Search
53 articles for “Pulmonary Diseases.”
-
Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
-
Influence of Geographic Disparity on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients from Two Cities of Northern India
Abstract: Objectives: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease associated with a notable amount of morbidity and mortality and characterized by progressive airflow obstruction. A decline in lung function, which is a hallmark of COPD, can be measured using spirometry. Yet with conflicting results, a link is found between geographical altitude and prevalence of COPD. Therefore, the main aim of this study was to assess the effect …
Published in Research and Reviews: A Journal of Health Professions · Vol. 10, Issue 1, 2020 · pp. 29–36 Read article
-
Pharmacological and Nonpharmacological Management of Chronic Obstructive Pulmonary Disease (COPD): An Overview
Abstract: Chronic obstructive pulmonary disease (COPD) is a composite state with many characteristics that are agreeable to treatment. A well sympathetic of the physiology of COPD and better tackles to assess consequences have led to advances in our capability to cure this disease. Pharmacological methods can progress patients’ eminence of life significantly by dipping dyspnea and limiting exacerbations. Although, none of the drugs currently obtainable for COPD are able to deduce …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 45–69 Read article
-
Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
-
From Clinic Formulation to Development of Acebrophylline
Abstract: Acebrophylline, a commonly utilized bronchodilator with anti-inflammatory properties, has become a key therapeutic option for managing respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis. This review explores the journey of Acebrophylline from its clinic formulation to its development and commercialization, focusing on the key aspects of formulation strategies, pharmacological properties, and regulatory considerations. The drug’s dual mechanism of action, which involves both bronchodilation and anti-inflammatory effects, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
-
Comprehensive Care in COPD: Integrating Non-Pharmacological Treatments in COPD
Abstract: The substantial worldwide respiratory disorder known as chronic obstructive pulmonary disease (COPD) calls for multifaceted care approaches in addition to medicines. The incorporation of alternatives to drugs into chronic pulmonary disease care is the main topic of this article, as it plays a crucial role in enhancing the lives of patients. Pulmonary rehabilitation, exercise training, nutritional support, psychological support, oxygen therapy, and surgical or interventional procedures are some of the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 12–18 Read article
-
Effects of Expiratory Resistance Training using Spirometer in Improving Pulmonary Functions among Chronic Bronchitis Patients
Abstract: Achieving and maintaining health is an ongoing process, shaped by both the evolution of health care knowledge and practices as well as personal strategies and organized interventions for staying healthy. Public health has been described as "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals." It is concerned with threats to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 2, Issue 2, 2013 · pp. 14–20 Read article
-
In Silico Screening and Molecular Docking of Cynodon dactylon phytochemicals against COPD-Associated Proteins
Abstract: Chronic Obstructive Pulmonary Disease or COPD is a pulmonary disease that obstructs airways and alveoli accompanied by respiratory issues like emphysema and bronchitis. This disease is caused mainly by inflammatory responses of the body to foreign particles that enter the respiratory path including tobacco smoke, air pollutants and irritants. The hallmark of COPD is excessive inflammation caused by imbalance in protease anti-protease activity. Proteases like elastase breakdown the ECM of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
-
Flavonoids Attenuate Airway Mucin Expression, Production and Secretion Induced by Various Inducers
Abstract: Muco-obstructive respiratory disease is caused by changing normal biophysical properties of mucus including alteration of mucin concentration, ion composition and airway surface hydration. Flavonoids are one type of polyphenols which regulate mucin gene expression and consequently inhibit mucus secretion. Thus, this review aimed to discuss the effects of different flavonoids on regulation of various airways mucin gene expression and inhibition of the production of a major airway mucin core protein …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 2, 2019 · pp. 1–13 Read article
-
A Research Study and Report on the Role of Clinical Pharmacy Services on the Management of Chronic Respiratory Disorder Asthma to an ESI Hospital
Abstract: Chronic respiratory disorder (CRDs) are disease of the airways and other structure of the lung. A number of the foremost common are asthma, chronic obstructive pulmonary disease (COPD), occupational lung diseases and pulmonary hypertension. Additionally, to tobacco smoke, other risk factors including air pollution, occupational chemicals and dusts, and frequent lower respiratory infections during childhood. CRDs aren’t curable, however kinds of treatment that help dilate major air passages and improve …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 13–24 Read article
-
Classification of Pattern using Spline Function and Statistical Data Mining: Review Paper
Abstract: ABSTRACTMany people are affected by lung diseases. Respiratory diseases are curable in early detection. Spirometry is valuable for diagnosing specific lung disorders as well as detecting lung disease at an early stage. Spirometry is most widely used pulmonary function test that is essential to measure the volume of air exhaled from the fully inflated lung as a function of time. The output of spirometry is inthe form of graphs i.e., …
Published in Journal of Computer Technology & Applications · Vol. 3, Issue 1, 2012 · pp. 37–42 Read article
-
Preventive Dentistry at All Levels of Health Care Services: A Call for Oral Health Care Reform
Abstract: As today’s life expectancy seems to be increased both in developing and developed nations. The major contributor of this success can be of various public health interventions undertaken across the globe. At the same time this achievement brings along many challenges that the health care system, which includes various public health services and public programs should be prepared to face. These challenges include growing burden of chronic illnesses, the rising …
Published in Research and Reviews: A Journal of Dentistry · Vol. 6, Issue 3, 2015 · pp. 36–40 Read article
-
Dasatinib Induced Pulmonary Hypertension
Abstract: Dasatinib (Das) is a second-generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML) in patients who are resistant or intolerant to imatinib, as well as in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) patients. Dasatinib-induced pulmonary arterial hypertension (PAH) is a known but rare adverse effect of dasatinib and is grouped under Group-1 PAH. The mechanism of PAH development is not fully known, but …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 92–95 Read article
-
Wearable Device to Keep Track of Respiratory Tract Diseases for Future Diagnosis Using History
Abstract: We are living in a generation in which the humans are exposed to an unhealthy environment and with unhealthy habits, resulting in respiratory issues. In most of the cases, it causes fatal diseases like Chronic Obstructive pulmonary disease (COPD) have no initial symptoms, when the disease is at its serious stage the symptoms can be realized due to this character proper treatments cannot be given to the victim at the …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 8, Issue 2, 2021 · pp. 51–58 Read article
-
Prevalence of Risk-Factors of Non-Communicable Diseases among Rural Adults
Abstract: Non-communicable diseases are the leading cause of death in the world, as well as in India. India is facing a growing burden of non-communicable diseases. NCDs accounts for 53% of deaths in India in 2008. The four main types of non-communicable diseases are cardiovascular diseases (like heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructed pulmonary disease and asthma) and diabetes. The important risk factors identified for …
Published in Journal of Nursing Science & Practice · Vol. 6, Issue 1, 2016 · pp. 43–48 Read article
-
A Narrative Review on Tuberculosis Disease Transmission, Treatment, Prevention, Emergency Care, and Vaccine Allocation in Second Highest Populated Country (India)
Abstract: Tuberculosis, an airborne illness caused by Mycobacterium tuberculosis, is a highly contagious disease primarily impacting the lungs, though it can also affect other body parts, excluding hair and nails. There are two main types of tuberculosis: pulmonary tuberculosis (PTB), which targets the lungs, and extrapulmonary tuberculosis (EPTB), which involves other areas such as lymph nodes, bones, joints, and the nervous system. The theme for World Tuberculosis Day in 2024 is …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article
-
Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article
-
Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
-
AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
-
Shadows of Uncertainty: When Pneumonia Isn’t Pneumonia
Abstract: Pneumonia is a common medical condition encountered in hospitalized patients and remains a cause of morbidity worldwide. Identifying and initiating appropriate treatment in febrile patients who present with respiratory symptoms and radiographic infiltrates, reduce hospital stay, minimize complications, and lower healthcare costs. However, the assumption that every pulmonary infiltrate or opacity seen on a radiological imaging represents an infectious process such as pneumonia can lead to misdiagnosis, unnecessary investigations, prolonged …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 24–29 Read article