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1680 articles for “BCS Class II/IV drugs”
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Artificial Intelligence in Drug Repurposing: A Short Impact Assessment
Abstract: Artificial intelligence (AI) in pharmaceutical repurposing has become a game-changing tool that opens new avenues for the application of new drugs that have already been approved. Traditional drug discovery is a lengthy and expensive process, whereas AI can rapidly analyze vast datasets of biological, chemical, and clinical information to predict drug-disease interactions. AI-driven techniques, such as machine learning, natural language processing, and deep learning, enable the identification of potential repurposing …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 42–45 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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Development of a Blockchain-Based System for Drug Counterfeiting and Traceability in the Pharmaceutical Supply Chain
Abstract: Counterfeit drugs present a major risk to public health and pose a substantial threat to the pharmaceutical industry, leading to severe economic losses and risking patient lives. Ensuring the safety and authenticity of the pharmaceutical supply chain is critical to addressing this issue. This study presents a novel approach for enhancing the security and authenticity of the pharmaceutical supply chain through the integration of blockchain technology, decentralized storage, and artificial …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 99–114 Read article
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Parkinson’s Disease Detection on Spiral Images Using CNN with Meta-Classifiers
Abstract: In this work, we provide a detailed method for identifying Parkinson’s Disease (PD) by integrating Convolutional Neural Network (CNN) and meta-classifiers. Through the utilization of a varied dataset consisting of handwritten spiral images, our methodology demonstrates commendable accuracy across a range of models. Specifically, our CNN model with meta-classifiers surpasses alternative approaches, achieving an impressive accuracy rate of 95.07%. By utilizing pre-established VGG16 and ResNet50 architectures as bases, the region-based …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 1, 2025 · pp. 55–66 Read article
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Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases
Abstract: Among all the Drug Delivery Systems, Snehpana (~Lipid Based Drug Delivery System) is being widely used because this facilitates uniform distribution and absorption of fat and water-soluble chemical constituents. Due to their effective size-dependent properties and challenges related to the solubility and bioavailability of water-soluble drugs, this system holds a significant advantage. Numerous studies have highlighted the potential of lipid-based formulations in managing chronic and life-threatening diseases. Shatpala ghrit (SG) …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 1–11 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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Controlled Drug Delivery of Furosemides Using Floating Tablet System
Abstract: The development of gastroretentive drug delivery systems (GRDDS) has gained interest, particularly for drugs like furosemide with narrow absorption windows in the upper gastrointestinal (GI) tract. Furosemide, a commonly used diuretic, faces challenges due to limited bioavailability and rapid elimination, requiring frequent dosing and affecting patient compliance. This review highlights the formulation and evaluation of floating furosemide tablets as an effective strategy to enhance therapeutic efficacy. Floating tablets allow prolonged …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 23–31 Read article
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Implementing Machine Learning in Data Classification
Abstract: Data classification forms an essential aspect of artificial intelligence (AI) and soft computing, helping a great deal in the transformation of raw data into knowledge that forms the basis of numerous applications, such as fraud detection, medical diagnostics, and natural language processing. This study discusses the challenges and the state of the art in data classification, as far as scalability, noise handling, and feature selection optimization are concerned. It gives …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 2, 2025 · pp. 15–22 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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An Empirical Study of Hyperparameter Impact on Deep Learning Models for Cardamom Leaf Disease Classification
Abstract: Recent advancements in deep learning models like convolutional neural networks and self- attention mechanisms have achieved great success in the field of plant disease classification. This study investigates the efficacy of two pre-trained models, ConvNeXT-Tiny and Swin Transformer-Tiny, for leaf disease classification in cardamom using a publicly available dataset constituting three categories of leaves, namely Healthy, Colletotrichum Blight and Phyllosticta Leaf Spot. The effectiveness of the models highly depends on …
Published in Current Trends in Information Technology · Vol. 15, Issue 3, 2025 · pp. 48–60 Read article
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AI in Healthcare: Drug Delivery in Tuberculosis
Abstract: Tuberculosis (TB) , mainly caused by Mycobacterium tuberculosis, remains a major global health burden, accounting for millions of new infections and deaths each year. Although progress has been made in diagnosis and treatment, the growing threat of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB makes disease control increasingly difficult. Conventional diagnostic approaches such as chest X-rays, sputum smear microscopy, and culture methods continue to play an important role, but they …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 9–17 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Fault Diagnosis of Air Compressor (AC) System using Local Mean Decomposition (LMD) and Logistic Regression (LR) Machine Learning Classifier
Abstract: This article presents a detailed and systematic procedure for performing fault diagnosis in an air compressor (AC) system by analyzing the audio signals generated during its operation. The analysis covers both normal (healthy) conditions and seven distinct types of faults, including bearing failure, flywheel malfunction, inlet valve leakage, outlet valve leakage, non-return valve failure, piston ring defect, and rider belt issues. To acquire the acoustic signals, the researchers utilized a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 416–427 Read article
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Synthesis and Spectral Characterization of Complexes Tin(II) With 4-Nitrophenol
Abstract: Tin(II)4-nitrophenoxide complexes with the formulas SnCl(OC₆H₄NO₂-4) and Sn(OC₆H₄NO₂-4)₂ were prepared through the reaction of stannous chloride (SnCl₂) with 4-nitrophenol (HOC₆H₄NO₂-4) in 1:1 and 1:2 molar ratios, respectively. The reaction was performed in tetrahydrofuran (THF) with diethylamine serving as the base. The resulting compounds were characterized through elemental analysis, determination of molecular weight, molar conductance measurements, and spectroscopic methods including IR and ¹H NMR spectroscopy. Current investigations are directed toward assessing …
Published in International Journal of Advance in Molecular Engineering · Vol. 4, Issue 1, 2026 · pp. 22–26 Read article
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Multi-Parameter Biomedical Sensor-Based Mental State Classification Using EEG And Deep Learning Techniques
Abstract: With mental health concerns becoming increasingly widespread, there is a strong need for systems that can monitor conditions like stress, anxiety, and fatigue in a continuous and non- invasive manner. This research proposes a novel multi-parameter biomedical sensing framework for mental state classification by integrating electroencephalography (EEG) signals with physiological parameters, including body temperature acquired using LM35 sensors, heart rate from pulse sensors, and blood oxygen saturation (SpO₂) measurements. The …
Published in Current Trends in Signal Processing · Vol. 16, Issue 2, 2026 Read article
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Smart Drug Delivery Using Nanorobots
Abstract: In recent years, the field of micro/nanorobot research has gained popularity. Because it can be used in targeted medication distribution, surgical procedures, disease detection, etc., it has enormous promise in medical therapy. Different from conventional medication delivery, which depends on blood flow to drug delivery to difficult-to-reach locations is made possible by the planned micro/nanorobots' ability to move independently. Micro/nanorobots were powered by either endogenous power (chemical reaction energy) or …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Hybrid Quantum-Classical Reinforcement Learning Enabled Thermal-Aware Electronic Design Automation Framework for Energy-Efficient Next-Generation VLSI Systems Applications
Abstract: Modern Very Large-Scale Integration (VLSI) systems are becoming more complicated, which has increased need for sophisticated Electronic Design Automation (EDA) frameworks that can concurrently optimise thermal behaviour, power consumption, and performance. This study proposes a Hybrid Quantum-Classical Reinforcement Learning (HQCRL) Enabled Thermal-Aware EDA Framework for next-generation energy- efficient VLSI systems. The proposed framework integrates quantum-inspired optimization techniques with classical reinforcement learning algorithms to address the challenges of placement, routing, and …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 2, 2026 Read article
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Enhancing Smart Grid Resilience Through AI-Based Fault Classification
Abstract: Traditional power grids can be developed into smart grids, and they are comprised of the latest information and communication technologies (ICTs), which are based on establishing the relationship between the conventional electricity systems along with the usage of smart meters and distributed generation. This dynamic improves energy efficiency and the integration of renewables. Well, the dynamic and reversible power injection from Distributed Energy Resources (DERs) creates substantial operational problems. These …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 10–15 Read article