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90 articles for “Stability-indicating method”
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article
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Reliability-Based Prediction of Bearing Capacity of Shallow Foundation Along Ajaokuta-Kaduna-Kano Pipeline Track
Abstract: This paper investigates the geotechnical properties and reliability-based bearing capacity predictions for shallow foundations along the proposed Ajaokuta-Kaduna-Kano (A-K-K) pipeline track in Nigeria. The variability of subsoil properties along this route poses significant challenges to ensuring foundation stability and safety, necessitating an in-depth study. A total of twenty boreholes were strategically drilled at key locations to a maximum depth of 30 meters, providing comprehensive subsurface profiles. Soil samples collected from …
Published in Journal of Geotechnical Engineering · Vol. 12, Issue 1, 2025 · pp. 9–17 Read article
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A Comparative Study of Oven, Spouted Bed, and Convective Tunnel Drying Methods of Mango for Oil Production
Abstract: Mango seeds, with a high moisture content exceeding 70% (wet basis) require effective drying methods to ensure their preservation and to enhance the quality of derivative products like mango seed oil. Proper drying is essential to inhibit enzymatic activity and microbial growth, which extends the shelf life of these seeds. This study investigates multiple drying techniques, including conventional oven drying, spouted bed drying, and convective tunnel drying, to determine their …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 1, 2025 · pp. 15–19 Read article
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Dynamic Analysis of Structures Considering Waffle Slab with and without Drops and Beams
Abstract: The seismic performance of a structure is a fundamental and vital aspect of structural engineering, carrying significant importance in ensuring safety and stability. This study investigates the dynamic behavior of structures employing waffle slab designs with and without drops and beams, focusing on varying panel sizes. Commercial buildings, each comprising 12 stories with heights of 3.5 meters, were analyzed using the Response Spectrum Method in seismic Zone III, utilizing ETABS …
Published in Recent Trends in Civil Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 41–60 Read article
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Determination of Compatibility of Polymer Systems and Study of Chemical Properties of their Mixtures
Abstract: We have obtained mechanical strength of materials as a result not by synthesizing new polymers, but by using industrial polymers. We have developed a technology for obtaining new composite materials based on industrial multi-tonnage polymers of high-strength polyethylene (HSPE), polyvinyl chloride (PVC), polyurethane thermoplastic elastomer (DUTEP), butyl rubber (BR), chlorocarboxylate polyethylene (CCPE), ethylene propylene rubber (EPR). To obtain a composition from these polymers, their mixture compatibility was first determined using …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 17–29 Read article
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Modelling -Based Evaluation of Hybrid Natural Synthetic Fiber Polymer Composites for Sustainable Energy Applications
Abstract: The growing need of lightweight, high-performance, and green energy system materials has increased the research on hybrid polymer composites. This paper gives a modelling-based evaluation of polymer matrix composites which are reinforced using natural fibers like jute, sisal, bamboo in a combination with synthetic glass fibers to be used in sustainable energy sources. An analytical model has been used to assess the effect of hybrid fiber composition on mechanical, thermal, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 682–688 Read article
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Extraction, Stability, and Application of Natural Dye from Spathodea campanulata Flower: A Study on Shelf Life, Yield, and Fabric Dyeing Potential
Abstract: The growing demand for sustainable and eco-friendly alternatives to synthetic dyes has led to increased interest in natural dye sources. Spathodea campanulata, commonly known as the African Tulip Tree, is a potential source of natural dye due to its vibrant floral pigments. This study focuses on the extraction, yield, stability, and application of the dye obtained from Spathodea campanulata flowers. The dye was extracted using an aqueous method, and its …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 3, 2025 · pp. 8–15 Read article
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Influence of Static Sequences on the Thermal Behavior of Eco-Friendly Pineapple/Ramie Composites
Abstract: The increasing demand for sustainable and environmentally responsible materials has driven the exploration of natural fiber-reinforced polymer composites as potential alternatives to conventional synthetic materials. Among various natural fibers, pineapple leaf fiber (PALF) and ramie fiber are notable for their complementary characteristics—PALF offers excellent insulating behavior and lightweight structure, while ramie provides high thermal stability and strength. In the field of Eco-friendly composite product manufacturing, the processing temperature holds significant …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 732–742 Read article
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Combustion Synthesis and Comprehensive Characterization of Pure and Ni-Doped CuFe₂O₄ Nanoparticles for Functional Composite Applications
Abstract: The CuFe2-xNixO4 (x = 0, 0.1, 0.3, and 0.5) nanoparticles were synthesized using a combustion method and comprehensively characterized to understand their suitability for polymer-based composite applications. X-ray diffraction confirmed the formation of a single-phase spinel ferrite structure with crystallite sizes of 20–30 nm. Energy-dispersive X-ray spectroscopy verified the successful incorporation of Ni ions into the CuFe₂O₄ lattice, while FE-SEM analysis revealed uniformly dispersed nanoscale particles desirable for composite reinforcement. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1–11 Read article
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Development and Evaluation of a Cost-Effective UV-Protective Cream Containing Para-Aminobenzoic Acid and Aloe Vera for Indian Climatic Conditions.
Abstract: The increasing incidence of ultraviolet (UV) radiation-induced skin disorders has heightened the demand for effective, affordable photoprotective agents, especially in countries with high sun exposure such as India. This study aimed to develop a cost-effective and efficient UV-B protective cream formulation suitable for populations in Indian latitudes. Para-aminobenzoic acid (PABA) was selected as the primary sunscreening agent due to its high UV-B absorption efficiency, low toxicity, and affordability compared with …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 7–18 Read article
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Panfacial Trauma- A Case Report
Abstract: The majority of panfacial fractures are accompanied by concurrent organ damage. Panfacial fracture management is difficult and necessitates careful planning, sequencing, and sufficient understanding of the anatomy and management of the condition. In any trauma situation, the ABCDEs (airway, breathing, circulation, disability, and exposure) always remain the primary care priorities. Maxillofacial surgeons are essential in the early stabilization of fractures, the management of localized bleeding into the face, and the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 21–25 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Enhance Thermal and Conductive Properties through Graph Neural Network-Based Machine Learning-Driven Advanced Polymer Material Design
Abstract: Advanced polymer materials are widely used in modern engineering and manufacturing because of their lightweight nature, flexibility, durability, and adaptability to different applications. However, designing polymer materials with enhanced thermal and electrical properties remains a challenging task. The performance of polymers is influenced by a complex combination of molecular structures, filler materials, processing parameters, and nanoscale interactions. Conventional optimization methods often require extensive experimental trials and computational resources, making it …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Thermal and Microstructural Evaluation of Natural-Glass Fiber Hybrid Composites: Sustainable Alternatives to Synthetic Materials
Abstract: The scope of engineering requirements for composite materials, which mix features from several elements engaged in engineering applications to enable greater performance, cannot be adequately understood in this way. The most recent of these materials are hybrid composites, which combine synthetic and natural fibers, particularly glass fibers, and are anticipated to create new, promising materials in terms of their ties to cost, performance, and consistency. From the perspective of their …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1275–1285 Read article
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Heavy Metal Removal from Textile Industrial Effluent using Banana Exocarp Derived Cellulose Acetate Graphene Nanocomposite Membranes
Abstract: The disposal of textile effluent is responsible for serious human health concerns and above all environmental concerns to all kind of species. This indicates that there is immediate and urgent need of emerging, efficient with sustainable recycling technologies. In this paper, banana exocarp as agriculture-based waste, in terms of substrate was utilised as major raw material. The extracted cellulose from the substrate with homogeneous acetylation process, transformed into cellulose acetate …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 51–62 Read article
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Improving Black Cotton Soil with Sodium Hydroxide and Fly Ash: An Assessment of Optimum Moisture Content, Dry Density, and California Bearing Ratio
Abstract: This study investigates the stabilization of Black Cotton Soil (BCS), an expansive clayey soil primarily composed of montmorillonite minerals, using sodium hydroxide (NaOH) and fly ash. Due to its high plasticity and significant volume changes with moisture, BCS is challenging for construction purposes. Adding NaOH and fly ash can potentially improve the soil's moisture tolerance, compressibility, and reduce its plasticity, making it more suitable for structural applications. The research evaluates …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 192–201 Read article