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282 articles for “Clinical Outcome”
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Advances in Total Knee Replacement: A Systematic Review of Clinical Outcomes and Complications
Abstract: Total Knee Replacement (TKR) is a widely used surgical intervention for patients with knee osteoarthritis and other degenerative knee disorders, offering significant improvements in pain relief, functional restoration, and quality of life. This systematic review synthesizes data from multiple clinical studies to evaluate the outcomes and complications associated with TKR. To find applicable research published in the last ten years, a thorough search of electronic databases was performed. Randomised controlled …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 41–56 Read article
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Knowledge and awareness of final years dental and medical students towards management. and clinical outcomes of maxillary sinus squamous cell carcinoma 2021
Abstract: Background: - study aimed to assess dental and medical students' knowledge on managing and clinical outcomes of maxillary sinus squamous cell carcinoma, a preventable and treatable cancer, and to address delays in referral and treatment.. objective: -To assess a knowledge and awareness of management and clinical outcomes of maxillary sinus squamous cell carcinoma among final years dental students and medical students at university of Khartoum Materials and Methods: A cross-sectional …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 10–17 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Effectiveness of Evidence-Based Pediatric Nursing Practices on Clinical and Developmental Outcomes in Children: A Comprehensive Systematic Review
Abstract: Evidence-based pediatric nursing practices are essential for improving health outcomes among children by integrating clinical expertise with the best available research evidence and patient-centered care approaches. This systematic review examines the effectiveness of evidence-based pediatric nursing interventions on clinical and developmental outcomes in children across various healthcare settings. A comprehensive search of databases including PubMed, CINAHL, Scopus, and the Cochrane Library was conducted for studies published between 2016 and 2026. …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 Read article
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A brief survey on Alternative and Complementary Medicine with special reference to safety, toxins and toxicological concerns
Abstract: Alternative and Complementary Medicine (ACM) is a wide range of healthcare practices that may be used within or alongside conventional medicine, and many of these practices are rapidly becoming accepted and integrated into the modern healthcare system. In addition to traditional medicine systems (e.g. Ayurveda, Unani Medicine, Traditional Chinese Medicine, and Homeopathy), ACM includes practices that utilize natural remedies including herbal medicine, phytotherapy, naturopathy, acupuncture, yoga, and meditation. While these …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 30–45 Read article
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Leveraging Genome-Wide Association Studies for Precision Medicine in Cardiovascular Diseases
Abstract: Cardiovascular diseases (CVDs) are the leading cause of death globally, with complex etiologies involving genetic, environmental, and lifestyle factors. Genome-wide association studies (GWAS) have significantly advanced the understanding of genetic underpinnings of CVDs by identifying numerous risk loci and variants associated with various cardiovascular conditions. This review explores the potential of GWAS to drive precision medicine in cardiovascular diseases by linking genetic data with clinical outcomes, providing insights into disease …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 35–39 Read article
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Association of Metabolic Syndrome with Cholelithiasis in Female Patients and Its Impact on Clinical Management and Surgical Outcome
Abstract: Background: Metabolic syndrome (MetS) is associated with obesity, insulin resistance, dyslipidemia, and hypertension, which may predispose to gallstone formation. This study aimed to evaluate the association between MetS and cholelithiasis in female patients and to assess its impact on clinical presentation, surgical difficulty, and postoperative outcomes. Methods: A prospective observational study was conducted on 88 female patients with ultrasonography-confirmed cholelithiasis. Patients were divided into two groups: MetS (n=44) and non-MetS …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 · pp. 1–7 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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A Comprehensive Review on Male Infertility
Abstract: The failure to attain a clinical pregnancy naturally after one year of unprotected intercourse is termed as infertility. Some of the factors that contribute to Infertility are late marriages, advanced age, genetics and lifestyle to name a few. To tackle this scenario, infertile and sub fertile couples take the aid of assisted reproductive technology. Intra uterine insemination (IUI), In vitro fertilization (IVF), Intra cytoplasmic sperm injection (ICSI), surgical sperm retrieval …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 95–103 Read article
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Comparison of Several Clinical Scoring Systems in Predicting the Outcome of Variceal Bleeding
Abstract: Background: Stratification of variceal bleeding patients into high-risk and low-risk group is very important to guide them through the suitable clinical pathway and to save the medical costs. We purposed to find out the best scoring system in the prediction of rebleeding and death after variceal bleeding by comparing four clinical scoring systems(clinical Rockall score, complete Rockall score, AIMS65 score, Child-Pugh score) which seemed to be applicable and simple. Method: …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 2, 2025 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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A Study on Clinical Characteristics and The Impact Of Covid-19 In Hemodialysis Patients
Abstract: Background: The Corona Viruses Disease-19 pandemic has severely impacted Hemodialysis patients, who are vulnerable due to compromised immune systems and underlying comorbidities. Frequent Dialysis center visits increase their exposure risk to severe acute respiratory syndrome- Coronavirus Disease, and chronic inflammation, uremia, and immunosenescence may impair their immune response. Methods: This retrospective study included 60 Hemodialysis patients diagnosed with COVID-19 between January -July 2024. Data on demographics, clinical characteristics, laboratory results …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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Clinical and Administrative Processes in Contemporary Dental Practice
Abstract: Maintaining operational efficiency, providing patients with high-quality oral healthcare, and guaranteeing patient pleasure all depend on a dental clinic operating well. This article looks at the administrative procedures, clinical workflow, and organizational structure that go into running a dental clinic on a daily basis. Patient scheduling, infection control procedures, dental equipment management, staff roles and duties, record-keeping, and adherence to legal and ethical standards are some of the important topics …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 19–24 Read article
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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A Short Review on Long-Term Effects of Botox on Neuronal Sprouting: Mechanisms and Its Clinical Implications
Abstract: Botulinum toxin (Botox) is extensively used for its ability to induce temporary muscle paralysis through inhibition of acetylcholine release at neuromuscular junctions. While its short-term effects are well documented, emerging evidence suggests that chronic use of Botox may trigger neuronal sprouting, a process that could have significant long-term implications. This review synthesizes current research on the mechanisms by which Botox induces nerve sprouting and evaluates the clinical outcomes associated with …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 72–87 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Clinical study of ERAS programs for chronic anal diseases
Abstract: Background: ERAS protocols were implemented for the management of chronic anal diseases in our clinical setting.Patients and Methods: The clinical outcomes of these ERAS programs were systematically analyzed. Results: Our study revealed significant improvements with the implemented ERAS protocols. Specifically, the average time for healing with these protocols was 7.9±0.76 days, notably shorter compared to the previous standard protocols which averaged 14.3±0.4 days. Moreover, there was a marked reduction in …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 39–43 Read article
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A Study on High-Risk Pregnancy and Its Management: Role of Obstetric Nurses in Improving Maternal and Fetal Outcomes
Abstract: High-risk pregnancy is a major challenge in maternal and neonatal healthcare and is associated with increased morbidity and mortality among mothers and new-borns, particularly in developing regions where access to quality healthcare services remains uneven, this article examines the concept, classification, risk factors, pathophysiology, and management of high-risk pregnancy with a strong focus on the role of obstetric nurses in improving maternal and fetal outcomes, obstetric nurses play a central …
Published in International Journal of Midwifery Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 26–43 Read article
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Advances in Simulation and Surgical Skill Training Evolution: Narrative Integrative Review
Abstract: Simulation-based education has emerged as a cornerstone of contemporary general surgery training, driven by increasing emphasis on patient safety, competency-based education, and rapid technological innovation. Traditional apprenticeship models, while foundational, are constrained by reduced operative exposure, work-hour limitations, and variability in clinical case mix. In this context, simulation provides a structured, reproducible, and safe environment for acquisition, assessment, and refinement of surgical skills across the training continuum. This narrative review …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 7–13 Read article
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The Role of Gut Microbiota in the Health Effects of Fermented Dairy Products
Abstract: The human gut microbiota plays a crucial role in maintaining physiological health, influencing digestion, metabolism, immune function, and even mental well-being. Among dietary interventions aimed at modulating gut microbiota, fermented dairy products have emerged as particularly promising due to their rich content of live microorganisms, bioactive compounds, and nutrients. This review explores the intricate interactions between fermented dairy products and the gut microbiota, highlighting their potential health benefits and underlying …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 5–10 Read article