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626 articles for “Human epidermal growth factor receptors (HER-2)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Emotion Recognition from Electroencephalogram Signal and Eye Movement Based on Deep Learning
Abstract: Emotion recognition from electroencephalogram (EEG) signals has gained significant attention due to its potential in human- computer interaction (HCI), mental health monitoring, and personalized content delivery. This paper presents the use of Convolutional neural networks (CNNs) to classify emotions such as happiness, sadness, fear, neutral, and disgust by leveraging a fusion of EEG signals and eye movements data. Compared to conventional methods of emotion detection, such as those that rely …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 8–15 Read article
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Synthesis of A Supercapacitor Based on Nanomaterials
Abstract: Demand for various energy storage technologies in electronic and electrical devices continuously goes on increasing. In that context, objective of this research work is to develop and test an electrode of a energy storage module (supercapacitor) using nickel hydroxide and carbon-based nanocomposite materials. Electrochemical performance of electrode is enhanced by optimizing synthesis parameters and designing the electrochemical cell. Conventional and all solid-state supercapacitors are developed with notable electrochemical performance. Pure …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 24–39 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Molecular Docking Evaluation of Cedrus deodara Secondary Metabolites as a Potent Anti-ovarian Cancer Agent
Abstract: Objective: According to the statistics for the year 2022 it was seen that cancer total cases is 14,61,427. After breast cancer, ovarian cancer is the second most frequent cancer among women. The estrogen receptor (PDB ID: 1X7E), progesterone receptor (PDB ID: 1A28), and Phosphoinositide 3-kinases (PDB ID: 4FJY) can be considered as target protein for ovarian cancer. The plant Cedrus deodara and its phytochemicals were chosen in this study to …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 77–93 Read article
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Implementation of Value Management for the Project Success
Abstract: Value management plays an important role in the quality, cost, and functionality of any construction project. The article examines the various applications of value management by examining the methods and techniques in the construction industry. This article examines the various factors involved in the strategies to increase the value of the project and the factors affecting project success. The analysis of the factors was listed according to the priority matrix, …
Published in International Journal of Architectural Design and Planning Read article
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Assessment of Knowledge and Estimated Burden of Life Style Diseases in a Rural Community
Abstract: Although rapid human evolution has brought about advancement, it has also caused several lifestyle ailments. People’s daily routines have drastically changed as a result of emerging technologies, and it paved the way for numerous life style disorders. According to reports, lifestyle diseases are a major cause of increased mortality globally. Our study highlights the prevalence of life style diseases in the rural community and the need for early identification and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article
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Effect of Energy/Protein Ratio and Strain on Performance, Nutrient Digestibility and Serum Biochemical Indices of Exotic and Locally Adapted Turkey
Abstract: This study investigated the response of locally adapted and exotic turkeys raised under the same environmental conditions to diets with varying energy/protein ratio. One hundred and fourty-four (144) four-week old poults of each strain of turkey were randomly selected and assigned to six different diets in a 2 x 2 x 3 factorial arrangement. Each treatment diet were replicated twice with twelve (12) birds per replicate. Diets formulated with 28 …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 37–45 Read article
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Clinical Profile of Dengue Patients who had a Prior Infection with the Covid 19 Virus in a Tertiary Care Centre
Abstract: This cross-sectional analytical study conducted in a tertiary care center aims to investigate the clinical profile of Dengue virus-infected patients with a prior history of COVID-19 within the last three years. Dengue, a prevalent tropical disease, ranges from mild fever to severe conditions like hemorrhagic fever and shock syndrome. The study utilizes the World Health Organization's 2009 classification for Dengue and delineates the febrile, critical, and recovery phases of infection. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 34–38 Read article
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Crack Propagation Analysis in Metallic Alloys: A Comparative Study of Traditional and Advanced Materials
Abstract: A vital component of materials science and engineering, crack propagation analysis is essential to determining the structural integrity and dependability of materials. Designing safe and long-lasting structures for a variety of sectors required an understanding of how cracks begin, spread, and interact with a material's microstructure. To guarantee the performance, safety, and dependability of materials in a variety of applications, crack propagation analysis is essential. It offers insightful information about …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 33–41 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Applications of AI: Does it Impact Emissions of Carbon?
Abstract: Several countries, including India, have vowed to achieve net-zero emissions by the middle of the century, in line with the Paris Agreement's goals. India, as one of the world's largest and fastest-growing economies and the third-largest carbon emitter, has set lofty goals in its climate change plan. By 2030, India intends to attain carbon peaking, which represents the top of its carbon emissions before beginning a slow drop. Furthermore, the …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 27–31 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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Diabetic Risk Prediction Using Machine Learning
Abstract: The global prevalence of Type 2 diabetes has risen dramatically in recent years, posing a serious public health risk. Long-term risk prediction is an important technique for evaluating who is most likely to develop type 2 diabetes. Early detection and response can lead to better management and prevention of diabetes complications. Developing a user-friendly Windows program for long-term Type 2 diabetes risk prediction could revolutionize preventive healthcare due to technological …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 1, 2024 · pp. 11–17 Read article
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Pedagogical Innovations and Student Voices: A Longitudinal Examination of Engagement in Elementary Schools
Abstract: From 2023 to 2024, this mixed-approaches longitudinal study follows students of varying ages to see how characteristics related to emotional and social development, curriculum flexibility, and innovative teaching methods affect their engagement and performance in the classroom. Educators and students are followed for one year in this study to see how educational approaches change and impact students' learning. For this study, researchers conducted a one-time survey of a sizable group …
Published in International Journal of Education Sciences · Vol. 1, Issue 2, 2024 · pp. 44–55 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Mind-Machine Synergy: The Evolution and Future of Brain-Computer Interfaces
Abstract: Brain-Computer Interfaces (BCIs) represent a transformative technology that enables the direct communication between the human brain and external devices, bypassing the traditional output mechanisms, such as speech or physical movement. BCIs hold the potential to revolutionize fields, such as healthcare, neuroscience, and human-computer interaction by providing new ways to restore lost functions, enhance cognitive abilities, enable seamless communication, and create novel user experiences across various platforms and environments. This article …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 19–31 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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Evaluation of New Fungicides for the Management of Mango Anthracnose Disease Caused by Colletotrichum Gloeosporioides
Abstract: A field experiment was conducted at the field of Plant Pathology Division, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur-2000, Bangladesh during February to July 2024 to assessment the efficacy/effectiveness of thirty-five (35) new fungicides received from Pesticide Technical Advisory Committee (PTAC), Bangladesh with control treatment against anthracnose disease of mango. Most of the fungicides under inspection were able to control the disease successfully. This study suggests …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 1, 2026 · pp. 1–16 Read article