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19 articles for “methicillin”
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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Prevalence of Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus (MRSA) in Laboratory Environment
Abstract: Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) are widely distributed in the world and pose a major public health problem. It is one of the important organisms that are implicated in hospital acquired infections. These pathogens are responsible for morbidity and mortality especially in immunocompromised patients. In many, the organism is present as normal flora in healthy individuals. This study was undertaken to determine the prevalence of S. aureus and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 1, 2013 · pp. 39–44 Read article
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A Study on the Prevalence of Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA) on Mobile Phone Devices
Abstract: Mobile phone devices are indispensable accessories in social life used for communication. The users normally do not clean their cell phones which, therefore, serve as a reservoir of potential pathogenic bacteria. The devices are the vehicles of pathogen transmission in both health and non-healthcare settings. The presence of multiple drug-resistant strains of Staphylococcus aureus is very important as it can cause both hospital- and community-acquired infections. The present study is …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 1–6 Read article
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Exploring the Potentials of Quercetin and Kaempferol combinations along with Regular Antibiotics for the Effective Management of Methicillin-resistant Staphylococcus aureus (MRSA)
Abstract: The methicillin-resistant S. aureus (MRSA) is a bacterium that offers the challenge to numerous antibiotics which leads to a variety of problems, ranging from skin infections and sepsis to pneumonia. The natural products based management somewhat opened hope towards the betterment of the present era where the combination with currently available medicines has been studied clinically. Antibiotics (cefixime, ceftriaxone, erythromycin, ciprofloxacin, cephradine, methicillin, ampicillin, levofloxacin, and amoxicillin) and flavonoids (quercetin, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 6–9 Read article
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Methicillin Resistant Staphylococcus Aureus (MRSA) and Its Different Testing Methods: A Review
Abstract: Staphylococcus aureus, a gram-positive bacterium is a serious current health care concern. In the mid-1980s, S. aureus strains emerged that were resistant to the beta-lactamase-stable penicillin, these strains were termed methicillin resistant S. aureus (MRSA). Methicillin resistance in S. aureus is primarily mediated by the mecA gene, which codes for the modified penicillin-binding protein 2a. MRSA strain has become one of the well-known etiologic agents for a wide variety of …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 1, 2016 · pp. 27–30 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
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Prevalence and Distribution of Staphylococcus Aureus in Clinical Samples Across Age Groups
Abstract: The bacteria that cause everything from ordinary skin infections to serious illnesses is called Staphylococcus aureus. It is now known that Staphylococcus aureus may develop resistance to a variety of drugs. Staphylococcus aureus has been displaying an unusual kind of resistance to antibiotics, especially to those based on β-lactum. As a result, Methicillin Resistant Staphylococcus Aureus (MRSA) is the new name for the resistant strain of Staphylococcus aureus. The prevalence …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 15–19 Read article
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Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
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Isolation, Purification and Characterization of Antimicrobial peptide produced by Saccharomyces boulardii №6569
Abstract: Object: To identify microorganisms that are newly isolated biologically and microbiologically and determine their characteristics by purifying AMP produced by yeast. Methods: We measured the antibacterial activity of AMP using microliquid dilution and turbidity methods and purified them using membrane filtration and gel filtration methods. The molecular weight of AMP produced by Saccharomyces boulardii was measured using Acquity UPLC SQD-2 and MS. Results: We confirmed that yeast-№18, identified biologically and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 7–18 Read article
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Patient Profile and Antimicrobial Susceptibility Testingin Clinical Isolates of Staphylococcus aureus
Abstract: INTRODUCTION: Staphylococcus aureus is a gram-positive bacterium capable of causing various infections, ranging from minor skin infections to serious bloodstream infections. The rise of methicillin-resistant S. aureus (MRSA) strains has made treating these infections more challenging, as MRSA is frequently resistant to several types of antibiotics.. OBJECTIVE: The aim of this study was to investigate the patient profile and antimicrobial susceptibility patterns of clinical isolates of S. aureus in a …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 31–38 Read article
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Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
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Incidence of Community acquired MRSA in the nasal swabs of general population of Gulbarga region
Abstract: Background: Methicillin resistant S. aureus (MRSA) has emerged as a major pathogen in both community and hospital settings. Nasal carriage of S. aureus represents a major risk factor for the development of infection with this bacterium. Objective: The aim was to study community acquired MRSA incidence among nasal swabs of general population of Gulbarga. Methods: Nasal swabs from anterior nares were collected for the isolation of S. aureus from 224 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 8–13 Read article
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An Evaluation of Photodynamic Therapy in Dentistry with a Focus on Surgical Applications
Abstract: Throughout the centuries, various forms of light therapy have found applications in medical settings. These include phototherapy for neonatal jaundice, psoralen molecules combined with ultraviolet A light (PUVA) in dermatology, and techniques like photodynamic therapy (PDT) and photodetection. In recent years, the emergence of antibiotic-resistant strains, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, has necessitated the exploration of alternative treatment options. Photodynamic antimicrobial chemotherapy (PACT) has arisen as …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 3, 2023 · pp. 1–9 Read article
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Antimicrobial Activity of Partially Purified Extract of Streptomyces Sp. on MRSA
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of increasingly prevalent, difficult and expensive-to-treat nosocomial as well as community-acquired infections worldwide. Accurate and rapid detection of MRSA in a clinical laboratory is of utmost importance to avoid treatment failure as these strains are multidrug resistant and there are limited options to treat these infections. Hence, exploring newer antibacterial substances is the need of the hour. In this study, phenotypically and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 7–11 Read article
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Prevalence of Bacterial Colonisation in Patients Undergoing Hemodialysis: Experience from a Tertiary Care Centre
Abstract: Routine surveillance of patients on hemodialysis is necessary to prevent and control skin colonization and staphylococcal infections. To assess the prevalence of bacterial colonization on various skin sites in patients undergoing hemodialysis. A cross-sectional study was conducted on adult patients at a tertiary care center of North India. Study was conducted from July 2016 to September 2016 on adult patients with newly diagnosed end stage renal disease (ESRD) on maintenance …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 3, 2020 · pp. 1–9 Read article
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Antibacterial, Cytotoxicity Studies of Azukia mungo (L.) Masam and Correlation with in silico Docking Studies
Abstract: Introduction and Background: Azukia genus plants rich in proteinaceous anti-nutrients like tannins (especially condensed tannins) has been shown to have anti-bacterial activity against Staphylococcus aureus and antineoplastic activity against lung and liver cancer cells. Five types of procyanidins (condensed tannins) have already been isolated from Azukia mungo and structurally elucidated. But its activity against the Methicillin resistant Staphylococcus aureus (MRSA) has not yet been shown. Hence we focus our work …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 2, 2017 · pp. 21–31 Read article
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Isolation, Characterization and Molecular Identification of Potential Probiotic Bacterium, Bacillus amyloliquefaciens CS4 from gut of Snakehead Fish, Channa striata (Bloch, 1793)
Abstract: The present study was to isolate and characterize the potential probiotic bacterium from the gutof healthy fish, Channa striata. Totally, 37 bacteria were isolated from the gut region, in whichonly 25 isolates that showed catalase negative were selected. Among the selected isolates, CS4exhibited maximum inhibitory activity against fish (Aeromonas hydrophila, Vibrio harveyi,Vibrio parahaemolyticus) and human (Serratia marcescens) pathogenic bacteria. Theisolate CS4 exhibited potential tolerance to 0.5% bile salts at 24 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Molecular Docking Study of Curcumin-Sugar Conjugates as Cholesterol Biosynthesis as well as Staphylococcus Aureus Virulence Inhibitor
Abstract: Methicillin resistant Staphylococcus Aureus infections are the major concern in both, communities as well as in clinics. Presqualene diphosphate is the key molecule obtained from farnesyl diphosphate for the biosynthesis of staphylophyloxanthin which is responsible for the virulence of Staphylococcus Aureus as well as for cholesterol biosynthesis in humans. We designed some natural curcumin-sugar conjugates that binds to the protein associated with the formation of presqualene diphosphate and inhibit it, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 1, 2017 · pp. 15–21 Read article