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37 articles for “Vitamin D metabolism”
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Maternal and Fetal Consequences of Vitamin D Deficiency during Pregnancy: An Overview
Abstract: Apprehensions exist about the adequacy of vitamin D in pregnant and lactating women. Maternal vitamin D status influences maternal, fetal, and breast-fed infant bone health; maternal adverse outcomes (bone health, gestational diabetes, obstructed labor, preeclampsia, and infectious disease); fetal adverse outcomes (growth, bone health, gestational age, intrauterine growth, type 1 diabetes, asthma, immune development and cardiac disease); and infant adverse outcomes. Throughout pregnancy, maternal vitamin D standing may be of …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 12–28 Read article
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An Approach towards in Management of Chronic Kidney Disease
Abstract: The current international guidelines define and classify the chronic kidney disease (CKD) as decreased kidney function shown by decreased glomerular filtration rate (GFR). Glomerular filtration rate of 60 ml/min/1.73 m 2 for at least 3 months is a marker for kidney damage. The underlying causes for chronic kidney disease are proteinuria and hypertension. It is the main cause of CKD in many high-, middle- and low-income countries. In different countries, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 9–15 Read article
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Correlation of Serum Vitamin D Levels with Insulin Resistance in Young Adults
Abstract: Among young adults, both insulin resistance (IR)and vitamin D deficiency are common and pose the risk of complications, such as type 2 diabetes mellitus (T2DM). A few studies demonstrated that vitamin D deficiency might negatively influence insulin sensitivity, but the results of these studies have been inconsistent and/or inconclusive. This review focuses on young adults and aims to summarize and critique studies that assess the relationship between IR and serum …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 69–74 Read article
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A narrative review on cardiovascular disease due to the role of deficiency of Vitamin D and its management
Abstract: Cardiovascular disease is the prevalent cause of morbidity and mortality in the world, affecting many millions of individuals every year. Atherosclerosis, a chronic inflammatory condition that involves different cell types, several cytokines and adhesion molecules, is the underlying cause of cardiovascular disease. Vitamin D plays a pivotal role in bone homeostasis and calcium metabolism. Though, current research has specified additional helpful effects of vitamin D on the cardiovascular system. Vitamin …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 9–20 Read article
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A Critical Review of Vatavyadhi and Basti Chikitsa with Special Reference to Musculoskeletal Disorders
Abstract: Introduction: Musculoskeletal disorders (MSD) include any injury or damage of muscles, nerves, tendons, joints, etc., when under any circumstances these tissues work harder or get stretched beyond their normal limits or when they are used inappropriately (overuse) leading to fatigue of the tissues as well as the body. In Ayurveda the term Musculoskeletal disorders can be correlated to the Nanatmaja Vikaras of Vata-Vatavyadhi (for eg, SandhigataVata, Avabahuk, Gridrasi, etc.) which …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2022 · pp. 10–17 Read article
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The Multifaceted Vitamin B6: Metabolism, Cardiovascular Health, Cognition, and Cancer
Abstract: Vitamin B6 is hydrophilic and plays a crucial role in various metabolic processes. It acts as a cofactor in different enzymatic reactions. Vitamin B6 exists in various forms, including pyridoxal 5'-phosphate (PLP), the most active form. Vitamin B6 is essential for amino acid metabolism, such as PLP is essential for transamination, the process of transferring amino groups between amino acids. This is vital for synthesizing non-essential amino acids and breaking …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 33–39 Read article
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Nutrient–Xenobiotic Crosstalk in Dairy Cattle: Implications for Metabolism, Immunity, Health, and Productivity in Resilient Dairy Development
Abstract: Dairy cattle are routinely exposed to a wide range of xenobiotics, including mycotoxins, heavy metals, pesticides, residues from veterinary drugs, and plant secondary metabolites, through feed, water, and environmental sources. These xenobiotics, being foreign to biological systems, can interfere with the absorption, metabolism, and utilization of essential nutrients, while also compromising immune function, organ health, and overall physiological performance. Chronic or subclinical exposure can reduce feed efficiency, disrupt energy and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 37–46 Read article
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Assessment of Vitamin D Levels Among Hashimoto and Hypothyroidism Disease in Iraq, A Comparative Study
Abstract: The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 77–83 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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A Comprehensive Review of Nutritional Supplements
Abstract: The role of nutrition and nutraceuticals in human health and disease, covering macronutrients, micronutrients, organic acids, trace and macro minerals, vitamins, and bioactive compounds. It outlines biochemical structures, dietary sources, metabolism, physiological functions, and deficiency states of carbohydrates, proteins and amino acids, and fats. Key organic acids, choline, and taurine are described for their metabolic and digestive roles. The document evaluates dietary supplements, functional foods, nutraceuticals, designer foods, and medicinal …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 40–81 Read article
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High Doses Biotin beyond Its Nutraceutical Prescription: Update Indications for Neurological Diseases
Abstract: Biotin or vitamin H is ubiquitous B-complex vitamin that plays as a co-factor in different metabolic process in the body. The usual recommended daily requirement is 30µg. Recent studies found biotin in high doses involved in the synthesis of myelin in patients with multiple sclerosis. The Med Day Pharmaceuticals launched an oral formulation of biotin high dose (Cerenday 100 mg capsule) and recommended for multiple sclerosis. Previous studies demonstrated the …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 2, 2017 · pp. 13–20 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Non-alcoholic fatty liver disease (NAFLD) affects about one-third of the population in the United States and Western countries, reaching up to 90% among obese individuals and those undergoing bariatric surgery. Characterized by hepatic fat accumulation, NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and, in rare cases, hepatocellular carcinoma. Linked intricately with metabolic syndrome, including diabetes and obesity, NAFLD development involves insulin resistance and hyperinsulinemia. Experimental evidence consistently …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 Read article
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Rethinking Functional Dairy Foods: A Deeper Dive into Nutrition, Resilience, Cognitive Skill, and Healthy Ageing Across the Lifespan
Abstract: Dairy products have long been recognized as fundamental components of a balanced diet, providing essential nutrients that support overall health, well-being, and longevity. This study explores the role of dairy consumption in promoting sustainable nutrition, enhancing life expectancy, and maintaining a healthy lifestyle. Dairy foods – such as milk, yogurt, and cheese – are rich sources of high-quality protein, calcium, vitamins, and bioactive compounds that contribute to bone health, cardiovascular …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 15, Issue 2, 2026 · pp. 50–68 Read article
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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Millet Bran: Unveiling Its Potential Health Benefits
Abstract: Millet bran, derived from various millet grains, has emerged as a potent nutritional source, rich in fiber, vitamins, minerals, antioxidants, and omega-3 and omega-6 fatty acids. Its rising popularity is driven by its gluten-free nature, nutrient density, and sustainability. This review aims to explore the potential health benefits of millet bran, focusing on its digestive health, blood sugar control, heart health, antioxidant properties, and fatty acid composition. The Millet brand …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 11–19 Read article
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Fungal-derived Nutraceuticals & Bioactive Compounds with Physiotherapeutic and Health- promoting Properties: A Comprehensive Review
Abstract: Fungal-derived nutraceuticals represent a rapidly expanding field in biomedical research, offering a rich source of bioactive compounds with diverse therapeutic applications. This comprehensive review examines the physiotherapeutic and health-promoting properties of fungal metabolites, including polysaccharides, terpenes, proteins, peptides, alkaloids, fatty acids, vitamins, and minerals. Fungi produce over 9,000 bioactive compounds from approximately 22,500 microbial metabolites, with less than 5% of the fungal kingdom explored [1] . The major bioactive constituents …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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The New Dimension of Cancer: It is Not a Disease but a Deficiency of Vitamin B17
Abstract: Most commonly used an alternative drug in the treatment of tumor in the last 40 years is Amygdalin. Treatment based on the use of Vitamin B-17, proteolytic pancreatic enzymes, immunostimulants, vitamin and mineral supplements for cancer is a metabolic therapy which is nontoxic. National Cancer Institute is unsuccessful to prove that Laetrile is ineffective and toxic during their studies by clinical trials in 1981. Today, position on the "front lines" …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 3, 2018 · pp. 34–36 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 84–97 Read article