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136 articles for “Metabolic Response”
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A Study of Metabolic Responses of R.Q, VO₂, and VCO₂ in Two Different Swimming Strokes
Abstract: This study investigates the metabolic responses, including Respiratory Quotient (R.Q), oxygen intake (VO₂), and carbon dioxide output (VCO₂), in freestyle and butterfly stroke swimmers. Understanding these responses is crucial for optimizing training and improving competitive performance. The study employed a comparative cross-sectional design involving 30 university-level swimmers (15 freestyle and 15 butterfly) who completed treadmill tests. Measurements of VO₂ and VCO₂ were taken using an S147 Rapid Response O₂/CO₂ Analyzer, …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Dietary Acid Load and Metabolic Responses in Chronic Kidney Disease: A Prospective Interventional Study
Abstract: Chronic kidney disease (CKD) is associated with metabolic disturbances, including metabolic acidosis, which may contribute to disease progression and nutritional deterioration. Dietary acid load is influenced by the composition of the diet and may affect systemic acid–base balance in patients with impaired renal function. The present study evaluated the effect of a low dietary acid load on biochemical and nutritional outcomes among patients with CKD. A prospective interventional study was …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Pharmacogenomics and Precision Medicine an Evolving Analytical Clinical Tools for Future Medicine – A Narrative Review
Abstract: The term Pharmacogenomics is coined as an emerging field that exactly examines how the genetic variations influence the individual responses towards medications. This discipline in turn integrates the pharmacology as well as genomics to facilitate the personalized medicine, encouraging the healthcare providers to tailor their drug therapies based on individual patient’s genetic profile. Key applications include optimizing drug efficacy, minimizing adverse effects, and enhancing treatment outcomes across various medical fields, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 44–52 Read article
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Emerging Therapeutic Discovery Against Escherichia coli Infection by Rational Inhibition of Fatty Acid Responsive Transcription Factor: Theoretical Molecular Investigations of Some Metabolites as Inhibitors of Fatty Acid Metabolism Protein
Abstract: For the discovery of effective agent for overcoming resistance against Escherichia coli (E. coli) bacteria by modulating Fatty Acid Metabolism Protein (FadR)—a Fatty Acid Responsive Transcription Factor. The present study involved discovery of some metabolites of furan, furan-2-yl, macrolactin, and chromene scaffold via in silico structure-based drug design (SBDD) technique by utilizing the Maestro 9.1 software. The study will provide clues, motivate, and throw light on imperative aspects for the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 1–7 Read article
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Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Growth and Nitrogen (N) Metabolizing Enzymes of Mesophilic and Psychrophilic Heterocystous Cyanobacteria—In Response to Temperature Regimes
Abstract: The increased NR & NiR activity, GS and nitrogenase activities at 25°C and 35°C in psychrophilic and mesophilic organisms indicates that the Arctic isolate is a psychrotolerant as it shows increased enzyme levels than its original temperature in which we isolated the organism though biomass was greater at 3°C. The biomass and enzyme data indicates cyanobacteria are the initiators of primary colonization in polar and alpine environments and are responsible …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 31–43 Read article
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Pharmacogenomics in Anesthesia: Individualized Drug Responses
Abstract: Pharmacogenomics is the study of how a person’s genes influence how they react to medications. Pharmacology, the study of medications, and genomics, the examination of genes and their functions, merge in this field to develop safe, effective drugs that can be prescribed based on an individual’s genetic makeup. Pharmacogenomics examines how an individual’s unique genetic makeup can influence their responses to certain drugs. In anesthesia, where individual responses to pain …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 83–95 Read article
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Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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The Unseen World Within: Decoding the Intricacies of Gut Microbiota and Its Impact on Human Health
Abstract: This comprehensive review delves into the multifaceted role of the gut microbiota in human health, elucidating its impact on diverse physiological processes, immune responses, and metabolic diseases. The intricate interplay of diet, genetics, and environmental factors is explored in shaping the composition and function of the gut microbiota, with consequential effects on conditions ranging from metabolic disorders to inflammatory bowel diseases and mental health. Therapeutic interventions, including probiotics, prebiotics, and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 3, 2023 · pp. 12–21 Read article
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Nutritional Modulation of Gene Expression: Insights from SNPs, CNVs, and Microsatellite Markers in Animal Systems
Abstract: Nutritional modulation of gene expression represents a critical interface between diet and the genome, shaping metabolic efficiency, health, and productivity in animal systems. Genetic variations such as single nucleotide polymorphisms (SNPs), copy number variants (CNVs), and microsatellite markers contribute to differential gene regulation in response to dietary inputs. This review synthesizes current knowledge on how these molecular markers influence nutrient driven gene expression and phenotypic outcomes in livestock species. SNPs …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Antibacterial Activity of Plant Extracts and Its Phytochemical Analysis
Abstract: Emergence of multi-drug resistance in human and animal pathogenic bacteria as well as undesirable side effects of certain antibiotics has triggered immense interest in the search for antimicrobial drug of plant origin since there is no resistance developed to the drugs that are of plant origin. The antibiotic resistance was observed by testing with commonly used antibiotics against test microorganisms and then diameter of zone of inhibition was compared to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 1–11 Read article
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Some Physiological Aspects of the Fresh Water Fish Channa Orientalis (Sch.)
Abstract: The fishes and their diseases have importance in life of human due to its high nutritive value. Phosphate and Chloride is an important chemical constituent of fishes which plays important role in the development and metabolism of fish. The present investigation was carried out to study the chloride content and phosphate content of Channa orientalis. It was observed that, phosphate was responsible for metabolism and chloride is an important ionic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 2, 2024 · pp. 22–26 Read article
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Gut Feelings: Unravelling the Secrets of the Microbial Universe Within
Abstract: The human digestive system hosts a varied and dynamic community of microorganisms, commonly known as the gut microbiota. This complex community, which includes various organisms such as bacteria, archaea, viruses, and fungi, is essential and important for numerous bodily functions such as metabolism, immune response, and cognitive development. The composition and vast diversity of the gut microbiome are shaped by diet, lifestyle, and genetic factors. Disruptions in this balance, known …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 21–33 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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Review of Ayurvedic Drugs on Acid-peptic Diseases Regarding Its Personalized Management
Abstract: Acid-peptic Disease (~Amlapitta) is an illness wide-spread all around the world. In Ayurveda, Vidahi (which cause burning) and Pitta (dosha responsible for metabolic activities) aggravating diet and stressful –sedentary life-style has been stated as one of the leading cause for acceleration of Amlapitta. Detailed reviewing of drugs given in Ayurvedic texts are done according to specific stage of disease, Amlapitta Dosha predominance, chronicity, associated conditions, dosage, Anupana etc. Screening the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 24–38 Read article
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Hydroponics Culture Regulated Metabolic Variations in Plants of Medicinal Value
Abstract: The current review chiefly brings to light the importance of alternative cultivation strategies for medicinal plants about the effective enhancement of the bioactive substances. The fast-paced society is favoring the need for its cost-effective cultivation and studying the effects thereafter. The mis-steps while collecting the plant from the wild lead to identification issues, genetic and phenotypic variations, variable bioactive substances/secondary metabolites, and toxic compounds. So, cultivation happening in controlled environments, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 14–20 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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How do Fungal Metabolites Influence Epithelial Integrity, Gut Barrier Function, and Nutrient Transport in Livestock? A Protection-Permeability Paradox
Abstract: The intestinal epithelium represents a dynamic interface between dietary substrates, resident microorganisms, and host tissues, linking barrier integrity with nutrient acquisition and metabolic homeostasis. Fungal metabolites are increasingly recognized as biologically active signals rather than passive components of fermented feeds, yet their effects on the epithelial-nutrient interface remain fragmented across animal nutrition, microbiology, and gut physiology. This review examines how fungal-derived β-glucans, mannans, organic acids, peptides, phenolic derivatives, and other …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article