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143 articles for “Type 2 diabetics”
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β-cell Deficit Due to Increased Apoptosis Islet Cell Plasticity in Humans Type 2 Diabetes
Abstract: Beta cells (β cells) in the pancreatic islets produces insulin and the number of functional insulin-producing β-cell contributes to the pathophysiology of type 2 diabetes . Type 2 diabetes is a chronic disease characterized by the deficiency in β-cells and increase in the levels of sugar in blood. β cells promote inflammation in obesity and type 2 diabetes. The low β-cell accumulation in Type 2 diabetes paves way to diabetes …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 1–7 Read article
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A summary continuation analysis evaluating the prevalence and predictors of diabetic retinopathy in newly diagnosed type 2 diabetic patients.
Abstract: Context: Diabetic retinopathy (DR), the leading cause of acquired blindness in adults, affects approximately 93 million people globally. It is a serious complication of type 2 diabetes, resulting from prolonged damage to the blood vessels in the retina. Although largely preventable and treatable, DR continues to be the main cause of vision loss among working-age adults and significantly impacts quality of life. While most studies on DR in Nepal have …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 21–30 Read article
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Type 2 Diabetes Mellitus: Existing Understanding and Expectations in India
Abstract: Increased fracture risk, which has been connected to type 1 diabetes in the past, has now become a top concern for those with type 2 diabetes. Depending on where the bone is located, how long you've had diabetes, and the study techniques, there has been evidence of a varying increase in fracture risk, ranging from 20% to 3-fold. An increased risk of fracture has been associated with a longer disease …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 12, Issue 3, 2022 · pp. 12–17 Read article
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Comparison of Prescribing Pattern of Anti-hypertensive Drugs and the Level of Control Achieved in Type 2 Diabetes Patients between Primary and Tertiary Care Hospitals
Abstract: Hypertension is a common co-morbidity of diabetes affecting majority of people with diabetes, also a major risk factor for coronary vascular disease and microvascular complications such as retinopathy and nephropathy. To compare prescribing pattern of anti-hypertensive drugs and the level of control of hypertension achieved in type 2 diabetes patients in primary and tertiary care hospitals. Fifty patients each with type 2 diabetes and hypertension (fulfilling JNC 7 criteria for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 2, 2014 · pp. 1–4 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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Impact of PPAR-γ2 pro12Ala Gene Polymorphism and Susceptibility of Type 2 Diabetes Mellitus in Patients Visiting Gondar University Teaching Hospital
Abstract: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia that can occur through mechanisms such as; impaired insulin secretion, insulin resistance in peripheral tissues and increased glucose output by liver. Type 2 diabetes clearly represents a multifactorial disease, and several findings indicate that multiple genetic and environmental factors are important contributing factor involved in the pathogenesis of this disease. Recently great emphasis has been given to genetical factors to combat …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 2, 2015 · pp. 21–28 Read article
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Prevalence of Oral Candidiasis by Candida albicans in Patients with Type 2 Diabetes Mellitus Visiting Mahakali Zonal Hospital
Abstract: Patient with type 2 diabetes mellitus are at consistent risk of oral candidiasis, dental caries and dysfunction. Candiadisis is caused by different species such as Candida albicans, C. tropicalis, C. glabrata, C. dubliniensis. Nevertheless, C. albicans is the most frequent causative agent for candidiasis in human. Present work was undertaken to investigate Candida albicans infection among type 2 diabetic mellitus patients in Mahendranagar, Kanchanpur. Methods: A total of 103 oral …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 1, 2020 · pp. 1–5 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients.Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, IL-4, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Clinical Evaluation of Naqooh Shahtara in the Management of Type 2 Diabetes Mellitus
Abstract: Diabetes is a major public health problem and considered as one of the most common non-communicable disease, globally. Although the prevalence rate of the disease varies country to country. However, WHO has projected India as the country with the fastest growing population of diabetes patients. Due to its consequences diabetes has become a silent killer that kills one person every 10 seconds, and worldwide it kills 3.2 million every year. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2016 · pp. 32–37 Read article
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Screening of Mean Platelet Volume as a Prognostic Marker in Patients with Type 2 Diabetes Mellitus
Abstract: In this study platelets volume and its important role as a diagnostic marker was estimated in the prevalence of type 2 diabetes mellitus (T2DM) which are associated with mean platelet volume (MPV). The aim of the study was to investigate if platelets were activated in diabetes and its associated vascular complications by measuring the MPV in the diabetics compared to the non-diabetics, and to determine the correlation of MPV with …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 47–52 Read article
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Nt-Probnp and Nitrogen Species Measurement As Useful Biomarkers for Detection of Asymptomatic Heart Failure in Patients with Type 2 Diabetes
Abstract: Insidious heart failure is associated or complicated hypertension, coronary artery disease, diabetes, chronic lung disease, atrial fibrillation, renal failure, depression, and anemia. High plasma NT-proBNP level found to be a predictive value in detecting latent left ventricular diastolic dysfunction. The aim of the study is to detect asymptomatic heart failure in outpatient type 2 diabetic patients using plasma NT-proBNP as a diagnostic biomarker of heart failure and nitrogen species as …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 1, 2015 · pp. 8–12 Read article
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Case Study: A Patient with Uncontrolled Type 2 Diabetes and Carbuncle in Thigh Whose Diabetes is Managed by Ayurvedic Intervention
Abstract: Background: Diabetes mellitus is a global pandemic with substantial public health implications. It is a well-known multifactorial metabolic condition defined by unusually high blood glucose levels caused by a shortage of insulin, either absolute or relative. Type-2 diabetes is the most common type of diabetes, accounting for 90% of all diabetics. Carbuncle is a rare skin and soft tissue infection that primarily affects uncontrolled diabetics. Presentation of the Case: A …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 3, 2021 · pp. 8–13 Read article
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A Study on Safety and Efficacy of Newer Anti-diabetic Drugs (Sitagliptin, Vildagliptin) in Type 2 Diabetes mellitus
Abstract: AbstractType 2 diabetes mellitus accounts for as much as 90% of all cases of diabetes mellitus. India leads the world with largest number of diabetes subjects earning the dubious distinction of being term the “Diabetes Capital of the world”. The present study was aimed to evaluate safe and effective management of type 2 diabetes mellitus patients by using newer anti-diabetic drugs. A total of 81 patients were interviewed; out of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 27–30 Read article
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Development of High Sugar Induced Hyperglycemia or Type 2 Diabetes in Zebrafish (Danio rerio) Model
Abstract: Type 2 diabetes (T2D) is the most common form of diabetes, accounting for about 90–95% of all diagnosed cases of diabetes in adult. It is mainly recognized by an increase in blood glucose levels, i.e., hyperglycemia. Earlier, zebrafish (Danio rerio) has been already used for the study of various metabolic diseases. In the present study, a validation study was done for the earlier developed acute hyperglycemia zebrafish model by using …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 60–66 Read article
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Effect of Nutrition Counseling on Anthropometry of Middle Aged Type 2 Diabetics
Abstract: A sample of 90 middle-aged type 2 diabetics (45 male and 45 female) was selected from the OPD of the Government Sardar Patel Medical College and Hospital, Bikaner, and were equally divided in three groups on the basis of BMI, obese, normal weight and underweight. Further, equal number of males and females were studied under each group. Purposive sampling was used to select the subjects who were suffering from type …
Published in Research and Reviews: A Journal of Health Professions · Vol. 2, Issue 2, 2012 · pp. 8–20 Read article
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Ayurveda Treatment of Type 2 Diabetes Mellitus WSR Kaphaja Prameha: A Case Study
Abstract: Type 2 diabetes mellitus is highly prevalent in society nowadays. This is result of deranged lifestyle and food habits of present era. It can be corelated with Prameha in Ayurveda, that is mentioned in all ancient texts of Ayurveda. In present case study, a 45 years old obese patient visited Kayachikitsa OPD with complains of lethargy, weakness, excess sleep, lack of sexual desire and calf pain. He was diagnosed to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 3, 2024 · pp. 1–4 Read article
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Anthropometric Measurements as Cardio-Metabolic Risk Factors Did Not Associate with Echocardiography Determinants in Type 2 Diabetes
Abstract: Obesity and Type 2 diabetes (T2D) are risk factors for cardiovascular events. Anthropometric measurements are considered as independent risk factors for these events. This study aimed to assess the link between anthropometric measurements that are considered as risk factors for cardiovascular events and echocardiography determinants in T2D. A total number of 50 T2D patients (20 males and 30 females) with a median age of 58.8 years were included in this …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 1, 2015 · pp. 1–6 Read article
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Metabotropic Receptor Based Target for Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus
Abstract: G protein coupled receptors (GPCRs) moreover called as metabotropic receptor addresses the greatest gathering of film proteins in the human genome. GPCRs share a regular essential characteristic of seven hydrophobic transmembrane (TM) sections (heptahelical structure), with an extracellular amino end and an intracellular carboxyl end their assistant and valuable closeness of GPCRs stays rather than the fundamental OK assortment of the ordinary GPCR ligands. GPCRs keep on being critical revelation …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 17–27 Read article