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89 articles for “Gastrointestinal”
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Prevalence and Associated Risk Factors of Major Gastrointestinal Nematodes of Cattle in Hawassa City.
Abstract: Gastrointestinal nematodiasis is a major constraint of livestock production causing huge economic loss to livestock sector of a country. A cross-sectional study aimed to assess prevalence of major gastrointestinal nematodes and associated risk factors was conducted from February 2021 to November 2021 in Hawassa city. In the study, fecal samples were collected from randomly selected 384 cattle and coprological examination was employed by using floatation method. The study result revealed …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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Animal Gastrointestinal Tract in Animals Health
Abstract: The gastrointestinal tract's (GIT) functionality and health are essential elements that influence animal productivity. Since the management of GIT growth and health involves numerous complicated systems, it is critical to have a better understanding of these interconnections in order to create strategies for modulating GIT functioning and health in the perspective of better animal performance. Within in the animal scientific community, this term of "gut health" has sparked considerable interest. …
Published in International Journal of Animal Biotechnology and Applications Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Evaluating the Role of Apple Cider Vinegar in Managing Semaglutide-Induced Gastrointestinal Disturbances: A Systematic Review
Abstract: Background: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is highly effective in treating type 2 diabetes and obesity. However, its use is often associated with gastrointestinal side effects, including nausea, vomiting, and diarrhea, which may impact patient compliance. Objective: This systematic review aims to evaluate the evidence regarding the management of semaglutide-induced GI symptoms and assess the potential role of apple cider vinegar (ACV) as a complementary treatment. Methods: A …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Medicinal Pteridophytes of Himachal Pradesh: Exploring Their Role in Alleviating Respiratory and Gastrointestinal Disorders
Abstract: Pteridophytes, comprising a diverse group of vascular cryptogams, have been widely used in traditional medicine for their medicinal properties. The therapeutic potential of different medicinal pteridophytes in treating gastrointestinal and respiratory conditions is investigated in this study. Their bioactive substances, including flavonoids, alkaloids, tannins, and saponins, which have anti-inflammatory, antibacterial, and antispasmodic properties, are highlighted by both traditional knowledge and recent research. Specific species, such as Adiantum capillus-veneris (maidenhair fern), …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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Necrotizing Enterocolitis (NEC): A Devastating Neonatal Gastrointestinal Disorder
Abstract: Necrotizing enterocolitis (NEC) represents a formidable challenge in neonatal medicine, particularly afflicting premature infants with its characteristic features of severe intestinal inflammation and necrosis. Despite advancements in neonatal care, NEC continues to exact a heavy toll, standing as a prominent cause of morbidity and mortality in this vulnerable population. Its multifaceted etiology, encompassing prematurity, enteral feeding practices, alterations in microbial colonization, and episodes of intestinal ischemia, underscores the complexity of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 78–83 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Nutritional Significance of Milk Minerals
Abstract: Mineral constituents occurs in milk and dairy products in form of organic ions and salts; however several minerals are also found associated with major milk constituents like fat, protein, carbohydrate and nucleic acid. Milk contributes significantly to the human dietary requirements of several minerals including calcium, magnesium, potassium, zinc, and phosphorus. Milk also contains some other minerals like chloride, selenium, etc in relatively less but significant amount. Numerous factors, including …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 7–19 Read article
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Pharmaceutical Syrup Formulation Enhancing Bioavaibility and Patient Compliance
Abstract: Pharmaceutical syrup formulations are crucial for drug delivery, especially in pediatric and geriatric populations. However, challenges, such as bioavailability, stability, and patient compliance due to factors, like taste and viscosity, must be addressed. Strategies to enhance bioavailability include solubility enhancers, nanoparticle systems, and advanced techniques like solid dispersions and emulsions. Palatability plays a critical role in patient compliance, with flavoring agents, sweeteners, and texture modifications improving acceptability. Innovations, like controlled-release …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 1–6 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Enhancing Peptic Ulcer Therapy: Innovations in Mucoadhesive Drug Delivery
Abstract: Peptic ulcer disease is still a sincere gastrointestinal demand makes medication administration difficult because of the harsh and changing stomach environment. This paper investigates the potential of using mucoadhesive drug delivery devices to improve the accuracy and effectiveness of peptic ulcer therapies. Due to the inherent characteristics of mucoadhesive drug delivery systems, localized and sustained drug release is made possible by their extended contact and adherence to the gastrointestinal tract's …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 62–76 Read article
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In Silico Analysis and Molecular Docking Studies of COX-2 Inhibitors for Anti-Inflammatory Activity
Abstract: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat pain, lower fevers, and control inflammation, they frequently cause gastrointestinal side effects because they inhibit the COX-1 and COX-2 enzymes. Despite their effectiveness and lack of gastrointestinal side effects, selective COX-2 inhibitors have been linked to cardiovascular risks. To find new COX-2 inhibitors that are safer and more effective, this study uses in silico techniques, such as molecular docking and …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 38–55 Read article
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Evaluation of Prescribing Pattern of Drugs in Hemodialysis Patients
Abstract: Background: Patients undergoing hemodialysis often exhibit a high level of dependency and frequently present with multiple co-morbid conditions Chronic kidney disease (CKD) poses a significant global public health challenge, with its association with numerous complications. Prescribing medications appropriately for individuals with CKD presents a substantial challenge. Objective: The study aimed to assess the prescribing patterns of drugs in hemodialysis patients. Results: Out of the total 82 selected patients, 42 (51%) …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Design and Development of Novel Floating Drug Delivery Systems
Abstract: Recent advances in science and technology have greatly aided in the creation of novel drug delivery methods, especially in addressing physiological issues including irregular stomach emptying times and brief stomach residence periods. Long-term stomach absorption is the goal of gastro-retentive dosage forms (GRDF). Floating drug delivery systems, expanding or swelling systems, polymer-based bioadhesive systems, high-density systems, and other ways that postpone stomach emptying are just a few of the techniques …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Effect of Polymer Crosslinking on Drug Release Kinetics
Abstract: In order to improve treatment effectiveness and minimise adverse effects, polymer-based drug delivery systems are often used to produce regulated and sustained drug release. Polymer crosslinking, which alters the structural, mechanical, and degrading characteristics of the polymer matrix, is one of the key elements affecting drug release kinetics. The porosity, swelling behaviour, and rate of degradation of the polymer are all impacted by the crosslinking process, which may be accomplished …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 636–647 Read article