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16 articles for “alkaline phosphatase”
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Seroprevalence of Hepatitis E Virus and Serum Level of Serum Aspartate Transaminase (AST) and Alkaline Phosphatase (ALP) Among Jaundice Patients in Kathmandu Valley, Nepal
Abstract: Hepatitis E is an acute disease caused by hepatitis E virus that usually manifest as acute jaundice. It is a waterborne infection and occurs sporadically or as epidemic outbreaks. Hepatitis E virus (HEV) is a positive-stranded RNA virus with a 7.2 kb genome with three open reading frames In this study we report the seroprevalence of HEV in different categories of jaundice patients along with their elevation of serum bilirubin, …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 37–42 Read article
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Sublethal Toxic Effect of Paraquat Dichloride on Tissue Biochemical Markers in Labeo rohita
Abstract: The present study investigated the sublethal toxic effect of the commercial grade herbicide, Paraquat dichloride (24% SL), on Labeo rohita stressing the importance on biochemical parameters. Fishes were exposed to the sublethal concentrations of paraquat dichloride (5 μg/l and 10 μg/l) for 24 h in treated groups. Treated groups showed highly changed biochemical parameters on their exposure to the herbicide paraquat, when compared to the control. Tissues such as brain, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 2, 2021 · pp. 20–28 Read article
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Status of Phosphatases in Basella alba L. Leaves During Water Stress
Abstract: Activity of acid phosphatase and alkaline phosphatase in the leaves of medicinally important plant Basella alba with respect to its two cultivars under water deficit and water logging stress was estimated. It was recorded that the activity of both the phosphatases increased with increase in water stresses with single exception. The increased activities probably help in release of inorganic phosphates at intracellular level that might regulate proper plant metabolism which …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 1, 2016 · pp. 6–9 Read article
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Effects of Plasticizer DI-(2 Ethylhexyl) Phthalate on Liver Enzymes of Adult Male Albino Rats
Abstract: AbstractDi-(2 Ethylhexyl) Phthalate (DEHP) is a common plasticizer used to make the plastic products more flexible. It is quite harmful as tested on other animal models and is carcinogenic too. The liver is the major organ for detoxification in body and is therefore affected first due to intake of any toxicant. The liver enzymes are good parameter to assess any such hepatic damage. In the present study, the acute toxicity …
Published in Research & Reviews : Journal of Ecology · Vol. 6, Issue 2, 2017 · pp. 6–9 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Toxicological and Pharmacological Effect of Khadirarista in Animal Model
Abstract: AbstractThe objective of this study is to investigate the toxicological and pharmacological aspects of the popular Ayurvedic preparation Khadirarista (KDR). Khadirarista was administered orally to male albino rat. After 46 days of treatment period, animals were fasted for 18 h after the last administration. Biochemical studies including; total protein, serum albumin, blood urea nitrogen, bilirubin, creatinine, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase were conducted. Triglyceride and creatinine levels were …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2013 · pp. 61–67 Read article
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Mucosal Vaccines in Fish: Novel Advances in Technology and Delivery: A Review
Abstract: Vaccines rely on the acquired immune system and prime an animal to a particular antigen so that on subsequent encounter; it is recognized and quickly destroyed. The vast majority of pathogens enter the body via the mucosal surfaces of the gastrointestinal, respiratory, and urogenital tracts, where they initiate mucosal infections that lead to systemic infections. There is strong evidence that an optimum mucosal immune response can prevent systemic infection and …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 14–26 Read article
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A Clinical Study based Observation on Prevalence of Altered Liver Enzymes among Patients of Hepatobiliary Diseases Attending National Institute of Unani Medicine, India
Abstract: Background: Hepatobiliary disease is a major health problem responsible for millions of deaths annually. As reported, more than 40 million deaths occur annually in South-East Asia Region due to hepatobiliary diseases. This study was conducted as a clinical trial to assess the efficacy of Unani formulation, from which the data on prevalence of altered liver enzymes among patients of hepatobiliary diseases in which the study participants were collected and compiled …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 5–11 Read article
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Ameliorating Effect of Vitamin C on Acid Orange 7 Induced Oxidative Stress in the Gill of the Fish, Anabas testudineus (Bloch, 1792)
Abstract: Acid orange 7, an azo dye, was exposed to Anabas testudineus at a sublethal concentration (0.27 g/l) for 24, 72 and 96 h in order to evaluate the antioxidant status in the gill tissue. In addition, vitamin C at 0.55 g/l was exposed for 7 days after the dye exposure. Acid orange 7 decreased the body weight of fish, whereas mucous deposition increased significantly as the first line of defensive …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 15–27 Read article
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Hepatoprotective Efficiency of Nigella sativa L. Extract on D-Galactosamine Induced Toxicity
Abstract: The Protective role of Nigella Sativa L. alcoholic extract (NSE) was investigated on D-Galactosamine (DGalN) induced hepatotoxicity in rats. Twenty four adult wistar albino rats were divided into four groups viz Control, D-Galatosamine induced hepatotoxicity, Nigella sativa alcoholic extract and Nigella Sativa alcoholic extract pretreatment prior to the administration of D-Galactosamine. After treatment, the rats were sacrificed, blood and liver samples were collected for determination of Serum Aspartate transaminase (AST), …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 39–44 Read article
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Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Occupational Hepatocellular carcinoma : A review
Abstract: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths. The relationship between occupation and liver cancer has not been extensively studied however. Approximately 80% of HCC patients have had an established history of chronic liver disease and infection with hepatitis B virus (HBV) and hepatitis C virus (HCV). Nonalcoholic steatohepatitis (NASH), obesity, diabetes and smoking also increase the risk of HCC development significantly. Currently, only vinyl chloride monomer …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 1, 2011 · pp. 98–106 Read article
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The Significance and Correlation of Biochemical Parameters-related to Bone Diseases
Abstract: The chemical composition, mass and property of bones are controlled by various factors which include decreased mineral intake or absorption, defects in Vitamin D absorption or activation. Bone diseases are also influenced by growth factors, estrogen, testosterone, insulin, Parathyroid, Thyroid, and Cortisol hormone. Our study handles various human blood and urine samples ranging between the ages of 25–50 years for the above mentioned parameters which include calcium, alkaline phosphatases, phosphorous, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 33–36 Read article
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Hematobiochemical Alteration in Naturally Infected Cattle with Fasciola under Tropical Region
Abstract: Fascioliasis is among one of the emerging and re-emerging disease which has zoonotic importance and spread by feco-oral route. The migrating fluke causes extensive liver damage results in economic burden to the animal farmer. In present investigation 20 cattle were used to evaluate the hemato-biochemical alteration in naturally acquired fasciola infection and without other diseases. Decreased Hemoglobin, Packed cell volume (PCV), Red blood cells (RBC) count whereas; an elevated level …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 1, 2015 · pp. 20–23 Read article
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The role of Ethylacetate fractions of Parkinsonia aculeata and Newbouldia laevis against Carbon Tetrachloride Toxicity in Rats
Abstract: This research work studied the preventive effect of ethylacetate fractions of Parkinsonia aculeata and Newbouldia laevis using carbontetrachloride (CCl 4 ) model to induce toxication in rats. Increased (p<0.05) serum concentrations of enzymes and non-enzymes biochemicalparameters such as lactate dehydrogenase, gamma glutamyl transferase, alkaline phosphatase, alanine and aspartate transaminases andtotal bilirubin, were seen in group of rats administered only carbon tetrachloride. However, groups that received 100 to 200mg/kg of thetwo …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 39–50 Read article