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8 articles for “Disease predisposition”
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Evaluation Tumor Necrosis Factor-α (TNF- α) Levels in Patients with Rheumatoid Arthritis
Abstract: Background: RA is an inflammatory, long-term autoimmune illness, that is impacted by external variables, according to a report from the World Health Organization. Women are 2-3 times more likely than men to develop RA, though this difference diminishes with older age at onset. Aim: The purpose of this study is to assess the significance of TNF-α concentrations in the predisposition to rheumatoid arthritis. Methods: The research project enrolled 100 patients …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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A Comprehensive Review on Long-term Care Policies for Intellectual and Developmental Disabilities
Abstract: Intellectual disability (ID) is a neurodevelopmental difficulty that affects both intellectual functioning and adaptive behaviour. The term IDD describes a broad range of long-term disorders that are caused by either physical or mental deficits. These disorders can influence numerous facets of life, such as self-care, social skills, communication, and education. This condition affects social and practical abilities daily. Conditions like cerebral palsy, Down syndrome, and autism spectrum disorder, Genetic predispositions, …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 36–42 Read article
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Ulcerative Colitis- An Ayurvedic Review And Treatment – A Case Study
Abstract: Ulcerative colitis (UC) is a chronic autoimmune disease that causes inflammation and ulcers of the Large intestine. It is one of the most common GI disorder. Usually the pain affects only the intestinal mucosa and sub mucosa, causing small ulcers in the intestinal lining called ulcers. In most of patients, the disease begins from the anus and continues to spread. Its pathogenesis is multi factorial and includes genetic predisposition, epithelial …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 31–39 Read article
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To Rule Out the Efficacy of Haridradi Drugs in Respiratory Allergic Disorders in the Childrens.
Abstract: Allergic diseases in children have increased significantly in recent years and they are a major cause of morbidity in the children. Although there is a genetic predisposition, exposure to allergens i.e pollens, irritants, infections, diets and inhalant will determine the sensitization. At present, the best approach to the children who are at high risk for the development of allergies is to introduce environmental and dietary control and adopt early measures …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 53–60 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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Climate-Induced Infertility in Dairy Cows: Pathways, Challenges, and Solutions for Sustainable Dairy Development
Abstract: Climate change has emerged as a significant challenge to dairy production, with profound implications for reproductive performance in dairy cows. The interplay of rising temperatures, fluctuating rainfall patterns, and increased frequency of extreme weather events disrupts key physiological, nutritional, and behavioral processes essential for fertility. Heat stress alters hormonal balance, impairs oocyte and embryo quality, reduces estrus expression, and affects pregnancy outcomes. Concurrently, climate-induced nutritional deficits, immune suppression, and increased …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 Read article