breast cancer
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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The Practical Use of Cholesteric Liquid Crystal Film for Development of New Technologies
Abstract: The use of cholesteric liquid crystal films, using the remarkable property of cholesteric liquid crystals to change their color at the temperature changes, is well known for measuring temperature, in medicine, in jewelry and so on. The article presents the practical use of cholesteric liquid crystal films in the developed musical color device, which “animates” the pattern with a multi-colored color in accordance with the frequency spectrum of the signal …
Published in Journal of Thin Films, Coating Science Technology & Application Read article