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39 articles for “L1-A”
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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Nanotechnology Application in Neural Growth Support System
Abstract: With its ability to transfer electric impulses, make contact with neurons, and mimic the environment of neurons, carbon nanotubes have been intriguing candidates for the development of scaffolding that could promote neuronal growth and division. In order to encourage the growth and development of human brain cells, the researchers developed biodegradable composite scaffolding comprised of interconnected carbon nanotubes dispersed in the poly-L-lactic acid substrate. To imitate the guiding inputs of …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 2, 2022 · pp. 47–55 Read article
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Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
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Switching in Bilinguals: Evidence from Forward and Backward Switching Tasks Across Visual and Auditory Modality
Abstract: Bilingualism refers to the use of two languages on a day-to-day basis. Defining bilingualism operationally is complex due to the heterogeneity associated with it. Proficiency in the second language can vary on an individual basis. Bilinguals can be classified as balanced or dominant, high proficient or low proficient based on the proficiency levels. The effect of bilingual proficiency on executive functions has been studied extensively. The current study explored the …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 19–23 Read article
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Time Multiplexed Binary Offset Carrier (TMBOC) Transmitter with Polarimetric Interferometric Synthetic Aperture Radar (Pol-InSAR)
Abstract: This paper provides insights into Time Multiplexed Binary Offset Carrier (TMBOC), a modulation technique employed in satellite navigation systems, specifically designed for GPS L1C. TMBOC improves signal correlation properties by time-multiplexing Binary Offset Carrier (BOC) (1, 1) and (6, 1). The text discusses various TMBOC models, including spectral representations and power distributions. Performance analysis reveals the potential of TMBOC signals in achieving superior tracking accuracy and interference resistance compared to …
Published in International Journal of Satellite Remote Sensing · Vol. 4, Issue 1, 2026 · pp. 34–49 Read article
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Contact Stress Analysis of Needle Roller Bearing Used in Synchromesh Gear Box
Abstract: The optimum selection of a bearing generally depends on particular application such as to transfer loads between the rotating and stationary members, and to permit free rotation. From among the wide range of bearings available in the market today has various considerations, such as the load-carrying capacity, the life of the bearing, and the working rotational speed need to be considered before a suitable bearing can be selected. Here for …
Published in Trends in Machine design · Vol. 5, Issue 1, 2018 · pp. 5–20 Read article
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Effect of Sustained and Selective attention paradigm in Recalling task: a Cross-Language Study
Abstract: Attention is the ability to channelize the resource towards the stimulus. Sustained attention refers to the process of holding attention for a considerable span of time while selective attention refers to the ability selectively channelize the attention to an selected set of stimulus governed by instructions. This task would require the selective inhibition of the irrelevant stimulus. The current study was carried out with the aim of investigating the sustained …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 1–6 Read article
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Synthesis, Characterization and Antibacterial Activity of Mono- and Binuclear Co(II) and Cr(III) Mixed-Ligand Complexes Derived from α-Amino Acid and 1,10- Phenanthroline with 1,3-Diaminopropan as a Spacer
Abstract: Mixed-ligand complexes of Co(II) and Cr(III) ions were synthesized from the reaction of metals chloride salts with α-amino acid (H2L1) as a primary ligand and 1,10-phenanthroline (L2) as secondary ligand. The ligand 2-(benzo[d]thiazol-2-ylamino)-2-(2-hydroxynaphthalen-1-yl) acetic acid (H2L1) has been synthesized from the condensation reaction of inobenzothiazol with 2-hydroxy-1-naphthaldehyde in the presence of HCN as three components–one pot reaction. H2L1 considered as a tridentate chelater of ONO-coordination binding type toward the metals, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 107–120 Read article
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DNA Binding and Cleavage Studies of Cobalt Complexes Containing Bioactive Mixed Ligands
Abstract: The complexes containing bioactive ligand of the type [Co(L1L2)] (PF6)2 complex (1) (where L1=1,10-phenanthroline and L2 = N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine (almotriptan) in 1:1 molar ratio of ligands) and [Co(L1L3L4)] (PF6)2 complex (2) (where L3=4H-1,2,4-triazol-4-amine, L4=1H-benzimidazole-2-thiol and the ligands are in the ratio 1:1:1, were synthesized and characterized. The DNA binding property of the complexes with calf thymus DNA has been investigated using absorption spectra, viscosity measurements and thermal denaturation experiments. The intrinsic …
Published in Emerging Trends in Chemical Engineering · Vol. 1, Issue 1, 2014 · pp. 49–56 Read article
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Parametric Optimization of TIG Welding on AISI-304 Stainless Steel Plate by Taguchi based RSM Method
Abstract: The effect of process parameters of TIG welding like the present work focuses the findings of an experimental investigation into the effects of Welding current, Gas flow rate, Electrode diameter, and Root gap on the bead geometry of AISI-304. It is found that the process parameters considered affected the mechanical properties with great extent. Taguchi methodology is used to analyze the effect of each welding process parameters and optimal process …
Published in Trends in Machine design · Vol. 4, Issue 2, 2017 · pp. 30–40 Read article
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Artificial Neural Network Modelling to Optimize Micro-Drilling Parameters of ECDM of Developed Novel Zn/(Ag+Fe)-MMC
Abstract: Several engineering fields have increased their use of metal matrix composites (MMCs) in the past few years. Due to the increase in composites, the demand for accurate machining has also become important. Specifically, pertaining to biomaterial applications, accuracy factor with desired surface finish is critical. While the near-net shape manufacturing process has advanced, MMCs frequently require post-mould machining to achieve surface quality, and dimensional tolerances. In the present study, a …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 01–13 Read article
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Effect of Drilling Process Parameters on Surface Roughness of LM6/B4C/Fly Ash Hybrid Composites
Abstract: This research seeks to assess the effect of process variables such as feed rate (FR), spindle speed (SS), drill material (DM) and reinforcement (R%) on surface roughness (SR) when drilling LM6/B4C/Fly ash hybrid composites. The stir casting process was used to fabricate the LM6/B4C/Flyash hybrid composites utilizing LM6 aluminum alloy as the matrix material and B4C/Fly ash as strengthening materials. Experiments were carried out using an L18 orthogonal array (OA) …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 898–906 Read article
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Drilling Parameters Optimization in LM6/B4C/Fly ash Hybrid Composites by Taguchi Technique
Abstract: Aluminium matrix composites (AMCs) are challenging to machine due to its abrasive characteristics. Because of the broad adoption of MMCs, it is vital to create sufficient equipment to facilitate efficient manufacturing. The current study utilizes signal-to-noise ratio (S/N) analysis to determine the ideal machining parameters for drilling AMC’s. The goal with this study is to investigate the effect of feed rate (FR), drill type (D), speed (SS), reinforcing material R …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 890–897 Read article
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Experimental Investigation Mechanical Behaviour of Composite Made by Carbon Fibre Mixed with Zro2 and Phenolic Resin
Abstract: Composites are one of the major research criteria in aerospace technologies to fulfil the present needs. Addition of materials to carbon fibers without increasing of weight of the parts Nano and micro fillers have its own criteria in improving mechanical properties. ZrO2 particles added to carbon fibers can improve the strength with a light add up in density. Present study focused on the mechanical behavior of zirconium oxide addition to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 562–573 Read article
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Optimization of Machining Parameters of EN-27 Material Using Wire Electric Discharge Machining (WEDM)
Abstract: The optimization of Wire Electrical Discharge Machining (WEDM) parameters for EN-27 alloy steel, a high-strength material widely utilized in mechanical and structural applications, is the subject of this study's methodical analysis. Due to its hardness and poor machinability by conventional methods, WEDM is preferred for achieving precise dimensional accuracy and surface integrity. The primary objective of this work is to enhance machining performance by identifying optimal process parameters influencing Material …
Published in Journal of Production Research & Management · Vol. 16, Issue 1, 2026 · pp. 32–36 Read article
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Thermal Interaction Analysis Between Flexible Magnetic Abrasive Brush and Aluminium Alloy During Single-Pole MAF
Abstract: Magnetic Abrasive Finishing (MAF) is a precision surface‐finishing approach that employs magnetic abrasive particles (MAPs) within a managed magnetic field to eliminate micro-level material and enhance surface condition. In the finishing process, the friction created between the workpiece and the flexible magnetic abrasive brush (FMAB) leads to heat accumulation, which may badly affect the surface integrity. This study focuses on investigating the temperature distribution at the FMAB–workpiece interface to decrease …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1906–1918 Read article
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An Experimental Investigation on the Characterization of Al6061-Polymer Adhesive Joint by Design of Experiment
Abstract: Aluminium alloys and polymers are the light-weight materials extensively used in structural, aero-space, automobile and marine applications. Al6061 alloy and nylon 6 were joined through the adhesive bond and their characteristics were analyzed. However, joining of these dissimilar materials for the evolution of hybrid engineering structures were complex because of their difference in physical, chemical and mechanical behaviours. The Taguchi’s, Design of Experiment were conducted on the various mixture of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 206–219 Read article
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A Study on Fracture Sem Analysis by Optimization of FSW When a Composite Material Al 6061 Mixed with Fly Ash is Done with Cooper Using Anova Method
Abstract: The current study aims to examine how different parameters in friction stir spot welding influence hardness and tensile strength, while identifying the most suitable parameter combinations to enhance the overall quality of the fabricated components. The experimental work involves joining dissimilar materials, where one specimen consists of Aluminum alloy 6061 reinforced with 10% fly ash, and the other is a copper alloy. Various process conditions are altered during testing to …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 1–5 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article
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Thermal Performance Analysis and Optimization of Pin-Fin Heat Sink Using CFD, Taguchi Method, and Machine Learning
Abstract: Efficient thermal management is essential for improving the performance and reliability of modern engineering systems and electronic devices. This study presents the design, simulation, and optimization of a pin-fin heat sink using SolidWorks for three-dimensional modeling and ANSYS for thermal and computational fluid dynamics (CFD) analysis. Four different pin-fin geometries, namely square, pentagon, octagon, and circular fins, are considered to evaluate their thermal performance under varying operating conditions. Aluminum is …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 8–20 Read article