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20 articles for “and Precision Medicine: A Transformative Approach to Treatment”
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Artificial Intelligence in Early Diagnosis and Personalized Treatment of Alzheimer’s Disease
Abstract: Artificial intelligence (AI) has become a disruptive technology in the medical care industry, with potential solutions to early diagnosis and customized treatment of Alzheimer’s disease (AD), a progressive neurodegenerative disease and the most prevalent cause of dementia globally. Conventional diagnostic techniques, such as cognitive, neuroimaging and biomarker techniques, are usually limited in the ability to detect disease at its most susceptible stage when treatment interventions are most effective. The recent …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 15–27 Read article
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Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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Advancements in Nanotechnology and Biosensor Integration for Detection and Treatment of Alice in Wonderland Syndrome
Abstract: Alice in Wonderland Syndrome (AIWS) is an uncommon neurological condition characterized by profound distortions in perception. Individuals with AIWS experience altered body image and spatial awareness, often perceiving objects, surroundings, or even their own body as being unusually large, small, or distorted. The condition presents a unique challenge for both diagnosis and management due to its elusive and varied symptoms. This paper explores how advancements in nanotechnology and biosensor integration …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 1–12 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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The Impact of Artificial Intelligence on the Sales and Marketing of Pharmaceutical Products
Abstract: The rapid development of computing and technology has permeated all branches of science, with artificial intelligence (AI) emerging as a pivotal field in computer science. AI has significantly influenced disciplines ranging from basic engineering to pharmaceuticals. In healthcare and medicinal chemistry, AI applications have become indispensable. Traditional drug discovery approaches are gradually being overtaken by computer-aided drug design. In recent years, artificial intelligence (AI) and machine learning (ML) have become …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 1, 2025 · pp. 10–18 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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The Power of Genetic Engineering in Revolutionizing Vaccines
Abstract: Genetic engineering techniques, including recombinant subunit, viral vector, and nucleic acid vaccines have transformed the landscape of vaccine development. These novel approaches offer precise antigen design, enhanced safety profiles, and rapid adaptability to emerging pathogens. Key advantages include improved efficacy through targeted immune responses, increased safety due to the absence of live pathogens, and the ability to modify vaccines to address new variants or diseases quickly. Notable success stories, such …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 18–27 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article