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4 articles for “1HNMR”
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Hydrotropes as effective reaction Media for the Synthesis of Chlorothiazide
Abstract: The paper describes the synthesis of Chlorothiazide. It is a thiazide diuretic (water pill). It decreases theamount of fluid in the body by increasing the amount of salt and water lost in the urine. It is also used tolower the blood pressure as antihypertensive and to decrease edema (swelling). The synthesis ofChlorothiazide was carried out using four different hydrotropes, the effect of hydrotropes on yield, rateconstant and activation energy at …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 3, Issue 2, 2012 · pp. 9–17 Read article
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Mono(acetylacetonato)zirconium(IV) Aryloxides: Synthesis, Reactivity and Thermoanalytical Investigation
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 A series of novel zirconium(IV) complexes, formulated as ZrCl3−n(acac)(OArI–V)n (where n =− 3; –OArI = OC6H4Cl-2, –OArII = OC6H4Cl-4, –OArIII = –OC6H3Cl2-2,4, OArIV = –OC6H3Cl2-2,6 and OArV = –OC6H2Cl3-2,4,6) were synthesized by reacting ZrCl3(acac) with corresponding substituted chlorophenols in separate experiments. The complexes were characterized by elemental analysis, molar conductance measurements, molecular weight determination, spectroscopic techniques (1HNMR and IR) and thermal …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 3, Issue 1, 2012 · pp. 6–16 Read article
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Synthesis, Characterization of Novel 5-(Dimethylamino) Naphthalene Sulfonamide Derivatives
Abstract: 5-(Dimethylamino) naphthalene-1-sulphonic acid was synthesized by methylation of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulphonyl chloride were synthesized by the chlorination of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulfonamide derivatives were synthesized by condensation of 5-(Dimethylamino) naphthalene-1-sulphonyl chloride and corresponding primary amines. There chemical structures were confirmed by I. R., 1HNMR and elemental analysis. Keywords: Synthesis, sulfonamides derivatives, 5-(Dimethylamino) naphthalene-1-sulphonic acid, 5-(Dimethylamino) naphthalene-1-sulphonyl chloride Cite this ArticleKhan Asif, Mishra Ritesh, Malvia Hitesh, et al. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 2, 2015 · pp. 1–5 Read article
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Synthesis and Characterization of m-Amino Pyridine Derivatives
Abstract: Background: The current study involves the synthesis and characterization of amino derivatives. In the current research study, a series of m-amino pyridine derivatives were synthesized using m-amino pyridine and carbonyl compounds and characterized further. The pyridine derivatives have shown to possess potent antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory antidiabetic, antioxidant, anthelmintic, anticonvulsant, antituberculous and so many other properties. Method: The condensation reaction of m-amino pyridine and carbonyl derivatives with ethanol is …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 1–6 Read article