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348 articles for “amines”
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In silico potential drug target identification against 4-aminobutyrate aminotransferase for Huntington diseases
Abstract: Huntington disease, HD is a progressive neurodegenerative disorder. Some excitatory chemicals released like glutamate which causes the cell damage and the neuron die due to over accumulation of the glutamate in Huntington diseases (HD), which is regulated by the GABA also known as gamma- amino butyric acid, it is a major inhibitory neurotransmitter of the nervous system. Here we are targeting the pyridoxal dependent enzyme which degrades the GABA neurotransmitter, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 3, 2017 · pp. 1–5 Read article
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Novel Amino Silanes for Inhibition and Dissolution of Aldol Polymer for Caustic Tower in Cracker Plant
Abstract: Aldol polymer fouling in petrochemical plant is an undesirable process, which needs to be removed for increasing the efficiency of downstream process. In this paper, inhibition and dissolution efficiency of the aminopropyl trimethoxy silane (APTMS), aminopropyl triethoxy silane (APTES), sodium salt of aminopropyl trimethoxy silane (SS-APTMS), sodium salt of aminopropyl triethoxy silane (SS-APTES) were studied at different molar ratio of vinyl acetate (VA):amino alkoxy silane (antipolymerant). The sodium salt of …
Published in Journal of Petroleum Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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PSSM Amino-Acid Composition Based Gene Identification Using Support Vector Machines
Abstract: AbstractThe main characteristic of identifying the molecular mechanism of the cell is to understand the significance or function of each protein encoded in the genome. For that purpose, genome annotation proves to be very supportive. One of the most obligatory phases of genome annotation is the prediction of the genes. Several methods or techniques have been developed in order to locate or predict the patterns of genes in genome sequence. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 6, Issue 1, 2019 · pp. 50–58 Read article
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Synthesis and Characterization of Aminophenyl (p-hydroxyphenyl)Tellurium(IV) Dichlorides
Abstract: The synthesis and characterization of a number of aminophenyl(p-hydroxyphenyl)tellurium(IV) dichlorides with the general formula RR´TeCl₂—where R stands for the p-hydroxyphenyl group and R´ denotes substituted amino aromatic moieties like aniline, N-methylaniline, and N,N-dimethylaniline—are reported in this study. Because of their distinctive structural characteristics, adaptable bonding behavior, and prospective uses in organic synthesis, catalysis, and medicinal chemistry, organotellurium compounds have garnered a lot of interest. The coordination behavior and electrical characteristics …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 2, 2026 · pp. 01–06 Read article
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Synthesis and Characterization of m-Amino Pyridine Derivatives
Abstract: Background: The current study involves the synthesis and characterization of amino derivatives. In the current research study, a series of m-amino pyridine derivatives were synthesized using m-amino pyridine and carbonyl compounds and characterized further. The pyridine derivatives have shown to possess potent antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory antidiabetic, antioxidant, anthelmintic, anticonvulsant, antituberculous and so many other properties. Method: The condensation reaction of m-amino pyridine and carbonyl derivatives with ethanol is …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 1–6 Read article
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Thermal Conductivity and Energy Storage Performance of Paraffin Wax-Based Composites Reinforced with Amine Functionalized Graphene as a Nanofiller
Abstract: In this study, amine-functionalized graphene (AFG) was employed as a nanofiller/nanomaterial to enhance the thermal and structural properties of a paraffin wax (PW)-based polymeric composite, formulated as a phase change material (PCM). The PW/AFG composite was synthesized with varying nanofiller volume fractions (0.20%, 0.40%, 0.80%, and 1.60%), and its thermal conductivity, stability, and energy storage performance were systematically analyzed. The incorporation of AFG into the polymer matrix significantly improved the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 355–374 Read article
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Removal of CO2 using Aqueous Blends of Amines by Chemical Absorption Method: Modeling
Abstract: Carbon capture from point source emissions has been recognized as one of the several strategies necessary for mitigating unfettered release of greenhouse gases (GHG's) into the atmosphere to prevent global warming. To keep the GHG's at manageable level, large decrease of CO2 should take place through capture technologies like chemical absorption. Alkanolamines such as monoethanolamine (MEA), diethanolamine (DEA), and N-methyldiethanolamine (MDEA) have been used for gas treating at industries. There …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 5, Issue 1, 2014 · pp. 1–5 Read article
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A Review on Amino Acids
Abstract: Protein is made up of amino acids, which are the building blocks of the molecule. Only 20 amino acids are involved in protein synthesis, even though more than 300 amino acids have been identified. In nature, all twenty amino acids did not appear at the same time. Rather, some of them appeared first, while others were later incorporated into the genetic code. It is vital to include them in one's …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 19–27 Read article
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Evaluation of the Formation, Concentration, and Mitigation of Heterocyclic Amines in Selected Nigerian Proteinaceous Delicacies
Abstract: This study characterised the kinetics and concentration profiles of six HCA congeners — 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (DiMeIQx), 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ), 1-Methyl-9H-pyrido[3,4-b]indole (harman), and 9H-pyrido[3,4-b]indole (norharman) — in six Nigerian food preparations (grilling of popular delicacies — including suya, kilishi, asun, and smoked catfish (eja aro)) using validated liquid chromatography–tandem mass spectrometry (LC-MS/MS) under three cooking modalities (charcoal grilling, pan-frying, oven-roasting). The inhibitory potential of five natural marinade formulations — …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 1–11 Read article
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Samarium Borohydride as Effective Reagent for Synthesis of Various Imines and Secondary Amines
Abstract: A new and economical route for the oxidative homo-coupling of benzylamines with other aryl amines, and cross-coupling of benzyl alcohol and diverse arylamines to give respective imines with a high yield, and chemo-selectivity using samarium borohydride as the catalyst in a mild condition is reported. The sequential addition of samarium borohydride in a one-pot reaction to the imines generated in situ led to the generation of a number of secondary …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 1, 2018 · pp. 21–50 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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Molecular Cloning, Expression, Purification, and Characterization of Methionine Aminopeptidase
Abstract: MAP enzyme can efficiently remove N-terminal methionine from recombinant proteins. In the present study, MAP gene from genomic DNA of Escherichia coli was amplified, cloned into pET 11b vector and transformed into E.coli DH5a cloning strain to confirm the insertion of MAP gene, then plasmid was transformed into E. coli BL21 (DE3) expression strain. The protein was eluted with 25 mM NaCl and showed a purity of ~ 95% which …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 2, Issue 2, 2012 Read article
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Biosynthesis of Amino Acids
Abstract: In this study, details of amino acids are given. Amino acids join to other amino acids and form protein. They are the ‘building blocks’ of the body. An overview of amino acid biosynthesis is given by glucose. Biosynthesis of serine from 3-phosphoglycerate and subsequent conversion of serine into glycine is explained with the diagram. General properties of amino acids are also given in this study. Keywords: Amino acids, building blocks, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 1, 2017 · pp. 1–8 Read article
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Aceclofenac and Diclofenac Sodium Conjugates with Amino Acids to Overcome Acidity
Abstract: This research work was based on a conjugate approach with some non-steroidal anti-inflammatory drugs (NSAIDs) to overcome the side effects like gastric irritation, solubility behavior, and some other effects of NSAIDs. Almost all the NSAIDs have undesirable reactions as well as they cause some types of major adverse reactions. Here the prodrugs conjugates are the approaches that increase the lipophilicity of the drug and decrease the solubility in water by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 19–25 Read article
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Synthesis, Characterization and Antibacterial Activity of Mono- and Binuclear Co(II) and Cr(III) Mixed-Ligand Complexes Derived from α-Amino Acid and 1,10- Phenanthroline with 1,3-Diaminopropan as a Spacer
Abstract: Mixed-ligand complexes of Co(II) and Cr(III) ions were synthesized from the reaction of metals chloride salts with α-amino acid (H2L1) as a primary ligand and 1,10-phenanthroline (L2) as secondary ligand. The ligand 2-(benzo[d]thiazol-2-ylamino)-2-(2-hydroxynaphthalen-1-yl) acetic acid (H2L1) has been synthesized from the condensation reaction of inobenzothiazol with 2-hydroxy-1-naphthaldehyde in the presence of HCN as three components–one pot reaction. H2L1 considered as a tridentate chelater of ONO-coordination binding type toward the metals, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 107–120 Read article
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Development and Evaluation of a Cost-Effective UV-Protective Cream Containing Para-Aminobenzoic Acid and Aloe Vera for Indian Climatic Conditions.
Abstract: The increasing incidence of ultraviolet (UV) radiation-induced skin disorders has heightened the demand for effective, affordable photoprotective agents, especially in countries with high sun exposure such as India. This study aimed to develop a cost-effective and efficient UV-B protective cream formulation suitable for populations in Indian latitudes. Para-aminobenzoic acid (PABA) was selected as the primary sunscreening agent due to its high UV-B absorption efficiency, low toxicity, and affordability compared with …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 7–18 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article
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A Forensic Study on Serum Leucine Aminopeptidase Activity Alteration in Carbon Monoxide Poisoning
Abstract: Background: Recently, Carbon Monoxide poisoning is diagnosed medicolegally depended on poison analytic chemistry and not in biochemical method. Methods: This essay was confirmed the activation change of LAP in Carbon Monoxide poisoning. The LAP activation level was higher than normal in a death with CO poisoning. Because of the Carbon Monoxide poisoning, patients were admitted to the hospital and were cured during a certain period of time. After that, the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 71–75 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
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Optical Absorption and Electronic Properties of 4-Aminoantipyrine Schiff’s Bases: A Combined Experimental and DFT Study
Abstract: The Schiff base compounds (A1–A9) have been synthesized and characterized by elemental analysis, FT-IR, UV-Vis, mass spectrometry, 1H-NMR and 13C-NMR. Electronic absorption spectra of A1–A9 are studied in various solvents with different polarity like hexane, chloroform, methanol and dimethyl sulfoxide. To support and better understanding of experimental results, density functional theory (DFT), time dependent density functional theory (TDDFT) calculations has been carried out for these molecules and are in good …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 8, Issue 1, 2017 · pp. 1–13 Read article