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16 articles for “QS systems”
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Antivirulence Therapy- A Promising Alternative Technique for Antibiotic Resistance
Abstract: Antibiotic resistance is increasing at an alarming rate. Over the years there has been a steep rise in number of antibiotic resistant bacteria. This in turn has led to a dip in overall efficacy of a wide range of antibiotics. The last new class of antibiotics was introduced in 2003, but after that there has not been any significant discovery in this area. To overcome this problem of antibiotic resistance …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 3, 2020 · pp. 1–14 Read article
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Determination of Quick Switching Double Sampling System by Attributes under Fuzzy Poisson Distribution: Acceptance Number Tightening
Abstract: AbstractAcceptance sampling plans are used to accept or reject the lots based on the inspection of samples. A mixture of acceptance sampling plans with switching rules for changing from one plan to another are called acceptance sampling schemes. The simple and most generally used sampling scheme is quick switching system (QSS-1). Quick switching system with reference to single sampling plan is a system which requires fewer samples for processes running …
Published in Current Trends in Information Technology · Vol. 7, Issue 3, 2017 · pp. 17–23 Read article
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INVESTIGATING PHYTOCHEMICAL INHIBITORS OF PSEUDOMONAS AERUGINOSA'S AHL SYNTHASE LASI: A PATH TOWARD NOVEL THERAPEUTIC AGENTS
Abstract: Objectives: This study intended to explore the potential of phytochemicals from Allium sativum to inhibit AHL synthase LasI, a critical protein of the Quorum Sensing (QS) pathway in Pseudomonas aeruginosa, with the ultimate objective of developing therapeutic agents for managing P. aeruginosa infections. Methods: The physicochemical properties, toxicity, aggregation ability and binding potential of phytochemicals from Allium sativum to the protein AHL synthase LasI were determined. Physicochemical properties, toxicity and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 40–54 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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Quantification of Snow/Glacier Melt Impacts of Historical and Future Climate Change on Eastern Himalayan River
Abstract: Millions of the population on Eastern Himalayan Rivers (EHR) totally depend on, domestic use, agriculture, and hydropower. Several studies found that climate warming threatens this EHR's hydrological regime. In order to understand the hydrologic response of their headwaters and how climate change affects streamflow, a hydrological modeling study is conducted in the Teesta River Basin (TRB) in EHR using an open-source Quantum Geographical Information System (QGIS) with semi-distributed QSWAT1.5 (Soil …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 508–524 Read article
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A Review: Quantitative Structure Activity Relationship
Abstract: AbstractDrug discovery is a risky, costly and time-consuming process depending on multidisciplinary methods to create safe and effective medicines. Although considerable progress has been made by high-throughput screening methods in drug design, the cost of developing contemporary approved drugs did not match that in the past decade. The major reason is the late-stage clinical failures in Phases II and III because of the complicated interactions between drug-specific, human body and …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 3, 2016 · pp. 20–24 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Routing Protocols in FANETs with Future Enhancements
Abstract: Flying Ad Hoc Networks (FANETs), which are swarms of Unmanned Aerial Vehicles (UAVs), are an emerging solution which revolutionized the area of mission-critical and infrastructure-less communication systems. These networks provide real-time data transfer for use cases such as disaster relief, battlefield observation, environmental monitoring, and 6G-based smart cities. However, the dynamic profile of FANETs, which is defined by high 3D mobility, limited energy resources, unstable wireless links, and constant topology …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 8–13 Read article
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An Investigative Study of Quantum-safe Secure Multi-party Computation
Abstract: This article represents the comprehensive investigation in the emerging field of quantum-safe secure multi-party computation (QSSMPC) and presents novel perspectives to address the impending threat posed by quantum computers to classical cryptographic systems. As the era of quantum computing approaches, traditional encryption methods become vulnerable to quantum algorithms, necessitating the development of quantum-resistant cryptographic protocols. In this context, the paper introduces innovative approaches to secure multi-party computation in a quantum-safe …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 1, 2024 · pp. 39–44 Read article
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Harnessing Artificial Intelligence for Precision Physics: A Machine Learning Framework for Data Reconstruction in Support of India's Deep-Tech Missions
Abstract: India's emergence as a global leader in deep-tech innovation is driven by ambitious scientific megaprojects, including the Laser Interferometer Gravitational-Wave Observatory (LIGO)-India, the X-ray Polarimeter Satellite (XPoSat), the Aditya-L1 solar observatory, and the National Quantum Mission (NQM). However, the unprecedented scale and complexity of the observational data generated by these missions present severe computational bottlenecks. Traditional analytical frameworks struggle with non-stationary noise transients, diffusion blurring, and the exponential scaling limits …
Published in Research & Reviews : Journal of Physics · Vol. 15, Issue 2, 2026 · pp. 48–55 Read article
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Experimental Studies and in silico Analysis on Quarum Sensing and System Simulation in Pseudomonas aeruginosa
Abstract: Pseudomonas aeruginosa is the most common pathogenic bacterium present in human microbial flora, biofilms, soil and water associated and support self microbial communications and survilance. The present study shows estimated protein concentration present in two days grown in Mullar hinton broth was resulted around 32.5 mg/ml. The studies in protein interaction on X-ray film with aqueous fruit and vegetable extracts showed good results with apple, straw berry, cucumber, grape, orrange, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 1, 2018 · pp. 1–8 Read article
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Inhibition of Quorum Sensing to Mitigate the Risks of Membrane Biofouling in Biological Wastewater Treatment
Abstract: Membrane-based systems play a pivotal role in various applications, providing efficient separation, purification, and filtration processes across diverse industries such as water purification and desalination. However, this system faces major challenge of membrane biofouling impacting the efficiency and sustainability of such systems. Biofouling occurs when various microorganisms like bacteria, fungi, etc. adheres to the surface of membrane and form biofilm which results in reducing membrane permeability and increasing its operational …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 1, 2024 · pp. 18–26 Read article
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Performance Analysis of Space Shift Keying and Quadrature Space Shift Keying for MIMO Channels
Abstract: In wireless communication the propagation channel is characterized by multipath propagation due to scattering on different obstacles. MIMO takes advantage of multi-path and uses multiple antennas to send multiple parallel signals from transmitter. “Multi-path” occurs when different signals arrive at the receiver at various times. MIMO exploits the space dimension to improve wireless systems capacity, range and reliability. There are two different modulation techniques that exploits the best features of …
Published in Research & Reviews : Journal of Space Science & Technology · pp. 46–55 Read article
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Toxicology 4.0: Integrating Artificial Intelligence, Big Data, Health Informatics, and Precision Analytics for Predictive Toxicity Assessment, Real-Time Toxicovigilance, and Personalized Patient Safety
Abstract: Background: Toxicology is undergoing a major transformation, increasingly described as Toxicology 4.0, driven by the integration of artificial intelligence (AI), big data analytics, health informatics, and precision analytics. Conventional toxicity testing is limited by high costs, lengthy timelines, and challenges in translating animal and low-throughput in vitro findings to humans. Aim and Objectives: To comprehensively evaluate the emerging role of Toxicology 4.0 in predictive toxicity assessment, real-time toxicovigilance, and personalized …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article