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38 articles for “reactive oxygen species (ROS)”
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Clinical Utility of Black Tea Polyphenols in Chemoprevention and Therapeutics Against Cancer
Abstract: Tea is the second-most preferred beverage produced from Camellia sinesis. It is cultivated in more than 30 countries. Several scientific studies have specified that polyphenolic compounds in tea may reduce the risk of a variety of infirmity including cancer. Most of the research evidences are available from green tea but limited information is available from black tea. Several studies have investigated both in vitro and in vivo models including rats, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 3, 2021 · pp. 7–14 Read article
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Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article
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Rotenone Beyond Just An Insecticide: A Review
Abstract: Pesticides have received the most attention due to their global application and widespread implications on human health. In recent years, both epidemiological and toxicological studies have provided evidence that pesticides have the potential to act as toxicants contributing to the development of pathogenesis such as neuronal degenerations as well as may be utilized to induce signalling for reversal, suppress or prevent carcinogenic progression. Rotenone, an isoflavones naturally found in the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 8–13 Read article
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Effects of Cinnamic Acid and the Active Constituents of Cinnamon on Human Health and Diseases
Abstract: Free radicals can be generated continuously in the physiological process in the form of reactive oxygen species (ROS) and reactive nitrogen species (RNS). It occurs especially in the mitochondria, cytoplasm and cell membranes and plays an important role in the pathogenesis of several chronic disorders. Antioxidants can scavenge ROS and RNS and protect the cells against oxidative damage. Recently, natural antioxidants are the focus of interest because of their radical …
Published in Trends in Drug Delivery · Vol. 5, Issue 3, 2018 · pp. 5–15 Read article
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Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article
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Synthesis and Synergistic Effects of Ciprofloxacin Conjugated Zinc Oxide Nanoparticles
Abstract: Zinc oxide nanoparticles (ZnO NPs) are known as a multifunctional material because of its unique physical and chemical properties. The result of zinc oxide nano powder was characterized using various analytical techniques, such as UV-Vis spectroscopy, Fourier Transform Infra-Red (FTIR), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD) patterns. Synthesized zinc oxide nano powder was stored in dried form in the room temperature for further study. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 1, 2019 · pp. 61–71 Read article
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Eco-Friendly Synthesis of MgO Nanoparticles and Their Antibacterial Performance
Abstract: Nanoparticles (<100 nm in size) due to their enhanced surface area and high chemical reactivity have been a boon, ranging from micro to macro level. This has increased its applicability in various fields such as Food, textile, environment, biomedicine etc. Various metal oxides have been employed in Biomedical applications for their antibacterial, antioxidant and anticancerous activities. But MgO NPs have received much attention due to their high stability, non-toxicity and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 33–41 Read article
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Mannan-Rich Fractions in Poultry Nutrition: A Sustainable and Defensive Strategy against Antimicrobial Resistance
Abstract: Antimicrobial resistance (AMR) has evolved to be a significant global threat, menacing worldwide health and food security. Its proliferation in poultry farming has spurred the search for sustainable, non-antibiotic alternatives. One promising alternative is Mannan-Rich Fractions (MRFs), which is derived from Saccharomyces cerevisiae. These bioactive compounds not only support poultry health but also aid in suppressing pathogenic bacteria without contributing to resistance. This review brings together current studies highlighting how …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 1–16 Read article
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Role of Nitric Oxide in Platelets of Breast Carcinoma
Abstract: Breast cancer is a disease of multifactorial origin; it is seen frequently in women of older age, having family history, affluent society, late age of marriage and first childbirth, early menarche, late menopause, and nulliparity. Oxidative stress results when balance between reactive oxygen species (ROS) production and antioxidant defence is lost which result in mutations, sister chromatid exchanges, cytotoxicity, carcinogenesis etc. Clinical, experimental and epidemiological studies suggest that free radicals …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 25–29 Read article
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Altitude Related Variation of Antioxidant Properties of Tea Leaf (Camellia sinensis)
Abstract: Places, in the high altitude are subject to higher UV radiation as compared to places of low altitude, provided they bear the same latitudinal location. Here, in this investigation, the oxidative stress and associated cell protection in tea plants growing in Mysore (12°30′ N 76°65′ E, 770 m) and Ooty (Dodabeta – 11°4090′ N, 76°6966′ E, 2623 m) has been studied. The UV radiation varies in these two places – …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 2, 2014 · pp. 1–6 Read article
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Perspectives on ‘Kamsaharitaki’: an Ayurvedic Formulation for COVID-19 related Multisystem Inflammatory Syndrome (MIS)
Abstract: Background and Aim: Angiotensin-converting enzyme 2 receptor (ACE2), together with Transmembrane protease serine 2 (TMPRSS2), is a protein receptor for SARS-CoV-2 virus in the host subject; expression of ACE2 and TMPRSS2 reveals the multidimensional character of COVID-19 infection. SARS-CoV-2 Prominently induces pulmonary and systemic injury with other synergistic mechanisms. Preexisting chronic inflammatory conditions markedly sustain and aggravate the severity and cytokine storm. Inflammatory responses are closely linked with COVID-19 severity …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2022 · pp. 28–39 Read article
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Zn Doped CuO Nanoparticles for Increasing the Longevity of The Agricultural Products †
Abstract: Nanotechnology is an enabling technology at the service of mankind. Indeed, enhancing the long-term storage of agricultural products (post-harvest during transportation and storage) in general and apples and tomatoes, in particular, is a challenge. Zn-doped CuO is a proven nanomaterial with special ability to kill plant pathogens as well as a variety of microorganisms (bacteria, virus, and fungus). Much of the review is focused on the landmark papers published by …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 14–29 Read article
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A Comprehensive Review of Antioxidant Activity of Bhringraj (Eclipta alba) : An Indian Ancient Herb
Abstract: Eclipta alba, commonly known as Bhringraj, is an herb widely utilized in traditional Indian medicine (Ayurveda) for its diverse therapeutic properties, particularly in promoting hair growth, enhancing liver function, and improving overall health. Among its numerous biological activities, the plant’s antioxidant potential has garnered significant interest in modern phytochemistry. Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defenses, is a key contributor to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 12–21 Read article
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The potential Role of Antidepressant Medications in DNA Oxidation of Depression Disorder Cases
Abstract: Oxidative stress and DNA oxidation is a main target of different medications side effect, the current work aims to evaluate the potential role of anti-depressed medications in DNA oxidation in depression disorder cases, reactive oxygen species (ROS), total antioxidant (TAO) and 8-oxo deoxyguanine (8-oxo-dG) were detected in depressed disorder cases that treated with different medications included clomipramine, tryptizol, fluxetin, olanzapine, tryptizol with fluxetin, tryptizol with olanzapine and other types of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 41–47 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Role and impact of Dietary Antioxidants on Aging and Lifespan: A Review
Abstract: The effect of an antioxidant-rich diet on aging and lifespan has attracted significant scientific attention, primarily through the lens of the free radical theory of aging (FRTA). This theory suggests that oxidative stress caused by an accumulation of reactive oxygen species (ROS), accelerates aging and contributes to cellular damage. The accumulation of free radicals and the oxidative damage that is induced significantly contribute to the aging process. This imbalance plays …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 72–82 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
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Lipid Peroxidation in Postoperative Cases of Breast Carcinoma (Grade III)
Abstract: Breast cancer represents significant problem in the world. Oxidative modification of lipids is catalyzed by reactive oxygen species (ROS) which is known as lipid peroxidation (LPO); this changes the fluidity, permeability of membrane, cellular metabolic functions and causes derangement. Malondialdehyde (MDA) is a major end product and an index of LPO which crosslinks DNA, protein and nucleotides on the same and opposite strands. There are reports that LPO increased in …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 1, 2018 · pp. 16–22 Read article
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Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article