Search
338 articles for “Cancer Cell”
-
Two-chamber Medical Electroflotator for Cleaning of the Lymph of Cancer Patients from Toxic Substances and for the Destruction and Removal of Cancer Cells Contained in It
Abstract: Existing devices for cleaning of the lymph of patients with liver cirrhosis or hepatitis from a high concentration of toxic substances, contained in it, do not allow cleaning the body of patients from these toxic substances. In addition, these devices require the patient's lymph to be purified in a discrete mode, i.e., all the patient's lymph, without which the patient remains, is purified for a sufficiently long time, and after …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 21–27 Read article
-
The Toxic Substances and Cancer Cells Lymphosorption using Hydrogen and Oxygen Bubbles Photoelectroflotation Process Powered by Light Energy
Abstract: This study presents the application of a new developed method of hydrogen and oxygen bubbles photoelectroflotation and a specially developed complex: photoelectrolyzer + bicameral flotation cell for cleaning of the lymph of a patient with liver cirrhosis or hepatitis from toxic substances and for destroying and removing cancer cells contained in it, by adhesion of microdispersed negatively charged hydrogen bubbles, formed in the photoelectrolyzer during the arising photoelectrolysis of water, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 12, Issue 1, 2023 · pp. 6–20 Read article
-
A Study of Cancer Cell through Sequencing Model
Abstract: The condition to cure of cancer is presented in this paper. Curable, incurable, and destroyable conditions are formulated by the sequencing theory. The role of real number is generalized on the proposed method. The sequencing theory is applied on the cancer cell. The proposed model presents the computational overview of the cancer cell in context to measure and cure. There is set of conditions carried the time and cell sequence. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 3, 2021 · pp. 52–54 Read article
-
A Model for Destroying Cancer Cell
Abstract: Cancer is studied in this paper by the optimization technique. By this technique, cancer cell growth rate can be controlled. To minimize the growth rate of the cancer cell is the objective of this paper. The linear programming is used here to control the cancer. An anticancer model is presented in this paper based on linear programming problem. The formulation of anticancer based on the finite decision variables. There is …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 3, 2021 · pp. 1–4 Read article
-
Magnetic ZnxFe2–xO3 Nanoparticles Enhanced Nanobiosensor Integrated with MOSFETs for Efficient Detections of Biomolecules and Cancerous Cells
Abstract: The human brain is mostly responsible for intelligence and consciousness. An artificial equivalence of this action is nanobiosensor, which is used in artificial intelligence. The need for nanodiagnostics platforms for detecting diseases at the genetic, molecular, and cellular level has triggered the development of nanobiosensors integrated with MOSFETs. This device enables simple, inexpensive rapid tests, accurate imaging methods, and accurate molecular diagnosis at point-of-care (POC). This device is seen as …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 3, 2024 · pp. 33–44 Read article
-
Utilizing circulation-derived cancer cells to evaluate patients with surgically treated stages I–IIIA NSCLC throughout the preoperative phase
Abstract: Context: When a tumor is considered resectable, surgery is viewed as the primary treatment approach for both early-stage and locally advanced non-small cell lung cancer (NSCLC). One of the most exciting areas of cancer research in the past ten years is liquid biopsy, which offers a practical non-invasive method for cancer detection and tracking. Circulating tumor cells (CTCs) have been linked to a worse prognosis and increased chance of relapse …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 17–28 Read article
-
Change of Capacitance in Cancerous Cell
Abstract: Cancer is a genetic disease. It is characterized by out of control growth of cell. It harms the body with its uncontrollable growth. Tumors that do not spread and show limited growth are generally considered to be benign. More dangerous are malignant tumors which can manage to divide and grow. They may be very dangerous and may cause death. Early detection of the disease helps in treatment and may save …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 1, 2015 · pp. 29–32 Read article
-
The Effect of Prepared Biochemical Compounds on Cancer Cells
Abstract: The effect of prepared biochemical compounds affecting cancer cells, where the chemical compounds are divided into two parts, some of which are treatment for cancerous tumors, and others activate cancer cells such as glucose and sugars, which increase the size of the cancerous tumor and its spread in the body. While chemotherapy usually refers to the use of antitumor drugs to treat cancer through a cytotoxic treatment method. It also …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 14–20 Read article
-
Transformation of Cancer Cell into Normal Cell by Group Theory
Abstract: Cancer is studied in this paper by theory of group. Cancer is incurable by indefinite rate of change in the cell. Here cancer is defined as the algebraic structure with some properties for finding the unique objective i.e. curing the cancer. Curing the cancer disease is possible by the transformation of every cancer cell into normal cell by the group postulates in this paper. The biological structure is transformed into …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 9, Issue 1, 2022 · pp. 30–32 Read article
-
In vitro Cytotoxicity of 17-Oxo-5-androsten-3β-yl esters against Liver, Neuroblastoma and Colon Cancer Cell Lines
Abstract: A tumor is abnormal growth of body tissue and steroidal derivatives represent a distinct class of antineoplastic agents. Positioning of the oxo group on the parental steroid skeleton has significant effect on the antineoplastic activity profile of the compounds. Recent work from our laboratory has also demonstrated the effectiveness of 17-oxo-5-androsten-3β-yl ester derivatives as potential antiproliferative agents and 5-alpha reductase inhibitors. The current study was undertaken to investigate the cytotoxicity …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 3, 2016 · pp. 23–27 Read article
-
Effect of Caffeic Acid on Glutathione Metabolism of MCF-7 and MDA MB-231 Breast Cancer Cells
Abstract: Increasing incidences of breast cancer at alarming rates with treatment strategies having an overall detrimental effect on the patients led to investigating the potential of phytochemicals as anti-tumorigenic agents. Caffeic acid, an antioxidant and anti-tumorigenic phytochemical, has been tested on MCF-7(hormone responsive) and MDA MB-231(hormone-independent) breast cancer cell lines. Alterations in the levels of intracellular glutathione (GSH) in both cell lines due to exposure to the drug are the primary …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 1, 2022 · pp. 14–22 Read article
-
Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
-
Inhibition of MDA-MB-231 Breast Cancer Cell Proliferation by Simple Diphenyl Chalcone and Its Chlorinated Derivatives
Abstract: The pharmacological activities of chalcones and their derivatives are well documented. Chalcones are an important class of natural products that occur in edible plants such as spices, tea, fruits and other vegetables. In vitro studies have shown that chalcones inhibit proliferation of breast cancer cells by inducing apoptosis and blocking cell cycle progression. Substituent effects, namely, adding electron-withdrawing substituents to the chalcone structural motif, and the extents to which those …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 7–12 Read article
-
Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
-
Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
-
Long non-coded RNA, cancer, immune cells, tumor micro-environment, immuno-oncology, immune escape, cancer-immune cycle, lncRNA signature
Abstract: Developing data from current research reveals fresh insights into the roles played by long non-coding RNAs (lncRNAs) in immuno-oncology. Long non-coding RNAs (lncRNAs) not only influence the aggressiveness of cancer cells but also play a crucial role in controlling different immune cells and stromal cells, which in turn changes the tumor micro-environment and impacts anti-tumor immunity. The significance of predictive indicators derived from long non-coding RNAs (lncRNAs) is underscored by …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 7–26 Read article
-
In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
-
Lymph Purification for Liver Cirrhosis Patients’ Treatment
Abstract: The existing methods of lymph purification do not permit to clean the organism of patient with liver cirrhosis from an increased concentration of toxic substances contained in his lymph. In addition, the process of cleaning of the lymph in these methods takes a long time, during which the patient remains without lymph, waiting for clean lymph that sharply weakens him and in extraordinary cases can lead to death. The presence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 11–17 Read article
-
Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
-
Induction of G1 Phase Cell Cycle Arrest and Apoptosis in Breast Cancer MCF-7 Cells by Sulphonamide Derivative CID-6861424
Abstract: Breast cancer is most frequently detected and leading cause of cancer death in women worldwide. 80% of the breast cancer are estrogen receptor positive and the presently available drugs are ineffective either due to intrinsic resistance or due to acquired resistance. Sulfonamide compounds are a class of compounds showing activities like, antibacterial, antiviral including antitumor. In the present study we have investigated the anti-cancerous activity of sulfonamide derivative CID-6861424 on …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 1–17 Read article