Search
16 articles for “Vancomycin”
-
Study of the Antimicrobial Potential of Consortiums of Hot Alcoholic Extract of Plants against Multidrug Resistant Bacteria Including One Vancomycin-Resistant Staphylococcus aureus (VRSA)
Abstract: Increasing antibiotic resistance exerts threatening implications in human health care. It subsequently increases the need to develop an alternative strategy to counter the growing concern against the superbug infection in open wounds. In the present study, two combinations of herbal alcoholic extracts have been assessed for antimicrobial activity against the isolates collected from human burn wound sample and biopsies. Total of 42 strains have been isolated and screened for its …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 18–25 Read article
-
Formulation of Vancomycin Capsules and Characterization of Related Substances
Abstract: Aim of this research work was to develop vancomycin capsules and analysis of the related substances which was performed using HPLC and mass spectrometer. The impurities present in the formulation were identified and the two unknown impurities present at RRT about 0.65 and 2.10, were isolated, purified and characterized. The first impurity was found to be a polar substance and it was found to arise due to the amide cleavage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 42–51 Read article
-
In silico Bioprospection and Identification of Propitious Herbal Mitigators Against Highly Virulent Pathogenic Strains of Bacteria Like Vancomycin Resistant Enterococci
Abstract: Vancomycin resistance genes have been isolated from various strains of Enterococci, owing to the high rate of recombination and vast potential of disseminating resistant genes between Enterococcal strains. Various virulent factors contribute towards the dissemination of infections caused by such Multi-Drug Resistant (MDR) strains, ultimately leading to a devastating state of environmental contamination and cross infection. Minimizing the prevalence of these strains by multiple control efforts therefore is of paramount …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 1, 2015 · pp. 1–14 Read article
-
Evaluation of Some of the Antibiotics in the Management of Hepatic Encephalopathy (HE): An Overview
Abstract: Hepatic encephalopathy (HE) is a common complication among patients with liver cirrhosis associated with a high mortality rate. It is marked by fluctuating neuropsychiatric and cognitive impairment, which can be severe and life threatening. Liver cirrhosis is a leading cause of morbidity and mortality worldwide but exact prevalence of cirrhosis is not known. Prevalence of HE, also known as portosystemic encephalopathy (PSE), is 24% in cirrhotic patients. The diagnosis remains …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 3, 2020 · pp. 22–39 Read article
-
Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
-
An Evaluation of Photodynamic Therapy in Dentistry with a Focus on Surgical Applications
Abstract: Throughout the centuries, various forms of light therapy have found applications in medical settings. These include phototherapy for neonatal jaundice, psoralen molecules combined with ultraviolet A light (PUVA) in dermatology, and techniques like photodynamic therapy (PDT) and photodetection. In recent years, the emergence of antibiotic-resistant strains, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, has necessitated the exploration of alternative treatment options. Photodynamic antimicrobial chemotherapy (PACT) has arisen as …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 3, 2023 · pp. 1–9 Read article
-
Patient Profile and Antimicrobial Susceptibility Testingin Clinical Isolates of Staphylococcus aureus
Abstract: INTRODUCTION: Staphylococcus aureus is a gram-positive bacterium capable of causing various infections, ranging from minor skin infections to serious bloodstream infections. The rise of methicillin-resistant S. aureus (MRSA) strains has made treating these infections more challenging, as MRSA is frequently resistant to several types of antibiotics.. OBJECTIVE: The aim of this study was to investigate the patient profile and antimicrobial susceptibility patterns of clinical isolates of S. aureus in a …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 31–38 Read article
-
Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting
Abstract: Neonatal sepsis is one of the most important causes of infant mortality and morbidity. In spite of availability of broad spectrum antibiotics, treating sepsis has become a challenge due to emergence of resistant strains from time to time. The present study is aimed at to isolate the organisms causing sepsis in neonates and their antibiotic susceptibility patterns. From April 2013 to June 2014, 167 blood samples were collected from clinically …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 11–15 Read article
-
Isolation and Identification of Bacteria Causing Chronic Suppurative Otitis Media and Its Antibiogram
Abstract: Background: Chronic Suppurative Otitis Media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity, which presents with recurrent ear discharge or otorrhoea through a tympanic perforation. According to WHO, the prevalence of CSOM in India is more than 4% and it falls among those countries where urgent attention is needed. It can be caused by various bacteria, fungus and viruses. Bacterial origin of CSOM is more common …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
-
Antibiotic Susceptibility of Lactic Acid Bacteria and Bifidobacteria
Abstract: Three Lactobacillus (LAB) strains, namely, LAB-3, LAB-11 and LAB-21 (species L. casei) and three Bifidobacteriam (BB) strains, namely, Bifi-11, Bifi-19 and Bifi-20 (species B. infantis) were grown in MRS broth and TPY broth, respectively. They were subjected to susceptibility tests against a range of antibiotics. The isolates were resistant to streptomycin, vancomycin, bacitracin, cephalothine, ceftizoxime, ceftriazon, cloxacillin, clindamycin, cefuroxime, cefuxime and tetracycline and kanamycin but susceptible to ampicillin, amoxicillin and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 2, 2014 · pp. 7–14 Read article
-
Synergistic Antimicrobial Efficacy of Tazma (Melipona Spp.) and Bee (Apis Mellifera) Honey with Garlic (Allium Sativum) Against Multidrug Resistant Pathogenic Clinical Bacteria
Abstract: Investigation on the search of alternative medicine is crucial where there is development of resistance against commercial antibiotics. The main objective of this study was to investigate antimicrobial activity of tazma and bee honey in combination with garlic against multidrug resistant pathogenic bacteria. Antimicrobial activities of test samples against standard and multidrug resistant bacteria were evaluated. Vancomycin was used as positive control. Minimum inhibitory and bactericidal concentrations of samples were …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 3, 2014 · pp. 10–17 Read article
-
Existence of Integron I and II Genes from Clinical Isolate Staphylococcus aureus and Their Role in Drug Resistance
Abstract: An integron is a gene capture and dissemination system. They have been identified on both genomic and mobile genetic elements which often contain one or more genes that encode antibiotic resistance. They are commonly associated with bacterial genera in the family of Enterobacteriaceae. Currently, there have been recent reports showing the presence of integrons in Staphylococcus species. The aim of the present study was to assess the existanxe of Class …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 3, 2014 · pp. 18–24 Read article
-
Bacteriological Profile and Antibiogram Pattern in Lower Respiratory Tract Infection in Kota Region (Raj)
Abstract: Lower respiratory tract infections are the most frequent infections among patients. The consequences on increased drug resistance are far reaching, since bacterial infection of the lower respiratory tract is a major cause of death from infections disease. This study was focused on obtaining a comprehensive insight into the microbial profile, its prevalence and the antibiotic susceptibility patterns of the isolates in lower respiratory tract infections. Sputum specimens were collected from …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 13–17 Read article
-
Study of Aerobic and Anaerobic Bacteriological Profile in Patients Presenting with Ear Discharge and Antimicrobial Susceptibility Pattern of Aerobic Isolates
Abstract: Ear discharge is a major health problem in both, developed and developing countries. This study was undertaken to determine the pattern of the different etiological aerobic and anaerobic bacteria in patients presenting with ear discharge and clinically diagnosed as CSOM and ASOM and also to know the antibiogram of aerobic bacteria in Kota Rajasthan. A prospective study was carried out in department of microbiology, MBS Hospital, Kota, among 100 patients …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 23–30 Read article
-
Bacteriological and Yeast Profile in Clinical Samples from Immunocompromised Persons (Especially in HIV and Cancer Patients) and Their Antimicrobial Susceptibility Pattern
Abstract: AbstractImmunocompromised host describes a patient who is on increased risk to acquire infection due to congenital or acquired abnormality of the immune system. In the past few decades, the population of immunocompromised hosts has expanded enormously, due to the increased use of immunosuppressive conditions like HIV, cancer, etc. This study was planned to know the spectrum of organisms and trend of antimicrobial susceptibility pattern in immunocompromised patients. All hospitalized patients …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 1, 2017 · pp. 1–8 Read article
-
Isolation, Characterization and Molecular Identification of Potential Probiotic Bacterium, Bacillus amyloliquefaciens CS4 from gut of Snakehead Fish, Channa striata (Bloch, 1793)
Abstract: The present study was to isolate and characterize the potential probiotic bacterium from the gutof healthy fish, Channa striata. Totally, 37 bacteria were isolated from the gut region, in whichonly 25 isolates that showed catalase negative were selected. Among the selected isolates, CS4exhibited maximum inhibitory activity against fish (Aeromonas hydrophila, Vibrio harveyi,Vibrio parahaemolyticus) and human (Serratia marcescens) pathogenic bacteria. Theisolate CS4 exhibited potential tolerance to 0.5% bile salts at 24 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article