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34 articles for “antidiabetic”
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Antidiabetic Potential of Bryophyllum pinnatum: A Study on its Pharmacological Effects and Synergistic Action with Glibenclamide
Abstract: Diabetes is a long-term metabolic disorder that profoundly impacts an individual’s overall health, social interactions, and quality of life. While significant progress has been made in diabetes management with the use of medications such as insulin and oral hypoglycemic agents, the limitations of these existing treatments highlight the need for new therapeutic alternatives. Moreover, the high cost of current diabetes medications makes them inaccessible to many, particularly in rural areas …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 18–30 Read article
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Development and Characterization of a Solid Dispersion of an Anti-Diabetic Drug Using Pectin as a Natural Polymer
Abstract: Aim: The current study sought to improve the solubility and oral bioavailability of gliclazide by creating solid dispersions and oral dispersible tablets (ODTs) with enhanced physicochemical characteristics and maintained antidiabetic action. Methods: Preformulation studies were conducted to evaluate the physicochemical properties of gliclazide, including physical appearance, melting point, solubility, and partition coefficient. Solid dispersions were prepared using hydrophilic carriers-pectin and PVP K30, and subsequently characterized by Fourier Transform Infrared Spectroscopy …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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A Systemic Review: Pithecellobium dulce (Jangal Jalebi)
Abstract: Pithecellobium dulce (Roxb.) Benth., commonly referred to as Jangal Jalebi, Vilayati Babul, or Manila Tamarind, is a versatile tree in the Leguminosae (Fabaceae) family. It is commonly found in tropical and subtropical areas and is valued for its ecological, medicinal, and nutritional benefits. The plant is rich in a variety of bioactive compounds, including flavonoids, alkaloids, phenols, glycosides, tannins, saponins, terpenoids, and steroids, which enhance its pharmacological potential. Different extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 14–20 Read article
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Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century
Abstract: Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 26–34 Read article
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Cucumis Sativus: A Review
Abstract: The family Cucurbitaceae includes the cucumber (Cucumis sativus L.). 30 species of Cucumis are distributed in Africa and Asia. One of the first vegetables to be farmed, cucumbers are native to the tropics. It has almost 3,000 years of historical documentation (Yawalkar, 1985). Widespread cultivation of Cucumis sativus (CS) is found in Bangladesh (including the Chittagong Hill Tracts, Gazipur, Sherpur, Cox's Bazar, Tangail, and other forests), the Indian subcontinent, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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The Potential of Guava Leaf-Enriched Chocolate in Sugar-Free Anti-Diabetic Confectionery: A Review
Abstract: People of all age groups enjoy chocolate however, it is often linked to health issues like obesity, hypertension, diabetes, and cardiovascular diseases. This study aimed to develop a medicinal chocolate suitable for diabetic individuals by incorporating herbal ingredients. Specifically, guava leaves (Psidium guajava), known for their rich vitamin and antioxidant content and their ability to help regulate blood sugar, were used. The chocolate formulation included guava leaf powder, coffee, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 55–63 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article
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Evaluation of Prescribing Pattern of Drugs in Hemodialysis Patients
Abstract: Background: Patients undergoing hemodialysis often exhibit a high level of dependency and frequently present with multiple co-morbid conditions Chronic kidney disease (CKD) poses a significant global public health challenge, with its association with numerous complications. Prescribing medications appropriately for individuals with CKD presents a substantial challenge. Objective: The study aimed to assess the prescribing patterns of drugs in hemodialysis patients. Results: Out of the total 82 selected patients, 42 (51%) …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Novel Nanotherapeutics for the Management of Diabetes
Abstract: Diabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and in case of Type …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 46–67 Read article
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Biochemical Estimation of Allaxon Induced Hyperglycemia in Rats Treated with Polyherbal Preparation of Two of Indian Medicinal Plants Cordia Myxa and Canscora Diffusa
Abstract: A systematic study was conducted on extracts of Cordia myxa and Canscora diffusa to evaluate their qualitative chemical composition, phytochemical content, and antidiabetic activity. Then the Poly herbal extract is prepared with the selected plant powders, subjected to acute-toxicity studies for dose fixation. The herbal extracts formulation was prepared taking three selected dosages. The preparations are evaluated for anti-diabetic activity using Steptozotocine and Alloxan induced diabetic models in rats. The …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 52–60 Read article
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Integrating Horticultural Techniques for the Propagation of Ethnomedicinal Pteridophytes in the Himalayan Region
Abstract: The Doon Valley, including the regions of Dehradun, Mussoorie, and Chakrata in Uttarakhand, India, is rich in ecological and medicinal plant diversity. This study focuses on the geographical distribution, habitats, and medicinal applications of 28 pteridophyte species found in these regions. Detailed field observations and data collection from various scientific journals, databases, and publications have contributed to understanding the traditional and pharmacological uses of these plants. The results show that …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 1–19 Read article
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In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus.
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology Read article
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A Review on Medicinal Properties of Chickpea and Its Profile
Abstract: Cicer arietinum is the most well-known vegetable and seen everywhere in the world, particularly in Afro-Asian nations. It has a place with family Fabaceae and appropriated in tropical, sub-tropical and calm districts. It is an annual crop with 20–100 cm tallness and the stems are spread, erect while root framework is vigorous and leaves are made of 11–15 individual handouts which are oval fit as a fiddle. The blossoms are …
Published in Research and Reviews : Journal of Crop science and Technology Read article
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A Review On Wonder Plant Aloe Vera
Abstract: For millennia, people have utilized and appreciated the health, aesthetic, therapeutic, and skin- care benefits of aloe vera plants. Aloe is a plant that grows in dry regions of Africa, Asia, Europe, and America. It has approximately 300 species. Aloe barbadensis miller is the botanical name of aloe vera. It is a perennial, xerophytic, succulent, shrubby or arborescent plant with pea-green hue that is a member of the Asphodelaceae (Liliaceae) …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 1–9 Read article
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Assessing the Efficacy of Carica Papaya Leaf Extract in Preventing Thrombocytopenia: A Review
Abstract: A clinical condition known as thrombocytopenia is characterized by a low platelet count (less than 150 × 103/μL) in the blood, which leads to an imbalance in hemostasis and can result in multiple deadly consequences. Although the exact causes are not always known, they always lead to death by interfering with the formation of platelets and encouraging their destruction. Research demonstrates that Carica papaya leaf has special medicinal and therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 25–33 Read article
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A Review on Phytochemistry and Pharmacological Properties of Curcuma amada (Zingiberaceae)
Abstract: Plant has been employed in traditional medicine since ancient times. Curcuma amada Roxb. (Mango ginger), is a member of Zingiberaceae family and the Curcuma genus. It is a distinctive spice that shares a similar appearance with ginger but provides a raw mango taste. It is considered as a valuable plant in traditional medicine which plays a crucial function in both the food and pharmaceutical industries. Ayurveda and Unani medicinal traditions …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 10–20 Read article
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Biosynthesis of Zinc Oxide Nanoparticles and Their Revolutionary Impacts on Agroindustry: Review
Abstract: Nanotechnology is a new approach of science which provides alternative tool in many fields including agriculture. This comprehensive review focuses on the biosynthesis and characterization of zinc oxide nanoparticles (ZnO NPs), highlighting their vast potential in agroindustry applications. Unlike traditional physical and chemical methods, which are often costly, time-consuming, and involve hazardous materials, this review explores the promising biological synthesis routes, offering a more sustainable and eco-friendly alternative for producing …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 33–50 Read article
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A Comprehensive Review on Pharmacological Properties of Coumarins
Abstract: Coumarins are a diverse group of secondary metabolites found in a variety of plant species (over 1200 different coumarins have been identified from natural sources, especially plants), as well as in fungi and microorganisms. Coumarin is a simple, widely occurring chemical structure in nature, present in many plants, fungi, and bacteria. In recent years, these natural compounds have attracted growing interest from the scientific community due to their broad spectrum …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 12–17 Read article