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45 articles for “Lab-on-a-chip”
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Experimental Studies to Record the Lithographically Fabricated Microstructures by Surface Profilometry and Scanning Electron Microscopy for Microfluidic Laboratory-on-a-Chip Systems
Abstract: In this research paper, the poly(methyl methacrylate) (PMMA) microfluidic laboratory-on-a-chip system is fabricated in the cleanroom laboratory by maskless lithography, hot embossing lithography and direct bonding technique. The microstructures of the lab-on-a-chip system are measured by surface stylus profilometer. Also, the images of microstructures of lab-on-a-chip system are captured by using scanning electron microscopy (SEM). This fabricated lab-on-a-chip system is useful in bioengineering applications.
Published in Journal of Polymer & Composites · Vol. 4, Issue 1, 2016 · pp. 27–36 Read article
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How Microfluidics Are Used in Modern Science: Lab-on-A-Chip
Abstract: Microfluidics has changed modern research by making lab-on-a-chip (LOC) technologies that combine multiple lab functions into small, portable devices. These little platforms make it easier to correctly handle small amounts of fluid, which saves time, money, reagents, and automation. This article talks about microfluidics and how it helps LOC technology go forward in all areas of science. We look at important uses of biomedical diagnostics, drug development, environmental monitoring, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 35–48 Read article
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Short Report to Describe the Surface-driven Microfluidic Flow in Fluid Mechanics
Abstract: In this short report, a brief review on surface-driven microfluidic flow is provided. Also, the maskless lithography and indirect bonding technique are used to fabricate a single SU-8 based glass microfluidic device. Dyed ethylene glycol is prepared as working liquid to test the fabricated device. The surface-driven microfluidic flow of dyed ethylene glycol is recorded by a CMOS camera catching 25 frames per second with a corresponding time-scale resolution of …
Published in Recent Trends in Fluid Mechanics Read article
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Short Experimental Report on Lithographic Technique in Microfluidics
Abstract: In this experimental work, a single SU-8 based glass microfluidic device is fabricated by the maskless lithography and indirect bonding technique. The sealing by indirect bonding technique is perform during the hard baking in maskless lithography. Dyed ethylene glycol is prepared as the working liquid. A CMOS camera catching 25 frames per second with a corresponding time-scale resolution of 0.04 second is used to record the surface-driven microfluidic flow of …
Published in Journal of Microwave Engineering and Technologies · Vol. 8, Issue 3, 2021 · pp. 1–5 Read article
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Surface-Driven Microfluidic Flow in Fluid Mechanics
Abstract: In this short report, a brief review on surface-driven microfluidic flow is provided. Also, the maskless lithography and indirect bonding technique are used to fabricate a single SU-8 based glass microfluidic device. Dyed ethylene glycol is prepared as working liquid to test the fabricated device. The surface-driven microfluidic flow of dyed ethylene glycol is recorded by a CMOS camera catching 25 frames per second with a corresponding time-scale resolution of …
Published in Recent Trends in Fluid Mechanics · Vol. 8, Issue 3, 2021 · pp. 1–5 Read article
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Next Generation Immunoassays for Infectious Diseases of Animals
Abstract: Veterinary diagnostics has an essential role to play in the management and control of infectious diseases. Immunodiagnostics originated towards the end of 19th century with the advent of agglutination- and precipitation-based serological techniques. Progress in immunodiagnostics during the 20th century is marked by development of complement fixation test, and later, fluoro-, radio- and enzyme-immunoassays during 1950s, 1960s and 1970s, respectively. Various immunodiagnostic test formats were improved for their performance characteristics …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 22–43 Read article
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Surface-Driven Capillary Flow of AqueousIsopropyl Alcohol in the Sudden Expansion PMMA Microchannels
Abstract: Author has fabricated the PMMA sudden expansion microchannels by the maskless lithography, hot embossing lithography, drilling, direct bonding and chip separation technique. The effect of channel aspect ratio on the surface-driven capillary flow is studied in the sudden expansion microchannels fabricated by PMMA as a polymeric material. Also, the effect of surface wettability on the surface-driven capillary flow is studied in the sudden expansion microchannels fabricated by PMMA. This study …
Published in Emerging Trends in Chemical Engineering · Vol. 4, Issue 2, 2017 · pp. 1–4 Read article
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Passive Capillary Flow of Aqueous Microparticle Suspensions in the Sudden Expansion PMMA Microchannels
Abstract: AbstractAuthor has fabricated a set of sudden expansions micro channels in the polymethylmethacrylate (PMMA) microfluidic devices by the maskless lithography, hot embossing lithography, drilling, air dielectric barrier discharge (DBD) plasma processing, direct bonding technique and chip separation technique. The surface-driven capillary flow of dyed water and three individual aqueous microparticle suspensions are studied with respect to the effects of channel aspect ratio, effective viscosity and surface wettability. The number densities …
Published in Trends in Opto-electro & Optical Communication · Vol. 7, Issue 1, 2017 · pp. 13–17 Read article
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Short Review on the Flow and Filtration of Polystyrene Microparticles in Micron-Scale Fluid Mechanics towards the Applications related to fluidic Microelectromechanical Systems
Abstract: Maskless lithography, hot embossing lithography and direct bonding technique are useful to fabricate the polymethylmethacrylate (PMMA) microfluidic devices. Also, maskless lithography and indirect bonding technique are useful to fabricate the SU-8 based glass microfluidic devices. In this work, a short review on microfluidic flow and microfluidic filtration of microparticles is provided by author related to the micron-scale fluid mechanics. This review may be useful to perform the blood filtration in …
Published in Journal of Microelectronics and Solid State Devices Read article
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Manufacturing Processes and 3D Printing of Health Diagnostic Tools: Economic Analysis of Open Source Frameworks
Abstract: Health diagnosis tools, for example, the incorporation of 3D printing into their manufacturing, drastically changed medical technology, providing cheap, customizable, fast tools in the field. This transformation has been accelerated by open-source frameworks that decrease dependence upon proprietary manufacturing and increase accessibility to diagnostic tools. Economic benefits of open-source 3D printing include reduced production costs, less dependence on global supply chains, and better equity of access to health care globally. …
Published in Journal of Open Source Developments · Vol. 12, Issue 1, 2025 · pp. 43–46 Read article
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Advances in Analytical Chemistry Research Methodology: Trends and Applications
Abstract: Analytical chemistry is critical to scientific study because it allows for the accurate identification, measurement, and characterization of chemical compounds. Recent advances in methodology have improved accuracy, sensitivity, and efficiency, with techniques such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Mass Spectrometry (MS), and Nuclear Magnetic Resonance (NMR) spectroscopy transforming analytical procedures. The combination of Artificial Intelligence (AI) and Machine Learning (ML) has enhanced data processing, pattern recognition, and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 2, 2025 · pp. 10–18 Read article
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Experimental Studies on the Capillary Flow Phenomena in Polyimide Based Glass Microfluidic Devices
Abstract: The polyimide based glass microfluidic devices are fabricated using the maskless lithography. Water is the only working liquid in this work. The effects of micropillar side length, microfluidic friction and surface area to volume ratio on the surface-driven capillary flow of water are studied experimentally. The surface-driven capillary flow of water is slower due to higher microfluidic friction. This work will be useful to control the water inside the microfluidic …
Published in Emerging Trends in Chemical Engineering · Vol. 4, Issue 3, 2017 · pp. 22–26 Read article
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Recording of Leakage-free Surface-Driven Capillary Flow of Dyed Water in the Dual Sudden Contraction Microchannels
Abstract: Dual sudden contractionpolymethylmethacrylate (PMMA) microchannels are fabricated by the maskless lithography, hot embossing lithography, direct bonding technique, and atmospheric pressure air dielectric barrier discharge (DBD) plasma processing. The surface-driven capillary flow of dyed water is faster on the processed PMMA surface than the pristine PMMA surface. The surface-driven capillary flow of dyed water is slower in the wider portion and faster in the narrower portion of any dual sudden contraction …
Published in Emerging Trends in Chemical Engineering · Vol. 4, Issue 2, 2017 · pp. 40–44 Read article
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Passive Capillary Flow of Aqueous Working Liquids in the PMMA Microchannel Bends
Abstract: In this work, passive capillary flows or surface-driven capillary flows are recorded in polymethylmethacrylate (PMMA) microfluidic devices using aqueous ethanol and aqueous isopropyl alcohol (IPA) as chosen aqueous working liquids. Microchannel bends are the chosen microfluidic devices with the selected microchannel widths of 50, 120 and 200 micron. This work will be useful to fabricate the PMMA laboratory-on-a-chip systems for bioengineering applications.
Published in Journal of Catalyst & Catalysis · Vol. 5, Issue 1, 2018 · pp. 21–24 Read article
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Effect of PMMA Micropillars on the Surface-Driven Capillary Flow of Dyed Aqueous Ethanol in PMMA Microchannels
Abstract: In this work, dyed aqueous ethanol (60% ethanol, 40% dyed water) is prepared as the working liquid. The effect of surface modification on the microfluidic flow of aqueous ethanol is studied in the polymethylmethacrylate (PMMA) devices. The effect of surface area to volume ratio on microfluidic flow of aqueous ethanol is also studied. The effect of microfluidic friction on microfluidic flow of aqueous ethanol is also studied. This work will …
Published in Journal of Catalyst & Catalysis · Vol. 5, Issue 2, 2018 · pp. 1–4 Read article
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Experimental Demonstration on the Leakage-Free Surface-Driven Capillary Flow of Red Dye
Abstract: In this work, two individual SU-8 based glass microfluidic devices are fabricated by the maskless lithography and indirect bonding technique. Commercially available red-colored food dye is used as the working liquid. Microfluidic leakage is observed between the glass lid and SU-8 based microchannel substrate due to the improper indirect bonding technique. Leakage-free surface-driven capillary flow is observed due to the proper indirect bonding technique. CMOS camera is used to capture …
Published in Journal of Catalyst & Catalysis · Vol. 5, Issue 3, 2018 · pp. 8–11 Read article
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Effect of PMMA Micropillars on the Surface-Driven Capillary Flow of Dyed Aqueous Isopropyl Alcohol in PMMA Microfluidic Devices
Abstract: In this work, dyed aqueous isopropyl alcohol [60% isopropyl alcohol (IPA), 40% dyed water] is prepared as the working liquid. The effect of surface modification on the microfluidic flow of aqueous isopropyl alcohol (IPA) is studied in the polymethylmethacrylate (PMMA) microfluidic devices. The effect of surface area to volume ratio on microfluidic flow of aqueous isopropyl alcohol is also studied. The effect of microfluidic friction on microfluidic flow of aqueous …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 2, 2019 · pp. 44–47 Read article
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Short Review on the Probability of Carbon Nanotube Based Nanofluidics in Fluid Mechanics
Abstract: In this short review, author has briefly introduced the subject named as nanofluidics. Also, author has provided a short review on passive (surface-driven) capillary flow related to microfluidics. The effects of channel aspect ratio, surface wettability, liquid viscosity, effective viscosity, centrifugal force, and bend angle, are described to control the passive capillary flow in microfluidic devices and systems. Author has demonstrated the difference between leaky-device and non-leaky device in microfluidics. …
Published in Journal of Microwave Engineering and Technologies · Vol. 7, Issue 3, 2020 · pp. 14–17 Read article
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Short Report on Polymer Based Automated Fluid Machines for Applications in Microfluidics
Abstract: In this experimental work, a couple of gradual expansion microchannels are fabricated by polymethylmethacrylate (PMMA) using the maskless lithography, hot embossing lithography and direct bonding technique. Dyed ethylene glycol and dyed water are the prepared working liquids. The CMOS camera catching 25 frames per second with a corresponding time-scale resolution of 0.04 second is used to record each surface-driven microfluidic flow of dyed ethylene glycol and dyed water in the …
Published in Journal of Materials & Metallurgical Engineering · Vol. 11, Issue 2, 2021 · pp. 23–28 Read article
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Recording of Surface-Driven Capillary Flow inside the Polymeric Microchannel Coated with Diamond like Carbon
Abstract: In this experimental work, author has fabricated a single polymeric microfluidic device by maskless lithography, hot embossing lithography and direct bonding technique. Author has coated the diamond like carbon inside the microchannel by plasma enhanced chemical vapor deposition system. Author has recorded the surface-driven microfluidic flow of dyed water in the fabricated device. The meniscus profile is recorded during the surface-driven microfluidic flow. This research work may be useful to …
Published in Journal of Microelectronics and Solid State Devices · Vol. 7, Issue 3, 2020 · pp. 8–11 Read article