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478 articles for “ADME”
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The Role of Generative AI in Enhancing Administrative Efficiency: Innovations in Workforce Support Systems
Abstract: Generating AI is the primary form of artificial intelligence that disrupts administrative work across multiple industries by redesigning and promoting the automation of traditional tasks and improving the workforce efficiency of decision-making. In a conventional setting, executive positions have been equally associated with paper-bound responsibilities, common with tedious activities like appointment making, filing, data input, etc. However, improvement in the area of generative AI makes these natural functions assignable, thus …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 47–68 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Improving the Performance of Self-compacting Concrete Using Optimized Admixture Combinations
Abstract: This study explores the influence of various admixture combinations on the performance of Self-Compacting Concrete (SCC), with an emphasis on its flow behavior, compressive strength, tensile strength, flexural strength, and resistance to impact. Various admixtures, including Air-Entraining Agent (AEA), Water-Reducing Plasticizer (WPC), Retarder (RET), and Accelerator (ACC), were incorporated into the SCC reference mix (SP + VMA) to evaluate their impact on SCC performance. A series of tests—such as slump …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 3, 2024 · pp. 81–89 Read article
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Clinical and Administrative Processes in Contemporary Dental Practice
Abstract: Maintaining operational efficiency, providing patients with high-quality oral healthcare, and guaranteeing patient pleasure all depend on a dental clinic operating well. This article looks at the administrative procedures, clinical workflow, and organizational structure that go into running a dental clinic on a daily basis. Patient scheduling, infection control procedures, dental equipment management, staff roles and duties, record-keeping, and adherence to legal and ethical standards are some of the important topics …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 19–24 Read article
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Knowledge and Practice of Self-Administration of Insulin Injections among Diabetic Patients
Abstract: High blood glucose levels are a hallmark of diabetes mellitus, a chronic and crippling illness. According to estimates from the World Health Organization (WHO), 530 million persons globally have diabetes. Diabetes management requires education, and educating patients how to administer insulin injections on their own can give them the power to take charge of their health. The purpose of this study was to evaluate diabetic patients who visited the diabetes …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 29–33 Read article
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Molecular Docking, QSAR Modeling, and ADMET Evaluation of Novel Pyrazolo-Pyrimidine Derivatives as Potential CDK-2 Inhibitors for Cancer Therapy
Abstract: Cyclin-dependent kinase-2 (CDK-2) is an essential regulator in cell cycle progression and is an important therapeutic target in cancer drug development. In the present study, an integrated computational approach involving molecular docking studies, QSAR modeling, ADMET prediction, and artificial intelligence-based analysis was used to identify pyrazolo-pyrimidine derivatives as potential CDK-2 inhibitors. Based on the molecular docking results, it was found that selected compounds exhibited high binding affinity towards the ATP …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Design and Development of a Case Study on a Simple Banking System (SBS) by Applying the Concepts of Django Models, Views, Templates, Admin Interfaces, and Forms Using Full-Stack Development Framework
Abstract: The purpose of this case study is to develop and demonstrate various facilities and features available in full-stack development using Django by considering a simple example of a banking system. The concepts of Django Models, Views, Templates, Admin Interfaces, and Forms are used to ensure this case study utilizes all features of the framework to make it the complete miniature product. In addition, a well-documented report, and various test-cases related …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 26–36 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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Durability Assessment of Self Compacting, Self Curing Concrete Incorporating Crushed Rock Powder and Mineral Admixtures
Abstract: Curing plays a crucial role in achieving the desired strength, characteristics, and durability of concrete. Negligent curing practices can lead to adverse effects on hydration and mechanical properties of concrete. In recent times, self-curing concrete has gained significant attention due to its potential in reducing water loss through the use of self-curing agents. The Present Research study focus on investigation on durability characteristics of self-curing self-compacting concrete using crushed rock …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 25–35 Read article
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Streamlining Hostel Management: An Innovative Online System for Efficient Administration
Abstract: This article presents a hostel administration system built with XAMPP, which integrates Apache, MySQL, PHP, and Perl into a user-friendly package, in response to the tourism industry's increasing demand for improved management. The system is made to make handling check-ins and check-outs, billing, and room assignment easier, among other hostel management duties. The Hostel Management Framework is an online program designed to oversee various operations in a hostel. This concept …
Published in International Journal of Electronics Automation · Vol. 2, Issue 2, 2024 · pp. 26–33 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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A Comparative Study to Assess the Level of Satisfaction with Nursing Care Services Among the Patients Admitted in the Selected Government and Private Hospital of District Mohali, Punjab
Abstract: Introduction: The global healthcare environment is undergoing significant transformation. Within this dynamic setting, nursing care plays a crucial role in patient outcomes. Today, patient satisfaction with nursing care is widely recognized as a key indicator of overall hospital service quality. Assessing patient satisfaction from a patient-centered perspective has become an essential part of modern quality management systems in hospitals. Since nursing care constitutes a fundamental part of healthcare delivery, its …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 9–16 Read article
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Effect of Nebulization With 3% Hypertonic Saline for Airway Clearance on Mechanically Ventilated Patients Admitted in ICUs of Pt. B.D. Sharma, PGIMS, Rohtak
Abstract: Background of the Study: The ability to breathe artificially prolongs life in many situations. Patients requiring mechanical breathing in the intensive care unit are more likely to have complications and even death due to a variety of interconnected causes. As a result, it became critical to rapidly ventilate in the safest and most efficient manner available. Intubated patients have benefited from nebulized suctioning, as it improves lung clearance and decreases …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 20–27 Read article
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A Study to Assess the Effectiveness of Cradle Hold Position on the Gratification During Breastfeeding Among Postnatal Mothers Admitted at Selected Maternity Hospitals in South Bangalore, Karnataka
Abstract: This study aims to assess the effectiveness of the cradle hold position on the satisfaction experienced during breastfeeding among postnatal mothers admitted at selected maternity hospitals in south Bangalore, Karnataka. The cradle hold position is a commonly used breastfeeding technique where the mother supports the baby's head with one hand and holds the baby's body with the other arm, bringing the baby's mouth to the breast. The level of satisfaction …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 30–36 Read article
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A study to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients admitted in intensive care units of a selected tertiary care hospital Ludhiana, Punjab
Abstract: Weaning is a gradual transition from full invasive ventilatory support to spontaneous ventilation with minimal support. This conducted to assess the effect of nature-based sound therapy among Mechanically Ventilated Patients admitted in Intensive Care units. An experimental design (randomized controlled trial) was used to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients.30 patients were drawn from the target population by using convenience sampling technique and …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Exploring DHCP Protocol Administration: A Packet Tracer Simulation Study
Abstract: The following functions of DHCP are included to lessen network administration: TCP/IP setting that is automated and centralized. the capability of centrally defining TCP/IP setups. the use of DHCP options to allocate a complete range of additional TCP/IP configuration values. DHCP runs at the application layer of the TCP/IP stack. Although this essay will concentrate on Windows NT, another advantage of DHCP is that it is compatible with a wide …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 2, 2023 · pp. 1–11 Read article
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Effectiveness of Deep Breathing Exercise on Respiratory Parameters Among Post Extubated Patients Admitted in ICUs
Abstract: Introduction: Deep breathing exercises may be used to restore lung oxygenation ventilation function and are anticipated to enhance respiratory parameters. Aim: This study was done to examine the effectiveness of deep breathing exercise on respiratory parameters among post extubated patients. Methodology: A quasi experimental (pre-test, post-test control group) with quantitative approach study was conducted to assess the effect of deep breathing exercise on respiratory parameters among 30 post extubated patients …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 25–31 Read article
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Experimental Study on Mechanical and Durability Properties of Concrete Using Mineral Admixtures
Abstract: This study explores the partial replacement of OPC with Fly Ash (FA), Rice Husk Ash (RHA), Glass Powder (GP), Palm Oil Fuel Ash (POFA) at varying percentages of 10%, 20%, 30% with the addition of 1% chemical admixture with water-cement ratio of 0.45. The influence of these replacements on the fresh properties, mechanical and durability properties is evaluated at 7, 28, and 56 days of curing. The results indicate that …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 148–160 Read article
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A Comparative Analysis of Factors Contributing to Relapse in Alcohol and Opioid Dependence Among Patients Admitted to Selected Hospitals in Ludhiana, Punjab.
Abstract: Introduction: Substance abuse involves the dangerous or detrimental use of psychoactive substances, such as alcohol and illegal drugs. The use of these substances can result in dependence syndrome, which encompasses a range of behavioral, cognitive, and physiological effects that arise from ongoing substance use. Objectives: This study was carried out to examine the factors linked to relapse in alcohol and opioid dependence among patients admitted to selected hospitals in Ludhiana, …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article