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24 articles for “Plaque”
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Nanorobots: The Fight against Cholesterol
Abstract: Cardiovascular disease (CVD) rests leading reason of death globally, with atherosclerosis, the buildup of plaque in arteries, playing a central role. Current treatment strategies, including lifestyle changes and medications, often fall short in completely reversing or preventing the progression of atherosclerosis. This has spurred the exploration of innovative approaches, with nanorobotics emerging as a promising avenue for targeted plaque control and high-density lipoprotein (HDL) enhancement. This article discusses how nanorobots …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 23–32 Read article
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Review of Atorvastatin As A Potent Drug For Cardio-Vascular Disease(CVD)
Abstract: Cardiovascular disease (CVD), particularly atherosclerosis, remains the leading cause of death worldwide, significantly burdening public health, especially in Western societies. Metabolic syndrome and arrhythmic complications further exacerbate cardiovascular morbidity and mortality. Among restorative specialists, statins particularly atorvastatin have gotten to central in both the essential and auxiliary anticipation of coronary heart infection (CHD) due to their strong lipid-lowering properties and additional pleiotropic impacts. Atorvastatin, a selective HMG-CoA reductase inhibitor, not …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 8–18 Read article
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Banyan Aerial Root Bristle Toothbrush with Oral Irrigator
Abstract: In this project we tried to accomplish Neem bristles which are economically feasible tooth brush that keeps your teeth away from microorganisms. The Neem brush consists of a plastic handle and neem seedling bristles attached to the head of the brush. Toothbrush occupies a prominent and very important place among the dentifrice available today. In this century, most people take care of their health that includes the oral hygiene. They …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 2, 2023 · pp. 18–23 Read article
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A Case Study on Ayurvedic Management of Psoriasis.
Abstract: Psoriasis is non-contagious, chronic autoimmune disease which causes inflammation and hyper-proliferation of the skin. It is characterized by erythematous plaques that are clearly defined and associated with severe itching and silvery scaling, especially on extensor surfaces, scalp and nails. At times, it may manifest as localized or generalised pustular eruption which usually follows relapses and remissions pattern. Psoriasis may lead to other autoimmune diseases like psoriatic arthritis. In Ayurveda, Variety …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 18–22 Read article
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Revealing the Hemodynamic Orchestra: Contrasting Analysis of Blood Flow Patterns in a Bifurcated Carotid Artery
Abstract: Understanding blood flow patterns in the carotid artery (CA) is crucial for detecting cardiovascular diseases. Computational fluid dynamics simulations compared non-Newtonian (non-Newt) and Newtonian (Newt) models under pulsatile and laminar flow. CA geometry was accurately designed using ANSYS Space Claim & Fusion360, and simulations were run in ANSYS Fluent. Discrepancies between non-Newt and Newt models were found, especially in bifurcation's distal regions prone to plaque. Pressure ranged from 27.870 Pa …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 229–247 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Psoriasis: Latest Trends in Treatment, Diagnosis and Management in Medical Science
Abstract: Psoriasis is a common chronic inflammatory and autoimmune skin disease that primarily affects the skin. It affects about 2–4% of the world populations. It is clinically characterized by skin rashes, highly inflamed red scale itchy plaque. Abundant therapeutic agents are accessible for the treatment of psoriasis. Wide range of therapeutic mediators such as coal tar, topical corticosteroids, anthralin, retinoid, calcineurin inhibitors, methotrexate, cyclosporine are proven to be effective in treating …
Published in Research and Reviews : A Journal of Biotechnology Read article
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Infective Endocarditis, Result of Chronic Periodontal Disease: A Real and Present Danger
Abstract: Introduction: Endocarditis is an inflammation of the endocardium, the inner lining of the heart and heart valves. It is usually caused by bacteria and is associated with high mortality and morbidity. It can result from transient bacteremia from the oral cavity. Streptococci are the primary colonizers of tooth surface and are instrumental in development of the complex oral biofilm, dental plaque. Streptococcus sanguinis is one of the abundant oral commensals …
Published in Research and Reviews: A Journal of Dentistry Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Concern for Public Health: Periodontitis
Abstract: Periodontitis, a severe form of gum disease, erodes the bone that supports teeth and results in tooth loss. It is caused by bacterial infection and inflammation of the soft tissues around the teeth. About 70% of people 65 years of age and older are affected, on average. Red, bleeding, sensitive gums, foul breath, and receding gums are hallmark indications. Depending on the severity, a full dental examination, the insertion of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 22–26 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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A Novel Solution to Oral Hygiene
Abstract: This paper proposes a novel approach to oral health monitoring through the development of a smart toothbrush equipped with a camera, pH sensor, and temperature sensor. The integration of these sensors allows for real-time monitoring and early detection of potential oral health issues such as cavities, gum disease, pyorrhea and enamel erosion. The camera provides visual data for assessing plaque buildup and other visible signs of oral health problems, while …
Published in Journal of Microwave Engineering and Technologies · Vol. 11, Issue 2, 2024 · pp. 29–34 Read article
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Clinical Experiences of Vaman Karma Without Vamak Yoga In Psoriatic Arthritis- A Case Study
Abstract: The classical texts explain various methods of conducting Vaman Karma procedures which is also associated with the description of various medications and their formulations for such procedures. However, as observed in some cases it is crucial to induce Vaman karma without Vamak yoga. The aim of this paper is to discuss this case by combining classical reasoning along with clinical experiences through a case study of Psoriatic arthritis complicated with …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 3, 2024 · pp. 13–18 Read article
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In Silico Analysis and Docking Study of the Active Phytocompounds of Bacopa monnieri Against Alzheimer Disease
Abstract: Objective: Alzheimer’s is a neurodegenerative disease and is the cause of 60–70% of cases of dementia. It infected a million people worldwide. An effort was undertaken to explore the potential of natural compounds found in Bacopa monnieri, a plant renowned for its extensive medicinal properties in Indian Ayurveda, to combat the disease. This was achieved through molecular docking studies, evaluation of drug-likeness, and comprehensive ADME (absorption, distribution, metabolism, and excretion) …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 1–13 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Clinical Evaluation of Ayurvedic Intervention (Mahamanjishathadi Kwatha, Kaishora Guggulu, Panchatikta Ghrita, Eranda Taila) in the Management of Ekakushtha W.S.R. to Psoriasis
Abstract: Introduction: Psoriasis is a chronic skin condition causing scaly plaques, typically on extensor surfaces, scalp, and nails, and often leads to quality of life impairments, including physical and mental health challenges. Ayurveda offers a holistic approach targeting root causes and balancing body and mind, while conventional treatments focus on symptom management through therapies that may cause side effects and recurrence. Aim and Objectives: The study aimed to assess the efficacy …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 Read article
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Assessing the Impact of Chlorhexidine Mouthwash on Radiation-Induced Oral Mucositis in Head and Neck Cancer Patients: A Pre-Experimental Study
Abstract: Introduction: Cancer poses a major global health threat and is the second leading cause of death worldwide, following cardiovascular diseases, particularly in developed countries. Among cancers, head and neck cancer ranks as the 6th most common, representing about 6% of all cancer diagnoses. One of the frequent side effects of radiotherapy (RT) is mucositis, an inflammation of the mucous membranes. Chlorhexidine, a commonly used antiseptic and disinfectant found in mouthwashes, …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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Erythrodermic Psoriasis: A Case Report Highlighting Clinical Features and Management
Abstract: Background: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis that presents as widespread erythema, scaling, and systemic complications such as fever, dehydration, and electrolyte imbalances. It requires urgent medical attention due to the risk of life-threatening complications, including sepsis and multi-organ failure. The condition can arise de novo or as an exacerbation of pre-existing psoriasis, often triggered by medication withdrawal, infections, or systemic inflammation. Case Presentation: We …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 01–05 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article