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508 articles for “Anti – infective”
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Ventilator Associated Pneumonia: Prevalence of Bacteria and their Antibiogram in Tertiary Care Centre, Kota, Rajasthan, India
Abstract: Background: Mechanical ventilation is a life-saving procedure, but it is associated with a high risk of acquiring respiratory infections. Hence to prevent it and initiate empirical antimicrobial therapy, knowledge of microbial profile and their local antimicrobial sensitivity pattern are essential. The study aimed to investigate the role of endotracheal aspirate (ETA) surveillance cultures in identifying the aetiology of VAP earlier. Methods: A prospective study was carried out over a period …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 1, 2021 · pp. 30–34 Read article
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Silver Nanoparticle as Antiviral Agent and Its Uses
Abstract: Silver had been used by human thousands of years ago as various types of medicines (RasaratnaSamuccahay, Bhagbhatta). As the years passes more scientific uses of silver metals had been seen as the human civilization progresses.After the discovery of nano technology Silver is being used in a variety of ways .Nano particles exhibits less toxicity as compared to their ionic counterpart. Nowadays silver is used in various forms colloidal silver Nanoparticle …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 22, Issue 1, 2020 · pp. 28–34 Read article
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NEWEST RESEARCH ON FUNGAL MEDICATIONS
Abstract: Mycosis is a disorder brought on by mould or yeast, commonly known as a fungal infection. Although fungi (plural of fungus) can spread diseases to the mouth, throat, lungs, urinary tract, and many other regions of the body, skin and nails are the most common sites for fungal infections. You will experience various symptoms depending on the kind of fungus infection you have and where it is on your body. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 18–26 Read article
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Artificial Intelligence In Transfusion Medicine And In Our Mission To “BEAT- COVID”
Abstract: The key objectives of this manuscript are: 1] Demystifying the buzzword of Artificial Intelligence [AI] and comparing neuronal networkings similarity of machines with some mammals; 2] Exploring, from outside sources, the breath of some computerized procedural data generated in laboratory and clinical areas of medicine, by robotic tools in the cutting age of transfusion medicine; 3] Expressing views on the variabilities of covid- associated long lasting microcirculatory disseminated pathogenic autoimmune …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 7, Issue 3, 2020 · pp. 10–21 Read article
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Antibiotic prescribing patterns in paediatrics at a tertiary care hospital in Mansa, Zambia
Abstract: ABSTRACTBackground: Antibiotics are one of the most widely used groups of drugs. Irrational and uncontrolled use of these agents both in developing and developed countries has resulted in an evolution of resistant strains in addition to poor health outcome. Aim: The aim of this study was to evaluate the prescribing pattern of antibiotics for paediatrics using WHO prescribing indicators.Methods: A cross sectional Retrospective study was conducted at Mansa general hospital, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 62–71 Read article
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Prolonged Antibiotic Use and Reproductive Challenges in Dairy Cows: Implications for Ovarian, Uterine, and Overall Reproductive Health
Abstract: The widespread use of antibiotics in dairy farming has raised concerns regarding its potential impact on reproductive performance. Prolonged antibiotic administration can disrupt endocrine regulation, alter ovarian function, impair uterine health, and compromise overall fertility in dairy cows. This review explores the multifaceted consequences of antibiotic exposure on reproductive physiology, highlighting its effects on hormonal balance, follicular dynamics, uterine microbiota, and embryo viability. Antibiotics may induce hormonal imbalances that interfere …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 22–40 Read article
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Dermatophytoses: Taxonomy, Pathogenesis, Diagnosis, Resistance, and Management.
Abstract: Dermatophytes, belonging to the family Arthrodermataceae, are keratinophilic fungi responsible for superficial mycoses. Dermatophytoses affect the skin, hair, and nails globally. Over the last few years, dermatophytic infections have seen a sharp rise in India, with the main causative agent being antifungal-resistant Trichophyton mentagrophytes genotype VIII. This review provides a detailed overview of dermatophytoses, including taxonomy, pathogenesis, epidemiology, diagnosis, and treatment. Dermatophytes belong to the kingdom Fungi, family Arthrodermataceae, with …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 28–37 Read article
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In Silico Molecular Docking Studies of Phytocompounds from Melissa officinalis Against MPXV Poxin Target
Abstract: Objectives: This study aimed to evaluate the inhibitory potential of phytocompounds of Melissa officinalis against the MPXV poxin protein target, a key virulence factor in monkeypox infection. Methods: Molecular docking performed using PyRx, a virtual screening software, was conducted to predict the binding affinities of the compounds to MPXV poxin. Prior to docking, the compounds were subjected to comprehensive analysis, including Lipinski's rule of five, evaluation of physicochemical properties, pharmacological …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 25–38 Read article
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A Comparison of Rapid Card Test with Enzyme-Linked Immunosorbent Assay for the Detection of Hepatitis B Surface Antigen [HBsAg] in Tertiary Care Hospital
Abstract: Introduction: Hepatitis B virus (HBV) infection is one of the leading causes of death worldwide. The most important marker for HBV infection is HBsAg. In case of diagnosis of infectious disease, discordant results may have serious consequences among the patients as it causes unnecessary mental stress and tension. For proper diagnosis of infection as well as disease management and prevention, identification of appropriate test kit is necessary. Aims and Objective: …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 27–31 Read article
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Antimicrobial Susceptibility Profile of Airborne Bacteria and Fungi at Owena Market, Osun State, Nigeria
Abstract: Environmental conditions and human activities influence the ubiquity and diversity of microorganisms in the atmosphere thereby acquiring the ability to resist antibiotics which poses serious public threat. Airborne bacteria and fungi isolated using settling plate method from three different points (where kolanuts, meat and onions are sold) at Owena Market, Osun state, Nigeria were assayed for antimicrobial susceptibility using disc diffusion. The microorganisms were identified as Staphylococcus aureus, Bacillus subtilis, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 2, 2017 · pp. 12–16 Read article
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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Worldwide Threatening Sign-Antibiotic Resistance its Prevention and Control
Abstract: Antimicrobial agents play a key role in controlling and curing infectious diseases in different fields of medical. Transitorily after the sighting of various groups of antibiotics and the use of antibiotics has increased globally, the challenge of antibiotic resistance has come into the picture worldwide on a very serious note. Based on the mechanism of action of antibiotics they are broadly classified as: Bactericidal and bacteriostatic. Antibiotics are a very …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 34–38 Read article
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Phytoconstituents of Eclipta alba Targeting Various Protein Sequences of Coronavirus: An Insilco Approach
Abstract: Abstract Background: The major disaster in the 21st century is the Novel-Coronavirus 2019 (nCoV or COVID-19) and Severe Acute Respiratory Syndrome-related coronavirus (SARS-CoV). In the year 2019, a new strain of coronavirus (CoV) was recognized in Wuhan city of China. In the current scenario there is no specific drug or therapy is for treating COVID-19 infections which is turning to be extremely fatal. Based on the literature survey for natural …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 28–51 Read article
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A Review on Aegle Marmelos: A Potential Medicinal Tree
Abstract: Bael, Aegle marmelos (Linn.) Correa ex Roxb., A tree of Indian origin has been known since prehistoric times. It has the significance of a great myth to Hindus. The use of daily life has great nutrition, environment and commercial significance. It has long been used in traditional medicine to treat constipation, diarrhea, diarrhea, peptic ulcer and respiratory infections. Essential therapeutic properties of baelareantidiabetic, antimicrobial, anti-inflammatory, antipyretic, analgesic, cardioprotective, antispermatogenic, anticancer …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 5–12 Read article
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Biofilm Forming and Antimicrobial Susceptibility of Clinical Isolates of Staphylococcus Species
Abstract: Staphylococcus species are the most frequent causes of infection and infections on indwelling medical devices, which characteristically involve biofilms. This study observes the biofilm forming abilities and to analyze antimicrobial susceptibility pattern of clinical isolates of Staphylococcus species were found to be biofilm producers by microtitter plate assay method. And to evaluate the antibiofilm property of Moringa oleifera an Indian medicinal plant, known to possess antimicrobial activity. The results demonstrate …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 2, 2015 · pp. 1–4 Read article
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Revolutionizing Vaccine Development:The Transformative Role of Bioinformatics in Designing Next-Generation Immunotherapies
Abstract: Vaccines have long been central to the prevention and control of infectious diseases, dramatically reducing morbidity and mortality worldwide. In the modern era, the integration of bioinformatics has revolutionized vaccine development by enabling rapid, precise, and cost-effective identification of potential vaccine targets. This seminar explores the multifaceted applications of bioinformatics in vaccinology, including antigen discovery, epitope prediction, structural modeling, molecular docking, and immunoinformatics-driven vaccine design. Special emphasis is placed on …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 19–33 Read article
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Epitope-Based Peptide Vaccine Design Against Nuclear Protein EBNA3C of Epstein-Barr Virus: An Approach to Treat Multiple Sclerosis
Abstract: Almost 95% of the world’s population is affected by the Epstein-Barr virus (EBV); it is an oncogenic virus of herpes virus family. The nuclear protein Epstein-Barr nuclear antigens (EBNA)-3C of EBV are related to multiple sclerosis (MS) which is an inflammatory disease of the nervous system. Regardless of multiple occurrences of infections due to EBV and shortage of licensed antiviral drugs, there is not much advancement on vaccine designed for …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 62–72 Read article
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It is Not an Aberration, It is Fragment of our Correlated Viral Age
Abstract: Corona viruses are a cluster of allied contamination of germs that is originated in creatures and birds. In humanoid, corona viruses are rooted through respiratory, wheezing zone which infects the body and fluctuates from lightest to life threatening stage. The incurable classification of diseases are Severe acute respiratory syndrome-related corona virus (SARS), Middle East respiratory syndrome-related corona virus (MERS) and COVID-19. Till now, this contaminated germ disease does not have …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 2, 2021 · pp. 43–49 Read article
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Extracellular Biosynthesis of Silver Nanoparticles using the Fungus Pleurotus ostreatus and their Antibacterial Activity
Abstract: In the present study, an eco-friendly process for the synthesis of nanomaterials using a fungus (Pleurotus ostreatus) has been attempted. The fungus supernatant of seed culture was used for the biosynthesis of silver nanoparticles. The aqueous silver ions were reduced to silver metal nanoparticles when treated with the fungal supernatant. After 72h of treatment, silver nanoparticles were obtained. These silver nanoparticles were characterized by UV–Vis spectroscopy, scanning electron microscopy (SEM), …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 2, Issue 2, 2012 · pp. 28–38 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article