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6 articles for “Cardio-oncology”
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Pharmacogenomics and Precision Medicine: An Evolving Analytical Clinical Tools for Future Medicine – A Narrative Review
Abstract: The term Pharmacogenomics is coined as an emerging field that exactly examines how the genetic variations influence the individual responses towards medications. This discipline in turn integrates the pharmacology as well as genomics to facilitate the personalized medicine, encouraging the healthcare providers to tailor their drug therapies based on individual patient’s genetic profile. Key applications include optimizing drug efficacy, minimizing adverse effects, and enhancing treatment outcomes across various medical fields, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 44–52 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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Polymer Chemistry and Composite Materials in Biomedical Applications
Abstract: The integration of polymer chemistry and composite materials has revolutionized biomedical applications. Recent advancements in polymer synthesis, functionalization, and nanotechnology have further expanded their applications, leading to significant improvements in biocompatibility, biodegradability, and mechanical performance. These polymeric carriers protect bioactive compounds from enzymatic degradation, enable controlled drug release, and improve therapeutic efficacy. The integration of polymer chemistry with nanotechnology has enabled the development of highly efficient, targeted therapeutic systems that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 413–419 Read article
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FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
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Cancer Tumor Markers And Its Latest Trends
Abstract: Almost one in six deaths occurs due to abnormal cell division; these cells are termed cancer cells in general. Cancer cells collaborate to multiply and metastasize. Our aim is to awaken awareness in people to understand their bodies and motivate them for early diagnosis,as cancer is the second leading cause of death after cardiovascular disease. The human body is a marvellous creation in nature; in response to cancer, it creates …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 25–38 Read article