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41 articles for “carcinogenic”
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Impact of Groundwater Pollution on Carcinogenic and Non-Carcinogenic Health Effects: A Review
Abstract: Groundwater is a critical source of drinking water in many regions worldwide, particularly in South and Southeast Asia, where dependence on untreated groundwater remains high. However, increasing groundwater contamination poses serious risks to human health. This review synthesizes recent peer-reviewed studies to examine the sources, distribution, and health impacts of major groundwater contaminants, with a focus on both carcinogenic and non-carcinogenic risks. Emphasis is placed on fluoride, nitrate, chromium, and …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 40–46 Read article
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Environment, Health, and Carcinogenic Concerns in the Light of Microvita Theory
Abstract: This study examines the relationship between environmental health, carcinogenic risks, and P.R. Sarkar’s microvita theory, introduced in 1986. Microvita are described as subtle entities that influence both physical and mental realms, potentially interacting with environmental factors and playing a role in health and disease, particularly in the process of carcinogenesis. By merging this philosophical concept with modern scientific insights, the study offers a fresh perspective on addressing environmental hazards that …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 2, 2025 · pp. 8–18 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Metabolic Reprogramming in Carcinogenesis: An Overview
Abstract: Metabolic reprogramming is a crucial mechanism via which cells modify their metabolic pathways to adjust to changes in the environment and maintain growth, survival, and function. This phenomenon is of utmost importance in a wide range of physiological and pathological situations, specifically in cancer, immunological responses, and stem cell biology. In cancer, metabolic reprogramming facilitates fast cell growth and survival, as demonstrated by the Warburg effect, where cancer cells prioritize …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article
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Betel Quid without Tobacco: A Threat to Oral Health and Well-being in India
Abstract: Betel quid without tobacco, a popular cultural product across India and other South and Southeast Asian nations, is often consumed for its refreshing stimulant effects during social and religious gatherings. Despite its deep cultural significance, the health hazards of betel quid – especially its strong association with oral cancers – are often overlooked. The International Agency for Research on Cancer (IARC) has identified betel quid as a human carcinogen, and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 6–16 Read article
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The implementation of the food quality protection act (FQPA) in increasing the safety standards for new pesticides used on foods
Abstract: This paper examines the Food Quality Protection Act (FQPA) and its impact on enhancing safety standards for pesticides used on food in the United States. Initially, the study explores the Delaney Clause—a strict standard prohibiting carcinogenic food additives—which FQPA replaced with a more flexible "reasonable certainty of no harm" criterion. This shift allows the Environmental Protection Agency (EPA) to assess pesticide risk with consideration of potential benefits, even if a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 41–51 Read article
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Role of Food Supplements in Premalignant Lesions: A Literature Review
Abstract: Premalignant lesions of the oral cavity are histopathological alterations in the oral epithelium linked to a higher likelihood of malignant transformation. These lesions frequently present as leukoplakia (white patches), erythroplakia (red patches), oral lichen planus, and oral submucous fibrosis. Oral cancer, categorized among head and neck malignancies, is considered the sixth most common cancer globally. While tobacco and alcohol consumption remain the primary etiological factors, increasing evidence underscores the significant …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 17–26 Read article
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Assessing the Risk of Working with Chemicals in an Automotive Unit
Abstract: Today's human life is mixed with chemicals that can affect human health independently or independently. Also, many occupational diseases are caused by chemicals. Prevention of occupational diseases caused by exposure to life chemicals It saves people and improves the quality of life of other workers. The purpose of this study is to know the risks caused by chemicals, to evaluate It is the risk of hazards and the proposal of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 3, 2024 · pp. 36–42 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Assess the Knowledge Regarding Usage of Plastic Leading to Cancer Risk and Their Preventive Measures Among House Wives in Selected Area Vaniyamkulam
Abstract: This study explores the level of awareness among housewives in Vaniyamkulam about the potential cancer risks associated with the use of plastic materials in households, along with their knowledge of preventive measures. The proliferation of plastic usage in daily life has raised significant health concerns, particularly its potential to release carcinogenic compounds such as bisphenol A and dioxins, which can leach into food and beverages. Given the critical role housewives …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 12–17 Read article
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Exploring the Genetic and Environmental Factors Contributing to Ovarian Cancer in Women in Mumbai, India
Abstract: Background: Ovarian cancer incidence in Mumbai has risen by 30% over the past decade, with an age-standardized rate of 9.1 per 100,000 women, contrasting stable trends in Western nations. This study investigates the interplay of genetic and environmental factors driving this disparity in Mumbai’s diverse population. Methods: A hospital-based case-control study was conducted at a hospital, enrolling 200 epithelial ovarian cancer cases (aged 30–70 years) and 400 age-matched controls. Germline …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 12–17 Read article
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Recent Trends in Heavy Metal Pollution of Groundwater: A Review
Abstract: Heavy metal pollution in groundwater has emerged as a major environmental and public health concern worldwide due to its persistence, toxicity, and potential for bioaccumulation. Rapid industrialisation, urban expansion, intensive agriculture, mining activities, and improper waste disposal have significantly increased the release of heavy metals into subsurface environments. Groundwater, being a primary source of drinking water in many regions, is particularly vulnerable to contamination, posing serious risks to human health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 4, Issue 1, 2026 · pp. 14–24 Read article
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Nitrosamine Accumulation, Processing Variables, and Indigenous Plant Inhibitors in Nigerian Traditionally Processed Meats
Abstract: N-nitrosamines are classified as probable or possible human carcinogens by the International Agency for Research on Cancer. Carcinogenic N-nitrosamines — principally N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) — are formed in abundance during the preparation of widely consumed Nigerian traditional processed meats including suya, kilishi, and balangu. This original investigation combined a six geopolitical zone of Nigerian market survey with laboratory-controlled model system experiments, effects of processing parameters on N-Nitrosamine formation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 61–72 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Investigations on Anthocyanin and Its Regulatory Role
Abstract: Anthocyanin is the most widely studied and abundant group of natural pigments. It has been gaining increased attention for its potential health benefits. This vibrant, water-soluble pigment is found in fruits, vegetables, and flowers, and is responsible for the colors of many of the foods we eat. Anthocyanins are not only responsible for the aesthetic appeal of these foods, but they are also believed to have powerful antioxidant, anti-inflammatory, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 32–37 Read article
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Comprehensive Review on Brake Friction Materials
Abstract: Automobile manufacturers are currently dedicated to enhancing vehicle speeds for the purpose of saving travel time. However, achieving this objective necessitates the use of friction materials capable of handling high-speed braking. In this article, we will delve into the historical evolution of materials utilized for brake pads and drums. In the past, asbestos stood out as the most widely employed brake lining material due to its effectiveness. Unfortunately, its carcinogenic …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 197–214 Read article
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Dioxin Sources, Types, Toxicity, and Removal Technologies: A Review
Abstract: This review provides a comprehensive investigation of dioxin, an endocrine-disrupting compound, and its impacts on environment and human health. Dioxin have antagonistic effects on hormones. It is pivotal to identify the origin of dioxin exposure for the well-being of environment and human health. Hence, the sources of dioxin, its dispersion, concentrations in air, water and soil medias, and health effects are discussed in detail. Endocrine disrupting compounds are categorized into …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 1, 2024 · pp. 11–19 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Investigations Into the Potential for Anthracene Decomposition of Novel Soil Bacterium, Pseudomonas putida P7
Abstract: Bioremediation of hazardous contaminants holds immense importance for the preservation of a clean and healthy environment. Conversely, the accumulation of toxicants can be mitigated with the assistance of microorganisms capable of breaking down these harmful substances into benign molecules. Anthracene is frequently used as a model molecule for studies on PAH pollution because it is found in many carcinogenic PAHs. Therefore, the hunt for new microorganisms with the ability to …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 29–44 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article