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470 articles for “Doses”
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Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
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Toxicology and Its Branches: A Brief Review
Abstract: Toxicology is called the science of poisons or can be defined as any substance, whose exposure can cause harm to any living body or to the environment. It can also be defined as the study of adverse effects of different chemical, biological or physical agents on living organisms and the ecosystems, including the prevention & enhancement of such adverse effects. It is concerned with all aspects of different poisons and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 2, 2024 · pp. 27–45 Read article
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Measurement of Indoor Radon Concentration in a Residential House of Surrey (BC) Canada using LR-115 type II Plastic Detector
Abstract: Indoor radon concentration activity measurement has been considered as a useful parameter in evaluation of health hazards due to radon. The major health hazard is lung cancer attributable to radon in Canada which causes 16% of total lung cancer deaths. The purpose of this study is to determine indoor radon concentration (Bq/m3) and effective annual dose (mSv/yr) in a residential building. Plastic detector LR-115 Type II has been used for …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 2, 2022 · pp. 21–29 Read article
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Toxicology 4.0: Integrating Artificial Intelligence, Big Data, Health Informatics, and Precision Analytics for Predictive Toxicity Assessment, Real-Time Toxicovigilance, and Personalized Patient Safety
Abstract: Background: Toxicology is undergoing a major transformation, increasingly described as Toxicology 4.0, driven by the integration of artificial intelligence (AI), big data analytics, health informatics, and precision analytics. Conventional toxicity testing is limited by high costs, lengthy timelines, and challenges in translating animal and low-throughput in vitro findings to humans. Aim and Objectives: To comprehensively evaluate the emerging role of Toxicology 4.0 in predictive toxicity assessment, real-time toxicovigilance, and personalized …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 Read article
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IoT-Based Smart Medicine Box with AR Holographic Caregiver and Automatic Liquid Tonic and Pill Dispensing System
Abstract: Medication management is a major challenge for elderly individuals, chronic disease patients, and users who require multiple medicines at scheduled intervals. Missed doses, incorrect quantities, and improper medication handling can reduce treatment effectiveness and create health risks. This paper proposes an IoT-Based Smart Medicine Box with an AR Holographic Caregiver and Automatic Liquid Tonic & Pill Dispensing System to provide a reliable and intelligent medication management solution. The proposed system …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 14, Issue 2, 2025 · pp. 19–24 Read article
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Dosimetric Aspects of Sodium Polystyrene Sulfonate (NaPSS)
Abstract: Thermally stimulated luminescence (TSL), electron spin resonance (ESR), Fourier transform infrared spectroscopic techniques are used to study dosimetric applications of sodium polystyrene sulfonate (NaPSS). The TSL, ESR, FTIR spectra are recorded for NaPSS-exposed different amounts of gamma radiation doses. The spectra observed under different conditions suggest that the NaPSS can be used for dosimetric applications based on the condition of linear variation of physical properties against the radiation dose.
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 4, Issue 3, 2013 · pp. 7–10 Read article
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BVM: A Promising Agent for Future HIV-1 Treatment
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} More than 20 individual and fixed-dose combinations of anti-HIV drugs are available for the treatment of human immunodeficiency virus (HIV) infection. However, owing to the development of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 1, 2011 · pp. 11–21 Read article
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
Abstract: The present study was performed in pylorus ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 42–49 Read article
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Anti-nociceptive Potential of Scurrula parasitica: An Unexploited Parasitic Plant
Abstract: Scurrula parasitica (Loranthaceae) is an herbaceous growing shrub parasitic on Dendrophthoe falcata (Loranthaceae) which is itself parasitic on Mangifera indica (Anacardiaceae). Scurrula parasitica is distributed throughout the western ghat region of Maharashtra, some parts of Uttar Karnataka and Tamil Nadu. Genus Scurrula comprising of around 91 species, however, only S. ferruginea, S. atropurpurea, S. fusca have been investigated systematically. No such pharmacological and phytochemical data are available on the plant …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 · pp. 4–8 Read article
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Evaluation of Anti-inflammatory Activity of Zornia gibbosa Span (Samyojaki)
Abstract: 93% of wild medicinal plants used for making Ayurvedic medicines in the country are endangered. Hence the usage of drugs which are common and abundantly available should be encouraged to control the extensive overuse of few classical drugs. An Ayurveda states that every drug possesses medicinal property, so it’s our prime duty to scrutinise those drugs which are abundantly available & cost-effective for their medicinal value. The herb Zornia gibbosa …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 5–8 Read article
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Analgesic Activity and Acute Toxicity Study of Zornia gibbosa Span (Samyojaki) in Mice
Abstract: The herb Zornia gibbosa Span is a member of fabaceae family and commonly known as Nellujollusoppu/Haradahacchaga in Udupi district of Karnataka. The drug is widely used in the treatment of fracture by folklore practitioners to pacify pain and inflammation. In fracture the pain is generated by multiple nociceptors presence in response to discontinuity of periosteum and endosteum during trauma. So in order to justify the folklore claims, pharmacological analysis of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 1–4 Read article
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Therapeutic Drug Monitoring (TDM): An Aspect of Clinical Pharmacology and Pharmacy Practice
Abstract: AbstractTherapeutic drug monitoring or TDM is the clinical pharmacology of measuring specific drugs at designated intervals to uphold a constant level of drug in a patient’s blood circulation, thereby optimizing individual dosage regimens. TDM becomes necessary only for the categories of drug with narrow therapeutic ranges, drugs with marked pharmacokinetic variability, medications for which target concentrations are difficult to monitor, and drugs known to cause therapeutic and adverse effects. On …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 27–34 Read article
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Evaluation of Efficacy of Hulba (Trigonellafoenumgraecum Linn.) in Rheumatoid Arthritis: A Randomized Control Trial
Abstract: The prevalence of the disease is approximately 0.5–1%. Rheumatoid arthritis has a large impact on patient’s quality of life and it has also been associated with a reduced life expectancy. Therefore, the study was conducted to evaluate the efficacy of Tukhm Hulba (Trigonellafoenumgraecum Linn.) in the management of rheumatoid arthritis. The study was carried out as a single, blind, randomized and standard controlled trial, to evaluate the efficacy of Tukhme …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 3, 2016 · pp. 27–34 Read article
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Morinda citrifolia Leaf Induced Leukemia Cells Apoptosis and Produced Synergistic Effects with Zerumbone
Abstract: Leukemia is the most common cancer among children and the 7th most common cancer worldwide. The vegetable Morinda citrifolia leaves was investigated and compared with Zerumbone (a known anti-leukemia compound) separately and in combination, for their apoptotic effects on murine myelomonocytic leukaemia cell line (WEHI-3B). Zerumbone, a sesquiterpene from Zingiber zerumbet was anti-cancer via suppressing free radical generation, inflammation, cancer cell proliferation, metastasis, anti-apoptosis, NF-κβ, Iκβα kinase activation and invasion. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 24–32 Read article
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Research and Industrial Insight: Toxicology
Abstract: Toxicology is a division of biology, chemistry, and medicine related with the study of the special effects of chemicals on breathing organisms. It also studies the injurious effects of chemical, biological and physical mediators in biological system that founds the degree of destruction in living organisms. The correlation between dose and its belongings on the exposed organism is of great importance in toxicology. A factor that inspires the chemical toxicity …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 36–40 Read article
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Removal of Lead and Zinc from Industrial Waste water by Amla leaves Nano-bioadsorbent
Abstract: In the present research work, amla leaves (Phyllanthusemblica) were used for preparing nanobioadsorbent to remove heavy metals viz. Lead (Pb) and Zinc (Zn) present in wastewater. The major advantage of using amla leaves as bioadsorbent is its easy availability, abundance, low cost, biodegradable and eco-friendly nature. Prepared bioadsorbent was characterized by infrared spectroscopy (IR), SEM and BET techniques. Variation in the experimental conditions such as pH, adsorbent dosage, stirring speed …
Published in Journal of Water Pollution & Purification Research · Vol. 9, Issue 1, 2022 · pp. 6–15 Read article
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Arsenic Removal by Using Low Cost Non-conventional (NLP, PLP, ALP) Adsorbents
Abstract: AbstractIn present study, Azadirachta indica (neem leaves), Ficus religiosa (peepal leaves), Emblica officinalis (amla leaves) used as adsorbent. Batch experiments were conducted to study the adsorption behaviour. The material was characterized by FTIR, XRD, TGA-DTA, and SEM-EDS. The extent of arsenic removal capacity was tested by the material by varying the solution parameters like adsorbent dose, adsorbate concentration and pH of the solution, contact time and temperature. The amount of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 3, 2018 · pp. 29–39 Read article
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Effect of Sulphur and Zinc on Yield Quality and Nutrient uptake of Hybrid Rice in Sodic Soil
Abstract: ABSTRACTA field experiment was conducted to study the effect of sulphur and zinc on yield, quality and nutrient uptake by hybrid rice grown in sodic soil. Application of 40 kg S ha−1 recorded significantly high grain and straw yield, protein content and sulphur uptake. Similarly, positive response of hybrid rice to zinc application was also noticed significantly up to the zinc dose @ 10 kg ha−1. Increasing doses of sulphur …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 1, Issue 2, 2012 · pp. 13–17 Read article
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Effect of Kitchen Waste Compost and Vermicompost in Combination with Chemical Fertilizer on the Production of Stem Amaranth
Abstract: The study was carried out at Horticulture Research Centre (HRC) field, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during April to June 2014 to determine the optimum dose of organic fertilizer in combination with inorganic fertilizer on yield and quality of stem amaranth. BARI Danta-1 (Laboni) was used in the study. Eight treatments were constructed with the fully matured compost for each evaluation, these were, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 8, Issue 1, 2019 · pp. 28–39 Read article
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Effect of Kitchen Waste Compost and Vermi-Compost in Combination with Chemical Fertilizer on the Production of Tomato
Abstract: An experiment was carried out to develop standard production method of winter tomato under Good Agricultural Practices (GAP) and value chain development at the farmer’s field named Mojnu Mia son of Nishan Mondal located at Char dudiagacha, Adarvita, Madarganj, Jamalpur, Bangladesh with the assistance of HELVETAS, Swiss Inter Cooperation, Bangladesh, Jamalpur during November 2015 to April 2016. BARI Tomato-14 was used in the study. Eight treatments were constructed with the …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 3, 2017 · pp. 15–24 Read article