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224 articles for “Disease Modeling”
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The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Disease Prediction Using Ensemble Learning Models: A Comprehensive Approach
Abstract: In recent years, ensemble learning techniques have become pivotal in advancing predictive analytics within healthcare, particularly for early disease detection. The inherent variability and complexity of medical data, often characterized by high dimensionality, class imbalance, and noise, make it challenging for standalone classifiers to maintain high predictive accuracy. Ensemble learning, by integrating multiple models through bagging, boosting, or stacking, offers a more robust and generalizable approach. This study explores the …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 3, 2025 · pp. 26–33 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Analysis and Application of Mathematical Modeling in Malaria Disease Control
Abstract: In this paper, we develop a mathematical model to analyze malaria transmission dynamics, as malaria is an infectious disease caused by the spread of progenitor parasites to humans through the bite of the female Anopheles mosquito. Mathematical models have long served as a framework for understanding and managing the impact of malaria, which has affected populations for over a century. Our model incorporates infected individuals who may recover and later …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 2, 2025 · pp. 19–25 Read article
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Multiple Disease Prediction Using Machine Learning Algorithms
Abstract: The incorporation of machine learning algorithms into healthcare has transformed disease prediction and diagnosis. This research introduces a method for predicting various diseases using machine learning techniques. A comprehensive dataset, consisting of patient records, medical histories, and key disease-related features, was utilized to build predictive models. Data preprocessing methods, including feature selection and normalization, were implemented to clean and prepare the dataset. Several machine learning algorithms, such as Decision Trees, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 34–38 Read article
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Advancing Healthcare Systems: A Machine Learning Approach to Multi-Disease Prediction
Abstract: The integration of machine learning algorithms in healthcare has revolutionized the way we approach disease prediction and diagnosis. An attempt to employ machine learning techniques to forecast numerous diseases is presented in this study. A diverse dataset containing patient records, medical history, and relevant features for various diseases was used to develop predictive models. Feature selection and normalization were among the preprocessing methods used to clean and prepare the data. …
Published in Journal of Electronic Design Technology · Vol. 16, Issue 1, 2025 · pp. 1–6 Read article
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Using of Rat Model Over Other Species: A Review
Abstract: The first domesticated morphological features to be used in studies were rats. Scientists employed the brown rat Rattus norvegicus to study human biology and therapeutics two decades ago, focusing on the consequences of hunger and oxygen deprivation. Rats have been used to answer a wide range of basic science problems relevant to common human ailments in the fields of pharmacology, immunology, physiology, nutrition, behaviour, learning, and toxicity. The article gives …
Published in International Journal of Animal Biotechnology and Applications Read article
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Modeling the Novel Coronavirus Disease (COVID-19) as Hidden Markov Chains
Abstract: The Hidden Markov Model has over the years been an appropriate method for modeling diseases such as HIV AIDS, heart failure, and so on. With the ongoing pandemic affecting Nigeria by being responsible for 2,745 death cases out of 207,616 confirmed cases as of October 10, 2021, the need to study an important parameter of COVID-19, the case fatality rate by building a model and estimating the case fatality rate …
Published in Research & Reviews : Journal of Statistics Read article
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Advances in Biological Systems Modeling for Predicting Drug Effects in Chronic Disease
Abstract: Biological systems modeling has emerged as a promising tool for understanding and predicting the effects of drugs in the treatment of chronic diseases. Chronic diseases, such as diabetes, cardiovascular diseases, and neurodegenerative disorders pose significant challenges to traditional drug development due to their complex, multifactorial nature. Systems biology approaches, which integrate computational modeling with experimental data, provide a holistic view of disease mechanisms and treatment responses. This review explores recent …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 17–22 Read article
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An Empirical Study of Hyperparameter Impact on Deep Learning Models for Cardamom Leaf Disease Classification
Abstract: Recent advancements in deep learning models like convolutional neural networks and self- attention mechanisms have achieved great success in the field of plant disease classification. This study investigates the efficacy of two pre-trained models, ConvNeXT-Tiny and Swin Transformer-Tiny, for leaf disease classification in cardamom using a publicly available dataset constituting three categories of leaves, namely Healthy, Colletotrichum Blight and Phyllosticta Leaf Spot. The effectiveness of the models highly depends on …
Published in Current Trends in Information Technology · Vol. 15, Issue 3, 2025 · pp. 48–60 Read article
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Mathematical Modeling of Epidemics Using Stochastic Differential Equations: A Review
Abstract: The accurate modeling of infectious disease dynamics is crucial for predicting outbreaks and informing public health interventions. While deterministic models such as the SIR (Susceptible-Infected-Recovered) framework have traditionally been used to understand disease transmission, they often fail to account for the randomness inherent in real-world scenarios. Disease spread is influenced by numerous uncertain factors, including individual behavioral changes, environmental fluctuations, and imperfect data reporting. These uncertainties can significantly impact model …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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An Efficient CNN Model for Automated Cotton Leaf
Abstract: Timely and accurate identification of cotton leaf diseases are essential for maintaining healthy crop production and minimizing agricultural losses. Early detection allows farmers to take preventive or corrective measures, reducing the risk of disease spread and improving overall yield. In this study, we propose a Convolutional Neural Network (CNN) based model for the automated classification of cotton leaf diseases using image-based detection techniques. The model is trained on a diverse …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 3, 2025 · pp. 01–10 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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A study on IoT and AI for Predictive Modeling and Control of Infectious Disease Transmission
Abstract: Background: The global response to novel and recurring infectious diseases is frequently hindered by surveillance systems that are slow, siloed, and reactive. Traditional epidemiology relies on retrospective analysis of clinical reports, often missing the critical early phase of autocatalytic spread. The urgency of modern public health necessitates a shift toward real-time, predictive intelligence. Methods: This study investigates the development and deployment of a synergistic paradigm integrating the Internet of Things …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Data to Diagnosis: A Systematic Review of AI/ML in Healthcare
Abstract: Artificial Intelligence (AI) and Machine Learning (ML) are fast revolutionizing the diagnosis of healthcare by augmenting accuracy, speed, and efficiency. AI/ML technologies facilitate earlier and more accurate disease identification with advanced algorithms for image processing, predictive modelling, and pattern recognition, frequently outperforming conventional diagnostic techniques. This review delves into the key contribution of AI/ML in contemporary healthcare, such as its use in clinical data analysis, imaging reports, and patient histories …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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A Hybrid Machine Learning Approach for Cardiovascular Disease Prediction
Abstract: Heart disease ranks among the top causes of death globally. Accurately predicting cardiovascular conditions has become a key challenge in the realm of clinical data analysis. It has been shown that machine learning is an effective means of assisting with predicting and decision-making based on the large volume of data produced by the medical industry. In this study, we describe a unique approach that increases the prediction accuracy of heart-related …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 69–75 Read article
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Deep Learning models for real time detection of crop diseases in the Maharashtra/Mumbai district
Abstract: This research project addresses the critical agricultural challenge of crop disease management in the Maharashtra region of India by leveraging modern deep learning techniques. The primary objective is to identify, implement, and compare the efficacy of various deep learning architectures—including Convolutional Neural Networks (CNNs), MobileNet, and EfficientNet—for the real-time classification of diseases in key crops such as cotton, soybean, and sugarcane. A custom dataset of agricultural images specific to Maharashtra's …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 2, 2026 · pp. 36–48 Read article
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Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model
Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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Role of Artificial Intelligence in Simulation and Therapeutics in Neurodegenerative Diseases
Abstract: Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc., are a cause of significant mortality rates due to a lack of curative treatments and their complex nature. Traditional therapeutic methodologies have several disadvantages such as slow diagnosis and a lack of effective treatments. They mainly focused on the management of the disease rather than curing it. The integration of artificial intelligence in the simulation and therapeutics of neurodegenerative …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 19–29 Read article