Search
77 articles for “genetic basis”
-
Analysis of Genetic Basis for Morphological Variations in Normal and Tissue Cultured Plants of Andrographis paniculata in Association with or Without Arbuscular Mycorrhizal Fungi using AFLP Markers
Abstract: Andrographis paniculata Nees, a member of Acanthaceae, is one of the important medicinal herbs. The active principle, Andrographolide esters has a paramount importance in pharmaceutics. Morphological variants have been reported both in natural populations collected from various geographical areas and micropropagated plants raised through tissue culture that need to be analyzed with proper molecular tools. In order to facilitate reasoned scientific decisions on its management, conservation and prepare for a …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 1, 2019 · pp. 1–11 Read article
-
Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
-
Genetics of Bipolar Disorder: A Review
Abstract: Bipolar disorder is a complex psychiatric condition that is thought to have a significant genetic component. This article explores the genetic basis of bipolar disorder, including the potential genetic risk factors and the biological mechanisms that contribute to the development of this disorder. The article discusses the various genetic studies that have been conducted to identify genes and genetic variants associated with bipolar disorder, including genome-wide association studies (GWAS) and …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 1, 2023 · pp. 23–28 Read article
-
Laboratory Animals: Usages in Genetic Research
Abstract: Laboratory animals are one on which advanced research is conducted and validated in labs for better understanding the natural phenomenon of biological system, genetics and disease models. Laboratory animals include mice, rat, hamster, guinea pig, gerbil, monkey etc. Lab animals play a vital role in biomedical research and genetic studies as they share common physiology and genetics, which resemble to a large extent with humans and thus make them excellent …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 1, 2017 · pp. 14–21 Read article
-
Heterosis–Genetic Basis and Utilization for Improvement of Dairy Cattle: A Review
Abstract: The phenomenon in which progeny of crosses between inbred lines or purebred populations are better than the expected average of the two populations or lines for a particular trait is known as heterosis. Utilization of heterosis is the main goal of crossbreeding. The amount of heterosis maintained in a herd depends on the type of crossbreeding system selected for breeding. Heterosis includes greater viability, faster growth rate and greater milk …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 2, 2016 · pp. 40–50 Read article
-
Heterosis in Plants
Abstract: It refers to hybrid vigor or heterosis; herein, the offspring expressed better traits than one or both parent lines. This most often manifests in crop breeding as increased yield in F1 hybrids compared with their parents. Developing high-yielding hybrid cultivars across a wider range of crops represents an important strategy for addressing future food security. However, conventional hybrid breeding approaches are fraught with significant challenges in many self-pollinating crops, such …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 21–31 Read article
-
Gene Edited Livestock for Enhanced Feed Efficiency and Metabolic Adaptation Through Precision Genomic Interventions
Abstract: Advances in gene editing technologies have transformed the landscape of livestock production by enabling precise manipulation of genetic material associated with productivity, health, and environmental adaptability. Tools such as CRISPR Cas9 and emerging next generation editors allow targeted modifications that improve feed efficiency, growth performance, nutrient utilization, and stress tolerance in farm animals. This review highlights the genetic basis of feed efficiency and metabolic regulation, focusing on key genes and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
-
Bioinformatics in Veterinary Science: Unraveling Disease Patterns and Genomic Insights.
Abstract: Bioinformatics has emerged as a powerful tool in veterinary science, enabling the unraveling of disease patterns and providing valuable genomic insights. This article explores the application of bioinformatics in veterinary research, focusing on its impact on disease diagnosis, treatment, and prevention. By integrating large-scale data analysis, computational algorithms, and biological knowledge, bioinformatics has revolutionized our understanding of animal diseases, their genetic basis, and their interaction with the environment. The article …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 12, Issue 1, 2023 · pp. 21–26 Read article
-
Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
-
Beejdushti: A Conceptual Study
Abstract: The appreciation of genetic factors as arbiters of human disease is a relatively recent development in medical history. Scattered references to inheritance of biological characteristics may be found in the records of several millennia. In which comes the Ayurvedic texts. In Ayurvedic texts the genetic concept of inheritance is beautifully described in Caraka Sharir Sthan. Although Other Authors also described in direct or indirect way the genetic basis of inheritance …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 2, 2015 · pp. 48–53 Read article
-
Cancer biology and Sequencing technology: A new era for personalized patient care.
Abstract: Cancer is one of the most deadly diseases causing high mortality around the world. Lot of efforts are being made to be able to device a proper treatment for cancers. The majority treatments for various types of cancers comprise of surgery, radiation, chemotherapy, hormone therapy, immune therapy, and targeted therapy. These methods of treatment may not be fully able to get rid of cancer but able to extend the life …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 1–14 Read article
-
Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article
-
Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 · pp. 1–20 Read article
-
Immunological Mechanisms Underlying Autoimmune Disorders: Recent Advances and Therapeutic Implications
Abstract: A diverse range of illnesses known as autoimmune disorders are typified by dysregulated immune responses against self-antigens, which result in tissue damage and persistent inflammation. Understanding the genetic, epigenetic, and environmental variables that contribute to autoimmune pathogenesis has advanced significantly during the last ten years. Current disease models have been transformed by new understandings of immunological tolerance mechanisms such as the functions of regulatory T cells, cytokine networks, and the …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 21–25 Read article
-
The Future is Bioengineered: Consequences, Directions, and Regulation
Abstract: Biotechnology is changing how people interact with health, life, and the environment very quickly. This article talks about how new tools in genetic engineering, synthetic biology, and bioinformatics are making it possible for scientists to build and change biological things with more accuracy than ever before. Biotechnology is changing several fields, from making personalised medical treatments and disease-resistant crops to making biofuels and materials that break down naturally. The talk …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 40–49 Read article
-
The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
-
Breeding and Genetics of Disease Resistance in Poultry and Farm Animals: A Review
Abstract: Disease resistance is one of the most essential parameters that is now getting consideration in the animal selection along with production traits. Development and rearing of genetically disease resistant stocks is the newer face of animal husbandry at present. The increasing microbial resistance, increased drug residues in animal products, ever increasing cost of therapeutic treatment, and consumer’s preference towards organic products are all giving bright signal to the development of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 10, Issue 1, 2021 · pp. 1–7 Read article
-
Heterosis in Blackgram - History and Future Thrust
Abstract: AbstractHeterosis is the increase in vigor that is observed in progenies of matings of diverse individuals from different species, isolated populations or selected strains within species or populations. Heterosis has been of immense economic value in agriculture and has important implications regarding the fitness and fecundity of individuals in natural populations. Considering mungbean (Vigna radiata (L.) Wilczek), a pulse crop which is self-pollinated, little work has been done on heterosis. …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 2, Issue 3, 2013 · pp. 5–10 Read article
-
Breeding for Biotic Stresses Resistance in Vegetable Crops: A Review
Abstract: AbstractVegetable pests and diseases have major effect on its production. Although application of fungicides and pesticides has helped control plant diseases and insect/pests, but indiscriminate use of hazardous chemical causes environment pollution, chemical residues in vegetables above threshold levels and emergence of new races/biotypes. Therefore at this junction, breeding for the development of biotic resistant cultivars is major objective of vegetable breeder’s. Basic research on the genetic bases of pest …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 4, Issue 1, 2015 · pp. 13–27 Read article
-
A Review on Advances in Personalized Medicine: from Genomics to Clinical Applications
Abstract: Personalised medicine, also known as precision medicine, is a revolutionary approach to healthcare that customises medical interventions and treatments for individual patients according to their distinct genetic, environmental, and lifestyle properties. The basic pillar of personalised medicine is genomics, and the area has seen an explosion of genetic information with the advent of high-throughput sequencing tools. Genomic data now provide unprecedented insights into the underlying genetic variations, mutations, and genetic …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 13–17 Read article