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6 articles for “Aldosterone”
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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Review On Primary Failure Adrenocortical Insufficiency
Abstract: Adisson's disease, also known as adrenal insufficiency, is an uncommon ailment that happens when the body doesn't generate enough of a number of hormones. When someone has Addison's disease, their adrenal glands typically generate too little aldosterone and too little cortisol. In industrialised nations, autoimmune attacks on the adrenal cortex are the main cause of Addison's disease; prevalence estimates in Europe range from 93-220 per million. The damage to your …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 17–22 Read article
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A Systematic Review of Method Development and Validation for Ramipril Analysis Using Hplc in Cardiovascular Research
Abstract: The field of analytical chemistry encompasses a variety of methods that are crucial in determining the chemical composition of different substances. UV-visible spectroscopy and high-performance liquid chromatography (HPLC) are two widely utilized methods that are the subject of this article. UV-visible spectroscopy uses the Beer-Lambert law to quantify light absorption, which can provide information about the concentration of absorbing species. The method is based on how light and matter interact, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 37–44 Read article
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An Overview on Resistant Hypertension: Pathophysiology, Diagnosis, and Management
Abstract: Hypertension is a universal health issue, which is an utmost attributor for the weight of cardiovascular diseases when BP leftovers resistant or stubborn to therapeutic events. Notwithstanding the progressive growth in the antihypertensive therapy, the incidence of resistant hypertension is assessed to be less than 5% of the hypertensive inhabitants. Resistant hypertension is well-defined as blood pressure that leftovers over head the goal line in meanness of the simultaneous usage …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 16–30 Read article
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A Review on the Clinical and Pathological Significance of Prorenin Receptor [(P)RR]
Abstract: The (pro)renin receptor (P)RR discovery, which is a novel constituent of Renin Angiotensin-Aldosteron System (RAS) has brought renin and (pro)renin back into spotlight. The (P)RR binds both renin and its inactive precursor (pro)renin, this binding triggers a cascade of intracellular signalling that eventually leads to upregulation of the expression of profibrotic genes, potentially leading to pathogenesis of cardiac and renal fibrosis, growth and remodelling. Clinically, it is also seen that …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 11–17 Read article
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Docking Studies on Some Benzimidazole and Triazole Analogues as Antihypertensive Agents
Abstract: The incidence rate of hypertension continues a phenomenal rise and so, there is a growing need to identify novel therapeutic agents with improved efficacy and reduced side effects. In these circumstances, drugs acting on multiple targets could offer superior efficacy profiles compared with single target drugs. Some molecules have been designed using rational drug design approach and evaluated by performing docking studies. Targets used were an angiotensin-converting enzyme, angiotensin receptor, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 2, 2018 · pp. 37–39 Read article