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402 articles for “Overview”
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape
Abstract: Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of cannabinoids as nutritional supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 48–53 Read article
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A Review on The Role of Nanoparticles in Modifying Mg Alloys and Composites
Abstract: Reviewing and assessing magnesium's uses in the automobile sector, which have the potential to greatly improve fuel efficiency and environmental preservation, is the goal of this study. The report provides an overview of magnesium alloys' present benefits, drawbacks, technological obstacles, and future prospects in the automobile sector. The development of magnesium matrix composites has advanced to a new level thanks to the magnesium matrix nanocomposites' exceptional mechanical qualities. Dispersing nanoparticles …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 1, 2024 · pp. 24–32 Read article
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Arabidopsis thaliana. (L.) Heynh Multifunctional Sensor Proteins and Signaling Networks Plant Photoreceptors
Abstract: Light is a crucial environmental cue for the growth and development of plants as well as the production of photosynthetic energy. In order to recognize and process information from incoming light, plants employ sophisticated mechanisms. With the model plant Arabidopsis thaliana, five different types of photoreceptors have been found. (L.) Heynh Photoreceptors play a specialized and/or recurring role in fine-tuning many aspects of the plant's life cycle. Unlike mobile animals, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 08–24 Read article
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Ligand Based Drug Virtual Screening in Computer Aided Drug Design: A Review
Abstract: Computer-Aided Drug Design (CADD) has revolutionized the drug discovery process by providing efficient and cost-effective methods for identifying potential drug candidates. Within CADD, ligandbased virtual screening techniques play a pivotal role in the early stages of drug discovery. This review provides a comprehensive overview of ligand-based drug virtual screening, focusing on its principles, applications, challenges, and future directions. Fundamentals of ligand-based virtual screening, including pharmacophore-based methods, similarity searching, and machine …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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Comparative Evaluation of Fixed-Point Theorems Investigating Differences Among Conditions in Metric Spaces
Abstract: This paper provides a concise overview of metric spaces, their fundamental properties, and the idea of continuity as it pertains to these spaces, drawing parallels to uniform continuity and convergence. Also included is a review of previous research on metric space, its generalization, and practical outcomes from studies that utilized these spaces in various applications. We introduce a fixed point theorem for mixed monotone mappings in partially ordered metric spaces, …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 1, 2024 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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Innovative Solar Energy Applications in Agriculture and Water Management
Abstract: Considering solar energy technologies have the potential to address issues with energy sustainability and water resources, their integration in agricultural and water management has received a lot of attention. This paper offers a thorough analysis of creative uses of solar energy in different fields, emphasizing developments in technology, advantages, difficulties, and potential applications. sun photovoltaics (PV), concentrated sun power (CSP), solar desalination technologies, and solar water pumping systems are all …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 1, 2024 · pp. 8–13 Read article
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Enhancing Human Welfare In The Gig Economy: A Comprehensive Exploration Of Health And Safety Challenges
Abstract: This abstract provides a comprehensive overview of the health and safety challenges facing gig workers in the expanding gig economy. It highlights the diverse range of risks gig workers encounter, from physical hazards to psychological stressors, exacerbated by the absence of traditional employer-employee relationships. Despite these challenges, the abstract underscores the potential for innovative solutions, such as technological advancements and collaborative efforts among stakeholders, to improve worker well-being. By emphasizing …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 70–77 Read article
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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Advancement and Limitations of Raman Spectroscopy: A Review
Abstract: The present review provided an overview of advances and limitations in Raman spectroscopy— a powerful analytical tool widely used across scientific disciplines. Instrumental advances, including the development of lasers, detectors, and optics, have increased the scope of Raman spectroscopy. These advances have expanded its applications in fields such as information science and biology. The integration of Raman spectroscopy with additional technologies such as microscopy and artificial intelligence further expands analytical …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 85–97 Read article
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Advancements in Polymer-Based Sensors and Actuators for Structural Health Monitoring in Aerospace: A Comprehensive Review of Emerging Trends
Abstract: Structural health monitoring (SHM) has emerged as a critical aspect of aerospace engineering, aiming to ensure the safety and reliability of aircraft structures throughout their operational lifespan. In aerospace engineering, structural health monitoring is one of the most important aspects of aerospace engineering. It aims to ensure that aircraft structures are safe and reliable over their entire service life. Polymer-based actuators and sensors have attracted a lot of attention because …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 173–193 Read article
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Effectiveness of Structured Teaching on Immunization Knowledge and Attitude Among Mothers of Children Under-5 years of Age at Bal Mahila Chikitsalaya, Lucknow
Abstract: This section offers a thorough overview of the study's background, explaining the significance of vaccination, the variables affecting vaccination coverage, the role mothers play in the decision-making process regarding vaccinations, and the necessity of focused interventions to improve immunization uptake among children under five. As a fundamental component of preventive healthcare, immunization shields both individuals and communities from a variety of infectious diseases. In order to comprehensively assess changes in …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 5–22 Read article
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Emerging Photochemical Techniques in Green Chemistry
Abstract: Creating environmentally friendly and sustainable chemical processes is one of the main objectives of green chemistry. A viable strategy for accomplishing this goal is the use of light to trigger chemical reactions in emerging photochemical techniques. An overview of current developments in photochemical techniques that support green chemistry is given in this abstract. Key innovations include the use of visible light photocatalysis, which offers a sustainable alternative to traditional high-energy …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 39–45 Read article
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Reaching Conditions for Discrete-time Sliding Mode Control: Analysis and Design
Abstract: Sliding mode control (SMC) is a robust control method widely used in engineering due to its ability to handle uncertainties and disturbances effectively. In discrete-time sliding mode control (DSMC), system trajectories are constrained to sliding surfaces in the state space, leading to improved performance and stability. This paper provides an overview of DSMC, focusing on its applications, advantages, and limitations. It discusses the use of DSMC in various engineering fields …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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Innovative Approaches to Fake Product Detection: Blockchain and QR Code Synergy
Abstract: For consumers, corporations, and regulatory agencies, the worldwide market's rise of counterfeit goods presents serious issues. Maintaining consumer confidence, guaranteeing product safety, and preserving brand reputation all depend on the ability to identify counterfeit goods. An overview of the different approaches and difficulties associated with spotting counterfeit goods is given in this abstract. First off, the ability to identify sophisticated counterfeit goods is limited by the use of conventional techniques …
Published in International Journal of Radio Frequency Innovations · Vol. 2, Issue 1, 2024 · pp. 21–27 Read article