tinea Capitis is a superficial fungal infection of scalp, mainly caused by dermatophytes Trichophyton tonsurans and Microsporum canis (highly inflammatory) and Microsporum audouinii are second most common cause. It has two types’ viz. endothrix and ectothrix. Tinea Capitis is also known as Ringworm of the scalp and Tinea tonsurans. In Unani System of Medicine Tinea is known as Qūbā, characterized by burning, itching along with roughness and desquamation over skin …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2020 · pp. 62–66 Read article
-
Formulation, Evaluation, and Stability Studies of a Topical Clotrimazole and Zinc Oxide Suspension with Enhanced Skin Protective Properties
Abstract: Background: Clotrimazole is a well-known antifungal agent frequently used in the treatment of various superficial fungal infections, while Zinc Oxide is a widely accepted skin protectant with soothing, astringent, and antimicrobial properties. Combining these agents in a topical suspension offers a dual therapeutic approach, enhancing both antifungal efficacy and skin protection. Objective: The objective of this study was to formulate, evaluate, and conduct stability studies on topical suspensions containing Clotrimazole …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 22–31 Read article
-
Veterinary Mycology: Fungal Infections in Livestock and Companion Animals
Abstract: Fungal infections represent a significant yet often underestimated challenge in veterinary medicine, affecting both livestock and companion animals. Veterinary mycology encompasses a diverse group of pathogens, including yeasts, molds, dimorphic fungi, and dermatophytes, that can cause localized or systemic diseases with substantial health, economic, and zoonotic implications. In livestock species, such as cattle, sheep, goats, poultry, pigs, horses, and camels, fungal infections manifest as dermatophytosis, mycotic mastitis, aspergillosis, keratomycosis, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 44–51 Read article
-
Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
-
Use of NMR and Other Spectroscopy Techniques in Heterocyclic Oxadiazole Derivatives Studies: A Review
Abstract: It was possible to create a number of novel symmetrical 2,5-dialkyl-1,3,4-oxadiazoles with substituents including carboxymethylamino, isopropyloxycarbonylmethylamino, and bromine at the terminal positions of the alkyl groups. The multistep process that was devised used hydrazine hydrate, phosphorus oxychloride, and commercially available acid chlorides that varied in alkyl chain length and terminal substituent.Diisopropyliminodiacetate was an easy way to substitute the intermediate bromine-containing 2,5-dialkyl-1,3,4-oxadiazoles. This was followed by hydrolysis in an aqueous methanol …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 07–13 Read article
-
Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy
Abstract: This review provides an in-depth exploration of the evolution of ointment formulations, particularly considering the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges, such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift toward more advanced, innovative formulations that aim to address …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 14–23 Read article
-
Comprehensive Strategies for the Prevention and Management of Genital Thrush in Males and Females: A Public Health Approach in Punjab (September 2024 to February 2025)
Abstract: Background: Genital thrush, a common fungal infection caused mainly by Candida albicans, affected both men and women, leading to itching, discomfort, and recurrent infections. In Punjab, high humidity, poor hygiene awareness, excessive antibiotic use, and limited access to healthcare contributed to its widespread occurrence. Without effective prevention and management strategies, the condition significantly impacted quality of life. Addressing this issue through a public health approach was essential for reducing its …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
-
A Review on Medicinal Properties of Chickpea and Its Profile
Abstract: Cicer arietinum is the most well-known vegetable and seen everywhere in the world, particularly in Afro-Asian nations. It has a place with family Fabaceae and appropriated in tropical, sub-tropical and calm districts. It is an annual crop with 20–100 cm tallness and the stems are spread, erect while root framework is vigorous and leaves are made of 11–15 individual handouts which are oval fit as a fiddle. The blossoms are …
Published in Research and Reviews : Journal of Crop science and Technology Read article
-
A Scientific Review on Phyto-pharmacological Properties of Moringa olifera Lam
Abstract: Moringa oleifera Lam. (Moringaceae) has been used since times to treat various health ailments. Different parts of plant have been used by traditional physicians. However, the dried entire fruit is more commonly used as Sehjana in Unani Medicine. Sehjana is a famous Indian drug used in a number of pathological conditions. Various parts of this plant act as cardiac and circulatory stimulants, possess anti-tumour, antipyretic, antiepileptic, anti-inflammatory, antiulcer, antispasmodic, diuretic, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2020 · pp. 1–11 Read article
-
Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
-
Zn Doped CuO Nanoparticles for Increasing the Longevity of The Agricultural Products †
Abstract: Nanotechnology is an enabling technology at the service of mankind. Indeed, enhancing the long-term storage of agricultural products (post-harvest during transportation and storage) in general and apples and tomatoes, in particular, is a challenge. Zn-doped CuO is a proven nanomaterial with special ability to kill plant pathogens as well as a variety of microorganisms (bacteria, virus, and fungus). Much of the review is focused on the landmark papers published by …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 14–29 Read article
-
Carica papaya Linn.: A review on Nutritional and Medicinal Value of Papaya
Abstract: Papaya (Carica papaya Linn.) is a popular fruit tree in the tropical part of the world. It is a delicious, sweet fruit with a pleasant aroma. The papaya is consumed worldwide as a fresh fruit and vegetable. which is healthy for humans because all parts of the plant, including fruit, stem, bark, peel, fruit, seeds, and pulp, have medicinal properties. Papaya also has nutritional value and is also used as …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 67–75 Read article
-
Synthesis, Antibacterial Evaluation and Antifungal Study of New Biochemical Derivatives
Abstract: Bacterial and fungal infections have become widespread recently due to the spread of epidemics, diseases, and bacterial infections. As a result, infection rates have increased, prompting many researchers to develop new antibiotics to reduce the spread of these prevalent diseases. Researchers have prepared biochemical compounds similar in structure to drugs that eliminate infections and reduce their spread. One such derivative is imidazole; a well-known compound used in many medications for …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
-
Development, Optimization and Evaluation of Polyherbal Gel Comprising of Azadirachta Indica, Calendula Officenalis, Turmeric and Aloe-vera for Treatment of Wound
Abstract: Azadirachta indica, Calendula officinalis, Turmeric (Curcuma longa), and Aloe-vera are known to possess numerous medicinal properties. These herbs have been traditionally used across various cultures for the treatment of a wide range of ailments due to their potent therapeutic effects. Individually, they have demonstrated efficacy in addressing conditions such as acne, diabetes, wound healing, gastric ulcers, first-degree burns, psoriasis, arthritis, and pneumonia. Additionally, they are known for their antimicrobial, anti-inflammatory, …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 41–53 Read article
-
Formation, Organic Investigation, Fluorescence Study of New Cyclic Derivatives of Thiophane-Triazole Compounds
Abstract: Azo compounds are used as intermediates in the preparation of many well-known and diverse organic derivatives. Cyclical or related azo derivatives, such as triazoles and thiophenes, possess useful applications in medicinal and pharmaceutical chemistry. Thiophene compounds and their derivatives have demonstrated a variety of biological activities, including antibacterial, antifungal, anti-tuberculosis, anti-inflammatory, analgesic, sedative, and hypnotic properties, immunosuppressive, and antihypertensive properties. Furthermore, thiophene derivatives can be used in the treatment of …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 1–13 Read article
-
Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article