breast cancer
22 articles · search the full text for this term
-
Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
-
A Knowledge Graph Approach for Breast Cancer Diagnosis and Data Sharing Platform Implementation in the Context of Human Papillomavirus Infection
Abstract: Background: Breast cancer remains among the most prevalent malignancies in women worldwide, and effective diagnosis and data integration continue to challenge clinical practice. Diagnostic reports from mammography and ultrasound contain rich clinical information that is often under-utilised due to heterogeneous formats and limited data-sharing infrastructure. In the context of human papillomavirus (HPV) infection, which may influence oncogenic pathways and data complexity, advanced computational methods offer new solutions to this problem. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article
-
Sudarshan Kriya Intervention and Rise of Protective Prostaglandins in Advanced-Stage Breast Cancer: Double-Blind, Randomized, Controlled Trial
Abstract: Background: Breast cancer patients in advanced stages of cancer are managed by palliative care. This study reports important prostaglandin changes observed with added intervention of Sudarshan Kriya in their ongoing palliative care. Level of Prostaglandin A₂ (PGA₂) indicates tumor growth suppression; its level rises if person’s general condition is good, physically fit and active while PGE₂ and D₂ are considered pro-inflammatory. Quantitative assessment of Prostaglandins was done pre and post …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 62–68 Read article
-
Knowledge Enhancement Through Breast Cancer Education Among B.Sc. Nursing Students: A Pre-Experimental Study
Abstract: Background: Breast cancer continues to be a major global public health concern. Timely detection and proper management play a vital role in reducing morbidity and mortality. Nursing students must have sufficient knowledge to provide effective community education and deliver quality care. Aim: This study aims to evaluate the effect of a structured teaching program on improving the knowledge of nursing students. Method: The quantitative research approach with pre-experimental research design …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 23–27 Read article
-
Breast Cancer Detection Using Machine Learning: A Comparative Analysis of Supervised Learning Algorithms
Abstract: Globally, breast cancer remains a predominant cause of mortality among women, highlighting the urgent need for timely and precise diagnostic approaches. This research explores the application of machine learning algorithms—including Logistic Regression, SVM, Naïve Bayes, KNN, and Random Forest—on the Wisconsin Breast Cancer Dataset for effective tumor classification. Key pre-processing steps such as missing value handling, feature scaling, and dimensionality reduction were employed to improve model performance. The study evaluated …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 46–52 Read article
-
Effect of a Multi-Component Intervention on the Quality of Life of Breast Cancer Patients Undergoing Chemotherapy in a Selected Oncology Centre
Abstract: Breast cancer remains the most commonly diagnosed cancer among women globally and continues to be a leading cause of cancer-related mortality among females. In India, it has become the most prevalent cancer among women, with a noticeable rise in incidence annually. The growing burden of breast cancer highlights the urgent need for effective supportive care strategies that address not only the physical but also the emotional and psychosocial well-being of …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 11–18 Read article
-
Breast Cancer Screening Awareness and Participation Among Women in North India
Abstract: Breast cancer is the most prevalent malignancy among Indian women, accounting for 25% of all female cancers (ICMR, 2020). Significant urban-rural disparities in screening persist across North India due to socioeconomic, cultural, and healthcare access barriers. This study evaluates these disparities to inform targeted interventions. A cross-sectional study was conducted among 1,500 women (750 urban, 750 rural) in Delhi, Uttar Pradesh, Punjab, and Haryana, using stratified random sampling. Data were …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 43–50 Read article
-
Knowledge, Attitude, and Practice Regarding Breast Cancer and Its Prevention Among Adolescent School-Going Girls
Abstract: Introduction: Breast cancer claims the lives of over 500,000 women globally each year. In low-resource settings, most women are diagnosed at an advanced stage of the disease, resulting in low 5-year survival rates, typically ranging between 10 and 40%. However, in regions where early detection and basic treatment are both available and accessible, the 5-year survival rate for early-stage localized breast cancer can exceed 80%. Objectives of the Study: The …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 1–9 Read article
-
Computer Aided Diagnosis of Breast Cancer using Machine Learning Techniques
Abstract: Breast cancer is one of the significant health problems that lead to early mortality in women, especially those between 40 and 55 years of age all over the world. In recent years, the number of breast cancer cases among women has risen significantly, making early and accurate diagnosis more important than ever. Computer-aided diagnostic (CAD) tools have become valuable in supporting radiologists by enhancing the precision of breast cancer detection. …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 1–11 Read article
-
Computational Analysis of Tinospora Cordifolia Phytochemicals as Potential Inhibitors of BRCA1-BRCT Domain Interaction in Breast Cancer
Abstract: Breast cancer is a leading cause of cancer-related deaths worldwide, accounting for a significant proportion of mortality rates among women. Despite current therapeutic approaches, the disease remains characterized by molecular heterogeneity, making it challenging to develop effective treatments. This study explores the potential of Tinospora cordifolia, a medicinal plant, in breast cancer therapy. Guduchi, scientifically known as Tinospora cordifolia, boasts a centuries-long history of use in traditional medicine, with a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 27–37 Read article
-
Breast Cancer and Enhancement through Multimedia Instruction
Abstract: The health belief model served as the foundation for the study to determine the factors that most affect women's decisions to receive a breast cancer screening that examined how study participants changed after receiving a multimedia health education intervention. After that, we could create a plan to advance women's rights for the upcoming breast cancer mammograms. Following the multimedia health education intervention, the experimental group demonstrated significantly higher scores in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 35–39 Read article
-
Role of PI3K/AKT/mTOR Signaling Pathways in Breast Cancer
Abstract: Abstract: Breast cancer is among the most commonly diagnosed cancers and remains a leading cause of mortality among women globally. Although early detection and interventions aimed at curtailing tumor progression have significantly improved breast cancer survival rates, there is an ongoing demand for more potent systemic therapies to effectively prevent metastasis. A central pathway frequently associated with the growth, survival, and motility of breast cancer cells is the PI3K/AKT/mTOR signaling …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 23–34 Read article
-
Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
-
Assessing Supportive Care Needs Among Breast Cancer Survivors: A Cross-Sectional Study
Abstract: Breast cancer poses a significant global health challenge and ranks among the primary causes of cancer-related morbidity and mortality worldwide. The objective of this study was to evaluate the supportive care needs of survivors of breast cancer and examine how these needs are related to various background factors. To accomplish this, a cross-sectional study was carried out with 116 breast cancer survivors, selected using a convenient sampling method. Data were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 39–42 Read article
-
Performance Analysis of Machine Learning Algorithms For Disease Prediction
Abstract: In this 21st century, where Digitization makes humans measure, record, analyze and to manipulate the huge amount of data as per the requirement, prediction of the decease based on Machine Learning models will be representing one of the good applications of the efficient data handling. An Automatic Decease Prediction system based on the symptoms would be the great boon for the medical practitioners. The Supervised Machine Learning models, such as …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 9–18 Read article
-
Breast Cancer: Susceptible Genes and Significant Risk Factors
Abstract: Breast cancer is the most common malignancy affecting women globally. In 2012, around 1.67 million new cases were reported worldwide. With the increase in life expectancy in developed countries, the incidence of breast cancer among older adults has risen significantly. In 2017, an estimated 252,710 new cases of invasive breast cancer were recorded, along with 6,341 cases of breast cancer in situ in the USA. About 24% of all breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 36–43 Read article
-
Examining the Impact of a Nurse Navigator Program on Anxiety, Psychological Well-being, and Quality of Life in Breast Cancer Patients at a Tertiary Care Hospital in Haryana: A Randomized Controlled Trial
Abstract: Background of study: Breast cancer stands as the leading cancer type affecting women and remains a significant contributor to female mortality. It is a complex ailment influenced by multiple factors. Globally, in 2020, approximately 2.3 million women received diagnoses of breast cancer, resulting in 685,000 fatalities. This condition can profoundly impact various aspects of a person's existence, encompassing physical, psychological, emotional, social, and familial spheres. A notable observation is the …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 31–39 Read article
-
Evaluating Breast Self-examination Awareness Among Young Adult Women in Vaniyamkulam Panchayat to Create an Educational Booklet
Abstract: Introduction: Breast cancer ranks as the second most prevalent cancer worldwide and stands as the primary cancer type among women, both in developed and developing nations. It is estimated that around 25% of all cancer cases globally are attributed to breast cancer. Notably, there was a significant increase in breast cancer incidence from 2008 to 2012 on a global scale. Methods: The research utilized a quantitative methodology, employing a descriptive …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 23–30 Read article
-
Comparison of K-nearest Neighbor and Artificial Neural Network Classifiers for the Detection of Breast Cancer
Abstract: Breast cancer is the most common type of cancer seen in women in the present day, which is also considered a life-threatening disease. If this cancer can be detected in its early stage it can be a lifesaver for many people around the world. Machine Learning techniques have become one of the hotspots for predicting the early diagnosis of breast cancer. This research work experiments with the two most popularly …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 1, 2024 · pp. 78–83 Read article
-
Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article