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347 articles for “amines”
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Synthesis and Synergistic Effects of Ciprofloxacin Conjugated Zinc Oxide Nanoparticles
Abstract: Zinc oxide nanoparticles (ZnO NPs) are known as a multifunctional material because of its unique physical and chemical properties. The result of zinc oxide nano powder was characterized using various analytical techniques, such as UV-Vis spectroscopy, Fourier Transform Infra-Red (FTIR), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD) patterns. Synthesized zinc oxide nano powder was stored in dried form in the room temperature for further study. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 1, 2019 · pp. 61–71 Read article
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Protein-Tyrosine Phosphatase-1B (PTP-1B) Inhibitory Perspectives of Hydroxylated Chalcones: Exploration through Docking Studies
Abstract: The current research emphasized on exploring the Protein-Tyrosine Phosphatase-1 B (PTP-1B) inhibitory potentials of hydroxylated chalcone derivatives against PDB ID: 4I8N (PTP-1B in complex with an inhibitor [(4-{(2s)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl)sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid) by molecular docking approach using the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The current molecular docking analysis of some hydroxylated chalcone derivatives have presented a profound inhibition of the antidiabetic target PTP-1B by interacting with the amino acid residues …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 1, 2019 · pp. 4–8 Read article
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Polyphasic Characterization and Comparative Genomics of a Newly Isolated Strain of Kocuria soli from Wild Ass Sanctuary, Gujarat, India
Abstract: From soil sample collected from Little Rann of Kutch-Wild Ass Wild Life Sanctuary, Gujarat a bacterial strain that is non-motile, cocci in shape, obligate aerobic, gram positive, catalase and oxidase positive was isolated and named as strain JC486. Strain JC486T was related to Kocuria soli M5W7-7T (99.7%) belonging to genus Kocuria according to sequence similarity and comparison data of 16S rRNA gene. The strain JC486T had a G+C content (DNA) …
Published in Journal of Water Pollution & Purification Research · Vol. 9, Issue 3, 2022 · pp. 16–22 Read article
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A Novel Approach of Protein Peptide Drug Delivery System
Abstract: Protein and peptides perform vital functions in body and are essential for life. They show various roles as therapeutic agents in treatment of cancer and diabetes. Various routes are available for the delivery of proteins and peptides such as oral route, transdermal route, pulmonary route, parenteral route, ocular route, nasal route, buccal route. However physicochemical properties of protein and peptides make them challenging for exogenous administration, especially in oral administration. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 44–59 Read article
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Utilization of the Sibininto treat the DMBA Induced Hepatotoxicity and Free-Radical Damage in Norwegian Rat, Rattus norvegicus (L).
Abstract: DMBA is abbreviated form of the 7,12-Dimethylbenz[a]anthracene. It is working as immuno-suppressor. It also serves as a tumor initiator. It allows for a greatly accelerated rate of growth of tumor and making many cancer studies possible. The plant, Silybum marianum (L) yields pharmacologically active compound named as silbinin. The silbinin deserve documented antioxidant activity. The purpose of this study was to assess this silbinin for protective influence in DMBA induced …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 11, Issue 1, 2020 · pp. 26–36 Read article
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A Review on Citrullus lanatus
Abstract: Citrullus lanatus is an herbaceous climbing plant and belongs to Cucurbitaceae family. It is commonly known as watermelon. It is grown in a variety of temperatures around the world. Economically it is growing very well in the word. The fruit is high in the antioxidants, lycopene and carotenoids. It helps to neutralise free radicals in our body. Watermelon seeds are high in vitamins B, protein, minerals and phytochemicals, among other …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 10, Issue 3, 2021 · pp. 12–15 Read article
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Phytochemical Analysis of Organic Compounds as an Indicator of Metal Uptake in Selected Plants
Abstract: Plants contain a number of potential chelating agents such as amino acids, organic acids, peptides, and proteins, etc. These chelating compounds are very important for the physiological processes in plants. In addition, these ligands are found in both hyperaccumulator and non-hyperaccumulator plants and play a vital role in metal uptake from contaminated soil. Many organic compounds have been found to bind and accumulate trace and toxic metals in hyperaccumulating plants. …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 3, 2020 · pp. 8–12 Read article
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Hematological and Biochemical Changes in the Freshwater Fish, Pseudetroplus Maculatus Exposed to Sublethal Concentrations of Chlorpyrifos
Abstract: Sublethal effects of chlorpyrifos on hematological and biochemical parameters were assessed in the freshwater fish, Pseudetroplus maculatus. Fish were exposed to chlorpyrifos at two sublethal concentrations, 0.661 µg/L (one-tenth of LC50—96 h) and 1.32 µg/L (one-fifth of LC50—96 h), for 15 and 30 days maintaining the control group. Blood collected from the control and treated groups were used for analyzing the hematological and biochemical parameters. Chlorpyrifos exposure significantly (P<.05) decreased …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 108–116 Read article
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Effects of Germination on the Bioactive Compounds and the Flour Physicochemical Properties of Sorghum Grains
Abstract: Sorghum, being used as a staple food with many kinds of bioactive compounds, is one of the four types of used cereal around the world. Sorghum is also an important raw material for the food industry, such as a brewing material. Germination can lead to a change of bioactive compounds, and then change the biological activities and flour physicochemical properties of sorghum grains. This review aims to analyze and summarize …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 12, Issue 1, 2024 · pp. 15–25 Read article
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The Effect of L-Valine on the Growth and Characterization of Lithium Sulphate Monohydrate Single Crystals
Abstract: Pure and amino acid doped good quality single crystals of Lithium Sulphate Monohydrate (LSM) were grown by slow evaporation solution growth technique at room temperature using water as solvent. The effect of amino acid (L-valine) dopant on the growth and characterization of LSM single crystal was investigated. Single-crystal X-ray diffractometer was utilized to find the unit cell parameters for pure and L-valine doped LSM crystals. The powder X-ray diffraction pattern …
Published in Research & Reviews : Journal of Physics · Vol. 8, Issue 1, 2019 · pp. 92–103 Read article
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Hematobiochemical Alteration in Naturally Infected Cattle with Fasciola under Tropical Region
Abstract: Fascioliasis is among one of the emerging and re-emerging disease which has zoonotic importance and spread by feco-oral route. The migrating fluke causes extensive liver damage results in economic burden to the animal farmer. In present investigation 20 cattle were used to evaluate the hemato-biochemical alteration in naturally acquired fasciola infection and without other diseases. Decreased Hemoglobin, Packed cell volume (PCV), Red blood cells (RBC) count whereas; an elevated level …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 1, 2015 · pp. 20–23 Read article
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Haemato-Biochemical Changes in Staphylococcal Species Induced Mastitis in Mouse Model
Abstract: In this study, haemato-biochemical changes in mouse mastitis by inoculating Staphylococcus epidermidis, S. chromogenes, S. haemolyticus and S. Aureus isolated from bovine milk was studied. Blood was collected by intracardiac route at 6, 12, 24, 48, 72 and 96 h. Haematological changes noticed were: white blood cells (WBC) decreased in S. haemolyticus and S. chromogenes at 48 h; S. haemolyticus and S. aureus at 96 h. S. haemolyticus showed increased …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 3, 2015 · pp. 8–14 Read article
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Ab Initio and Density Functional Theory Studies on D-Serine
Abstract: The Hartee-Fock and density functional method (B3LYP) with 6–311++G (d, p) basis set were employed to study the structural and spectroscopic properties of amino acid D-serine in ground state. The structural and vibrational parameters of amino acid D-serine were obtained using optimised conformer. Using Vibrational Energy Distribution Analysis (VEDA) 4 program and theoretically obtained FTIR and FT-Raman data complete assignment of vibrations and analysis of fundamental modes of the compound …
Published in Research & Reviews : Journal of Physics · Vol. 9, Issue 3, 2020 · pp. 29–45 Read article
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In Silico Study on Estrogens Receptor Modulators as Anti-cancer Agents
Abstract: The clinical selective estrogen receptor modulator tamoxifen is most commonly used drug for the treatment of estrogen positive breast cancer and has been preventing lives worldwide. The pioneering drug; tamoxifen used in both treatment and prevention of estrogen positive breast cancer and also addressing new research for selective estrogen receptor modulators (SERMs). Based on these for current study 20 tamoxifen derivatives has been designed for in silico study. For the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 41–54 Read article
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Analysis of Docking Study on Protein Neprilysin (Neutral Endopeptidase) Inhibition for Anti-aging Treatment by Aloe Emodin and Aloe Emodin Carbonyl Derivative
Abstract: Attempts were made to perform comparative docking study of Aloe emodin and its derivative on Neprilysin (PDB code: 1R1J) by using VLife MDS software to ascertain the activity of both. From all the interactions (Hydrogen bond and vander waals) it was observed that, the common amino acids which interacts with the common ligand were ASN542A, ALA543A, ARG102A, ASN542A, VAL580A. The result showed that the AEC (–1790.15 KCal) showed high total …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 3, 2014 · pp. 6–11 Read article
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Conventional and Molecular Approaches for Development of Quality Protein Maize
Abstract: Maize is a nutritionally poor protein quality crop because of deficient in essential amino acid lysine and tryptophan. Genetic improvement of balanced amino acid profile by application of plant breeding is most viable and sustainable strategies against battling malnutrition opaque-2 mutant is associated with high lysine and tryptophan content and it has widely used by breeder for development of quality protein maize. Adverse effect of opaque-2 genotypes is further improved …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 1, Issue 3, 2014 · pp. 12–14 Read article
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In Silico Study of Histone Deacetylase Inhibitor as Anticancer Agents
Abstract: The clinical selective histone deacetylase inhibitor vorinostat is most commonly used for the treatment of lymphoma and solid tumor and has been preventing lives worldwide. Vorinostat is used in both treatment and prevention of lymphoma and other tumors. Based on these for current study some vorinostat derivatives with thiadiazole moiety containing derivatives have been designed for in silico study. For present work, the already selected study was against histone human …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 6–23 Read article
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SGOT (Serum Glutamic Oxaloacetic Transaminase)—Its Role (A Review Article)
Abstract: Aspartate transaminase (AST) is an important liver enzyme which catalyses reversible transfer of an alpha amino group between aspartate and glutamate. It has an important role in amino acid metabolism. AST is predominantly found in the liver, skeletal muscle, kidneys, brain and red blood cells. AST is measured as a part of diagnostic liver function test, but AST reflects pathology in organs other than liver. Elevation in AST is found …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
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A Comprehensive Review on Chitosan Anticancer Property
Abstract: Chitosan, a hydrophilic, natural amino polysaccharide derived from chitin on alkaline de-acetylation. Chitosan is a nontoxic, biocompatible, antibacterial and biodegradable polymer. The biological activities of chitosan are mainly depending on the water solubility nature and also the solubility in other solvents. The primary amino group present in the chitosan is the key functional groups which is mainly responsible for its bioactivities. The biological activities of antimicrobial, antioxidant and anticancer properties …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 1–7 Read article
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Domino Reaction for the Synthesis of Nitroolefin Heterocyclic Compound Via Thiazole Formation Followed by Claisen Rearrangement
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into Claisen rearrangement. These substances, which include benzothiazole moiety, are very biologically reactive substances. This novel nitro derivative of 2-((E)-2-nitro-3-phenylallyloxy)-3-ethoxybenzaldehyde was simply treated with mole percentage of 2-(2-(2-aminophenyl) disulfanyl) benzenamine in melt reactive condition. Hence this novel 2-(benzo[d]thiazol-2-yl)-6-ethoxy-4-((E)-2-nitro-3-phenylallyl)phenol core unit compounds was very intrusting and new opportunities for the preparation of closely related to the different [3,3] sigmatropic rearrangements related …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 4, 2023 · pp. 18–22 Read article