24 publications
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Published Subscription Review Article
Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable TherapeuticsBy Atul Khajuria, Ashish Kumar
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article →
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Published Subscription Review Article
Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.By Atul Khajuria, Ashish Kumar
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article →
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Published Subscription Review Article
Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood DisordersBy Atul Khajuria
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article →
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Published Subscription Review Article
Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid TumorsBy Atul Khajuria, Ashish Kumar
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article →
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Published Subscription Original Research
The Importance of Self-Care for Healthcare Professionals in North India: A Regional Analysis of Burnout, Resilience and Institutional SupportBy Atul Khajuria, J. Samuel Kamanda, Eric Kwasi Elliason, Christian Gendemeh
Abstract: Background: Burnout in healthcare professionals is described using the framework of Occupational Health and Resilience Theory, where self-care is an individual-level coping mechanism and institutional support is an organizational-level moderator. However, there is a lack of regional data from North India on the structural and contextual factors influencing burnout. Healthcare workers (HCWs) in North India face mounting pressures due to high patient loads, limited mental health resources, and overlapping professional …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 24–29 Read article →
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Published Subscription Review Article
Utilization and Socioeconomic Impact of Biofuel Adoption Among Farming Communities in Fatehgarh Sahib, PunjabBy Stephen Monday, Atul Khajuria, Shu-Achet Daniel Gimbason
Abstract: With the increasing consumption of energy and environmental issues, transformation toward renewable energy is being considered as a trend globally. Biofuels such as biogas and biodiesel provide potential alternative to fossil based fuel, particularly, in the rural parts of India, including Punjab. These clean sources, however, are not only contributing to environment but also have a potential to improve the rural economy by saving costs and having better health. Despite …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 1, 2026 · pp. 38–45 Read article →
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Published Subscription Review Article
Climate-Driven Shifts in Vector-Borne Disease Ecology Across South AsiaBy Atul Khajuria, Stephen Monday, Eric Kwasi Elliason, Gagan, J. Samuel Kamanda
Abstract: Climate change remains one of the most important phenomena affecting the geographical distribution and movement patterns of vector-borne diseases. In South Asia – characterized by high population density, rich biodiversity, and sharp climatic differences – there is growing evidence of the relationship between increasing temperatures and erratic precipitation, along with the behavior of insect vectors. This research aims to evaluate the effects of climate environmental changes on the distribution and …
Published in International Journal of Insects · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article →
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Published Subscription Original Research
Heavy Metal Exposure in Industrial Workers of PunjabBy Stephen Monday, Atul Khajuria, Eric Kwasi Elliason, Gagan, J. Samuel Kamanda
Abstract: Background: Particularly for those in sectors such textiles, metallurgy, and electronics, heavy metal exposure in industrial environments is a major health issue. A range of negative health effects can result from metal exposure including lead (Pb), cadmium (Cd), chromium (Cr), arsenic (As), and nickel (Ni), including neurological, pulmonary, and renal ones. There is little information available on the degree of heavy metal exposure industrial workers in Punjab, India experience. Objective: …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–7 Read article →
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Published Subscription Original Research
Exploring the Genetic and Environmental Factors Contributing to Ovarian Cancer in Women in Mumbai, IndiaBy Atul Khajuria, Eric Kwasi Elliason, Stephen Monday, J. Samuel Kamanda
Abstract: Background: Ovarian cancer incidence in Mumbai has risen by 30% over the past decade, with an age-standardized rate of 9.1 per 100,000 women, contrasting stable trends in Western nations. This study investigates the interplay of genetic and environmental factors driving this disparity in Mumbai’s diverse population. Methods: A hospital-based case-control study was conducted at a hospital, enrolling 200 epithelial ovarian cancer cases (aged 30–70 years) and 400 age-matched controls. Germline …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 12–17 Read article →
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Published Subscription Original Research
Alternative Medicine in Punjab: Gendered Patterns in Efficacy and Safety OutcomesBy J. Samuel Kamanda, Atul Khajuria, Eric Kwasi Elliason, Stephen Monday
Abstract: Background: Alternative medicine remains an integral part of healthcare practices in Punjab, India. However, disparities based on gender and regional differences influence its usage, efficacy, and safety outcomes. Objective: To assess gendered and regional patterns in the use, perceived benefits, and safety concerns of alternative medicine among adults in Punjab. Methods: A mixed-methods, cross-sectional study was conducted among 620 adults (300 men, 320 women) from both urban and rural regions …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 9–12 Read article →
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Published Subscription Original Research
Perception and Implementation of Sports Safety Measures Among University Physical Education Instructors in Punjab: A Cross-Sectional StudyBy Atul Khajuria, Christian Gendemeh, Stephen Monday, Samuel Kamanda
Abstract: Introduction: Considerable attention must be focused on sports safety as it is a constituent of thephysical education (PE) curriculum at the university level, in view of the frequent and vigorous engagement in physical activities. While there is general acknowledgement of the existence of safetymeasures, the extent to which such measures are put into practice may differ. This research examines the perceptions and practices related to sports safety of university PE …
Published in Recent Trends in Sports · Vol. 2, Issue 2, 2025 · pp. 45–55 Read article →
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Published Subscription Original Research
The Role of Indigenous Knowledge Systems in Cultural Heritage Preservation under NEP 2020By Atul Khajuria, Stephen Monday, Christian Gendemeh, J. Samuel Kamanda, Eric Kwasi Ellison
Abstract: In Introduction, This study explores the roles of India’s National Education Policy (NEP) 2020 in cultural heritage preservation through indigenous knowledge systems. These include traditional arts, crafts, ecological practices, and languages. It also includes perspectives through gender and regional lenses on this integration. In Methodology, Confirming the study, a survey was held with 2,300 participants, with an equal split of male, female and non-binary, from rural and urban settings. The …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article →
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Published Subscription Original Research
Assessing the Effectiveness of Vocational Education and Training (TVET) in Preparing Students for the Workforce in LiberiaBy Atul Khajuria, Stephen Monday, Christian Gendemeh, J. Samuel Kamanda4
Abstract: Training in Vocational and Educational Training (TVET) is important for students as it enables them to gain practical skills for employment. In Liberia, the main concern of TVET programs is the increasing supply needs for skilled workers in different industries Liberian industries. This research seeks to explore the effectiveness of these programs in Liberia in relation to employment and self-employment opportunities from the 833 respondents distributed across various TVET institutions. …
Published in Recent Trends in Social Studies · Vol. 2, Issue 2, 2025 · pp. 31–38 Read article →
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Published Subscription Original Research
Assessing the Increasing Incidence of Prostate Cancer in Urban Delhi: Risk Factors, Early Detection, and Treatment ChallengesBy Eric Kwasi Elliason, Atul Khajuria, Stephen Monday, J. Samuel Kamanda
Abstract: Background: Prostate cancer has emerged as the second most prevalent cancer among men in India, with rapidly increasing incidence rates in urban areas like Delhi. This rise is attributed to urbanization, lifestyle changes (high-fat diets, tobacco use, sedentary behavior), increased life expectancy, and improved diagnostics. Despite its growing burden, low awareness, limited screening programs, and treatment barriers hinder early detection and effective management. This study examines the epidemiological trends, risk …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 21–28 Read article →
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Published Subscription Original Research
Breast Cancer Screening Awareness and Participation Among Women in North IndiaBy Eric Kwasi Elliason, Atul Khajuria, Stephen Monday, J. Samuel Kamanda
Abstract: Breast cancer is the most prevalent malignancy among Indian women, accounting for 25% of all female cancers (ICMR, 2020). Significant urban-rural disparities in screening persist across North India due to socioeconomic, cultural, and healthcare access barriers. This study evaluates these disparities to inform targeted interventions. A cross-sectional study was conducted among 1,500 women (750 urban, 750 rural) in Delhi, Uttar Pradesh, Punjab, and Haryana, using stratified random sampling. Data were …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 43–50 Read article →
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Published Subscription Original Research
The Role of Helicobacter pylori in Stomach Cancer Incidence: A Study in Rural Communities in RajasthanBy Atul Khajuria, Eric Kwasi Elliasion, Stephen Monday, J. Samuel Kamanda
Abstract: Background: Stomach cancer remains a major global health challenge, with a particularly high burden in developing regions. Helicobacter pylori (H. pylori) infection is a known risk factor for gastric malignancy. In India, especially in rural states like Rajasthan, there is limited data on the prevalence of H. pylori and its association with stomach cancer, despite the high incidence of gastric diseases. Methods: This cross-sectional study was conducted among rural communities …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 45–50 Read article →
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Published Subscription Original Research
Comprehensive Strategies for the Prevention and Management of Genital Thrush in Males and Females: A Public Health Approach in Punjab (September 2024 to February 2025)By Stephen Monday, Atul Khajuria, Eric Kwasi Elliasion, Gagan, J. Samuel Kamanda
Abstract: Background: Genital thrush, a common fungal infection caused mainly by Candida albicans, affected both men and women, leading to itching, discomfort, and recurrent infections. In Punjab, high humidity, poor hygiene awareness, excessive antibiotic use, and limited access to healthcare contributed to its widespread occurrence. Without effective prevention and management strategies, the condition significantly impacted quality of life. Addressing this issue through a public health approach was essential for reducing its …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article →
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Published Subscription Original Research
Immunological and Genetic Markers of Rheumatoid Arthritis Among Women in North India: A Case-Control StudyBy J. Samuel Kamanda, Atul Khajuria, Eric Kwasi Elliason, Stephen Monday
Abstract: Background: Rheumatoid arthritis (RA) is an autoimmune disease systemically afflicting women marked by chronic inflammation around the involved joints leading to joints destruction. It has both endocrinological and immunological associations as well as genetic associations but data pertaining to women of North India is scanty. Objective: This case-control study was done to evaluate the presence and significance of major immunological and genetic markers of RA in North Indian women with …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article →
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Published Subscription Review Article
Needle Choice in Spinal Anaesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture HeadacheBy Aniyat Ullah Sheikh, Rufaida Binta Jalal, Atul Khajuria, Deepanshu Sharma
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former's cuff to create an airtight seal. Of all the specialised masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are its four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article →
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Published Subscription Original Research
Patterns and Variations in Complementary Feeding Practices Among Mothers of Children Aged 6–24 Months Attending Immunization Clinics in Mandi Gobindgarh, Punjab, IndiaBy Eric K. Elliason, Atul Khajuria, Stephen Monday, J. Samuel Kamanda
Abstract: Introduction: Complementary feeding introduces solid or semisolid foods to an infant’s diet while breastfeeding. In India, feeding infants and young children is determined by their socioeconomic status, cultural practices, and healthcare access. The study assesses the feeding practices of mothers with children aged 6–24 months who come for immunization at Mandi Gobindgarh, Punjab. Methods: A cross-sectional study was conducted with 350 mothers selected through systematic random sampling. A structured questionnaire …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 43–53 Read article →