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406 articles for “computational tools”
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Computer Programming Tool for the Design of Concrete Mixes for Pavement Quality Concrete Roads in India
Abstract: Basically concrete is a mixture of cement, sand, aggregates and water. These constituents bonds together and hardens with time and give strength to structure. The proportioning of concrete mixes consists of determining relative quantities of materials to be used. Thus to calculate proportions of various components of concrete several mix calculations are required to be performed. Consequently, it is not possible to select at once the exact mix proportion required …
Published in Trends in Transport Engineering and Applications · Vol. 4, Issue 2, 2017 · pp. 30–38 Read article
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An Introduction to Proteome Bioinformatics
Abstract: For basic and translational research, high-throughput approaches are essential. Recent improvements in proteomics techniques, for example, have allowed biomedical researchers to characterise the proteome of a variety of creatures. Proteome bioinformatics approaches and technologies have greatly aided this extraordinary progress. The study and use of informatics in the realm of proteomics is known as proteome bioinformatics. This chapter presents an overview of the computational strategies, methodologies, and techniques for bioinformatics …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 7–9 Read article
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Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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A Critical Review of Generative Design Methods in Computer-Aided Drafting
Abstract: In the realm of Computer-Aided Drafting (CAD), generative design methods have become a potential strategy for automating and enhancing the design process. These methods generate a wide range of design possibilities based on given characteristics and limitations by using algorithms and computational tools. The objective of this critical study is to assess the benefits, drawbacks, and implications of generative design techniques in CAD. A notable result of this merger is …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Computer Data Processing and Empirical Economics
Abstract: This is an article on empirical economics and computer data processing that discusses how computational technology have changed empirical research methods. It analyses how computer systems have changed data management, statistical modelling, and econometric analysis, focussing on large-scale data processing, algorithmic efficiency, and repeatability. Forecasting, policy simulation, and panel data analysis are key uses. The paper also addresses data quality, computational, and ethical issues in economic data use. The paper …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 1, 2026 · pp. 09–20 Read article
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The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Optimized Structural Design and Prototyping Techniques for Polymer-Matrix Composites in Manufacturing
Abstract: Material called polymer-matrix composites (PMCs) have become very important in modern industry because it is strong and light. To get the most out of them, structure construction must be optimized and advanced testing methods must be used. In this brief, the strategies and methods for improving the performance, lowering prices, and speeding up the production process of PMCs through structural design and prototyping are explained. Optimizing structural design starts with …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 145–161 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
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Computer Aided Drug Designing for Targeted Drug Delivery Systems
Abstract: The discovery and development of a contemporary sedate is widely acknowledged as an extremely difficult task that requires significant resources and effort. Therefore, computer-aided medication design techniques are widely utilized today to increase the productivity of the drug discovery and development process. Among structure-based and ligand-based drug design approaches, both recognized for their efficiency in drug discovery and development, various CADD (Computer-Aided Drug Design) techniques are evaluated based on specific …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 34–41 Read article
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Computer, Animation and Aesthetic Expressions
Abstract: The integration of computers, animation, and aesthetic expressions has revolutionized creative industries, enabling the development of highly immersive and visually engaging content. This interdisciplinary field combines computer science, digital animation techniques, and the principles of visual aesthetics to craft experiences that resonate with audiences on both intellectual and emotional levels. Through advanced algorithms, artificial intelligence, and innovative rendering techniques, modern animation blends technical precision with artistic design to create dynamic …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 12, Issue 2, 2025 · pp. 01–06 Read article
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Mobile Computing: Current Trends, Security Issues, and Future Directions
Abstract: Mobile computing is a rapidly emerging technology that is revolutionizing various sectors such as education, healthcare, tourism, transportation, manufacturing, banking, insurance, and hospitality. It is widely recognized as a potent computational tool that possesses the capability to profoundly influence society. By providing a mobile user with access to a wide range of information sources, the ability to exchange electronic messages, real-time interaction with other users, and the utilization of remote …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 26–30 Read article
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Emerging Digital Trends in Virology Software: Optimizing Viral Discovery, Surveillance,and Patient Management.
Abstract: Virology and antiviral therapeutics are being reshaped by rapid advances in computational tools, automation platforms, and virus-focused digital health applications. Software systems now span the entire virology value chain, from in silico viral target identification and antigen design, to AI-supported clinical trial management for vaccines and antivirals, to post-marketing pharmacovigilance and patient-facing mobile tools. This review examines current and emerging software trends relevant to virus studies, emphasizing applications in viral …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 29–38 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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3D Printing of Polymer-Based Functionally Graded Materials: Recent Developments and Challenges
Abstract: Additive manufacturing (AM), specifically 3D printing, has become a useful technique for fabricating functionally graded materials (FGMs) because it can facilitate the spatial distribution of materials. Polymer FGMs (P-FGMs) have gained a great deal of interest due to their lightweight, customizable, multifunctional properties. In comparison to conventional fabrication, 3D printing allows better control of composition and microstructure, which results in materials with controlled mechanical, thermal, and biological properties. This review …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 338–347 Read article
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Genetic Variability and Statistical Methods: Key Insights for Computational Genetics Research
Abstract: Genetic variability, defined as the differences in DNA sequences among individuals, serves as the foundation of evolutionary biology and plays a pivotal role in species’ adaptability, resilience, and overall survival. Advances in genomic technologies, particularly high-throughput sequencing, have enabled unprecedented exploration of genetic diversity, fostering the growth of computational genetics. This interdisciplinary field combines statistical methods and computational tools to analyze genetic data, identify patterns, and link phenotypes to genotypes. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 19–23 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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A Thorough Examination of the Chemical Engineering Process: Fundamentals, Design, and Application
Abstract: This article gives a full picture of the chemical engineering process, focusing on the basic ideas, methods, and tools that make up the profession. It looks at how chemical, physical, and biological processes change raw materials into useful goods, with a focus on how design, optimization, and control work together in industrial systems. Some of the main topics talked about are process design, thermodynamics, reaction engineering, transport phenomena, and sustainability. …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 14–25 Read article