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5 articles for “acid reflux”
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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An Efficient Synthesis of Some Novel Benzo Coumarin Derivatives Under Solvent Conditions from 2-acetyl-benzo[f]chromen-3-one
Abstract: The synthesis of the target compounds began with the preparation of 2-[3-dimethylamino[acryloyl-3H-benzo[f]chromen-3-one. This intermediate was obtained through the reaction of 2-acetylbenzo[f]coumarin-3-one with N,N-dimethylformamide dimethyl acetal [DMFDMA[ under reflux conditions in xylene. The enaminone thus formed was subsequently reacted with 6-aminothiouracil in acetic acid, leading to the formation of 2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one. This compound served as a pivotal intermediate for the synthesis of a series of pyridotriazolopyrimidinones. These derivatives were synthesized by reacting …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 33–46 Read article
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Unraveling Ulcerogenesis: A Comprehensive Delve of Enteric & Nonenteric Ulcers
Abstract: Enteric ulcers present a multifaceted landscape encompassing both peptic and non-peptic varieties, demanding a thorough exploration of their manifestations, causes, and pathophysiology. At the forefront of understanding lie pivotal factors such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs usage, lifestyle choices, and stress, each wielding significant influence over ulcer development and progression. The intricate interplay of these factors underscores the complexity of enteric ulcer etiology. Helicobacter pylori infection—a prevalent culprit—inflicts …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 25–40 Read article