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563 articles for “ADMET lab 2.0” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Tamil Migration to Colonial Malay and Burma from 1880-1920: Analysing the Acculturation Process through the Lens of Fashion
Abstract: This paper seeks to understand the cultural repercussions of colonial labour migration, which emerged as one of the key characteristics of the 19th century as European nations set up colonies in parts of Africa, Latin America, and South and Southeast Asia. The ‘coolie’ market consisted of indentured labourers and slaves and allowed the colonial rulers to supplement labour in new colonies. As the labourers migrated to new lands, they carried …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 19–24 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Exploring Moth Diversity in the Ecosystem of Mangalore University Campus, Karnataka
Abstract: The moth is one of the genera of insects of the order Lepidoptera, where butterflies share the same genus. They have nocturnal habits and a high attraction to light. Moths have various sizes, shapes, and colors, with many having duller colors. A study was conducted on the diversity of moth species in Mangalore University campus, Mangalore, Karnataka, for eight months (August 2006 to March 2007). We recorded 39 moths belonging …
Published in International Journal of Insects · Vol. 1, Issue 1, 2024 · pp. 22–29 Read article
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Exploring the Therapeutic Potential of Grapeseed Phytoconstituent Through Molecular Docking Analysis for Multiple System Atrophy Treatment
Abstract: Objective: Alpha-synuclein (α-Syn) aggregates are a common neurodegenerative disorder associated with Parkinson’s disease and multiple system atrophy (MSA). As a fruit that is extensively grown, grapes have several pharmacological advantages when it comes to reducing oxidative stress. Research has indicated that grape seed phytoconstituents have a major effect on α-Syn. The objective of this study is to inquire into the pharmacological characteristics and potential therapeutic applications of grape seed derivatives …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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A Study to Evaluate the Impact of Nurse-led Intervention on Competency Level Regarding Care of Patients on Mechanical Ventilators Among ICU Nurses Working in Selected ICUs at Pt. Bd Sharma PGIMS Rohtak
Abstract: Introduction: The nurse caring for mechanically ventilated patients must be skilled and possess a deep understanding, along with specialized knowledge, of mechanical ventilators (MV). This study is intended to evaluate the impact of nurse-led intervention on competency levels regarding the care of patients on MV among ICU nurses. Objective: To assess the pre- and post-test knowledge, practices, and attitudes of ICU nurses, evaluate the effectiveness of nurse-led interventions on the …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 59–94 Read article
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Assessment of Physico-Chemical and Microbial Analyses of Hand Dug Wells in Makeni Town, Sierra Leone
Abstract: The various water samples were analysed for residual chlorine, ammonia, fluoride, nitrate, sulphite, lead, arsenic, chromium, and bicarbonate levels from January to August 2024. The bacteria contamination was investigated to determine the safety of the water for the consumption of human. The temperatures across the four wells ranged 27.3oC to 30.0oC, with and average values ranging from 27.94oC to 29.15oC. pH values were within the WHO recommended guidelines range of …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 2, 2024 · pp. 01–13 Read article
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Diglycidyl Ether of Bisphenol A (DGEBA) Based Epoxy Sizing Agent Induces Surface Polarity in Carbon Fibers†
Abstract: Determination of the chemical structure and composition of the sizing agent is a challenge as its concentration is low, varying in the range from ~0.5 wt.% (for polyacrylonitrile, PAN, based carbon fibers) to ~1 wt.% (for pitch-based carbon fibers). Moreover, such a piece of knowledge is vital for designing compatible polymer matrices to prepare CFRPs for diverse applications. As a result, the sizing layer that is coated on the carbon …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 24–34 Read article
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Frequency of Failed Spinal Anesthesia and Associated Factors in Cesarean Section at Mardan Medical Complex, Mardan, KP, Pakistan
Abstract: Objective: Spinal anesthesia is the preferred choice of anesthesia for parturients having cesarean sections. Despite the high percentage of success in providing acceptable surgical anesthesia, failure of spinal anesthesia has been reported. This study aims to determine the frequency and associated factors related to failed spinal anesthesia during cesarean sections in pregnant women. Methodology: This descriptive cross-sectional study included 149 pregnant women and was conducted at Mardan Medical Complex (MMC) …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Role of Organizational Culture in Mediating AI-Induced Social Alienation: A Meta-Analysis
Abstract: The fast adoption of artificial intelligence (AI) in the workplace has raised worries about its influence on employee well-being, particularly social alienation. Social alienation is characterised by feelings of detachment and estrangement at work. It can harm job satisfaction, staff engagement, and organisational performance. Existing literature suggests that organizational culture is crucial in shaping employee experiences with AI technologies. This meta-analysis investigates how organizational culture mediates the relationship between AI …
Published in Recent Trends in Social Studies · Vol. 2, Issue 1, 2025 · pp. 28–33 Read article
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A Sensitive SPE-ECD-GLC Procedure for Analyzing Simazine Quantitatively in Food Products
Abstract: Short and simple solid-phase extraction (SPE) method interfacing and hyphenating gas liquid chromatographic-electron capture detection (GLC-ECD) method has been developed for the qualification and quantification of simazine in some daily used agro products. United States Pharmacopeia G-42 gas chromatography stationary phase with ZB-35a, HTb Inferno-cZ (Zebron, Za) capillary column with an enlarged and extended temperature range of –60° to 400°C and electron capture detector was selected correlating some chemical, physical …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 20–27 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Comparative Analysis of Kinetic Models for Simulation of Biogas Production from Cow Dung and Fruit Waste via Anaerobic Digestion
Abstract: This study investigates the optimization of biogas and biofertilizer production from cow dung and fruit waste through anaerobic digestion, utilizing various microbial growth kinetic models. Simulations were conducted using the Monod, Moser, Contois, and Tessier models to predict biogas yield and assess model accuracy. Results indicated that the Tessier model provided the closest fit to experimental data, with a biogas yield of 0.45 m³/kg VS, while the Monod model overestimated …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 47–63 Read article
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Trend Analysis of Long-Term Rainfall Data for Monsoon Season of Kharun Catchment
Abstract: This research paper investigates the trends in monsoon season rainfall over a 31-year period (1990–2021) using the non-parametric Mann–Kendall test. A range of statistical methods were utilized to analyze the rainfall data, providing valuable insights into its temporal patterns and trends. The correlation coefficient, measured by Kendall's Tau, exhibited a minimal positive correlation of 0.004 between years and their corresponding rainfall, quantities. This implies a slight tendency for increased rainfall …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 1, 2025 · pp. 12–17 Read article
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Effect of 4-Week Protocol of Kegel Exercise on Pelvic Floor Strength on a Patient with Ovarian Endometriosis—A Case Report
Abstract: Purpose: The purpose of this case study was to describe the effects of Kegel exercise in a 4-week protocol for a patient with endometriosis associated with urinary incontinence. Case description: A 23-year-old female patient presented with chronic low back pain and also complained of difficulty in holding urine and leakage while doing forceful activities like lifting heavy objects, coughing, and sneezing in the past 6 months. She also complained of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Assessing the Impact of Chlorhexidine Mouthwash on Radiation-Induced Oral Mucositis in Head and Neck Cancer Patients: A Pre-Experimental Study
Abstract: Introduction: Cancer poses a major global health threat and is the second leading cause of death worldwide, following cardiovascular diseases, particularly in developed countries. Among cancers, head and neck cancer ranks as the 6th most common, representing about 6% of all cancer diagnoses. One of the frequent side effects of radiotherapy (RT) is mucositis, an inflammation of the mucous membranes. Chlorhexidine, a commonly used antiseptic and disinfectant found in mouthwashes, …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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Vocational Education in Higher Secondary Schools: A Review of Factors Influencing Student Interest and Attitudes
Abstract: The study investigates the essential aspects influencing students' motivation and attitudes toward vocational education in higher secondary schools, emphasizing its changing importance in current educational systems. Vocational education, which focuses on hands-on training and real-world applications, is critical in closing the gap between academic learning and the labor market. Despite its promise to promote employment, diversity, and economic development, vocational education faces considerable obstacles, such as societal stigma, insufficient resources, …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Air Pollution and Immune Disorders in Women from Urban Punjab: A Clinical and Epidemiological Study
Abstract: Background: Urban Punjab, particularly cities like Ludhiana, Amritsar, and Jalandhar, experiences some of the highest air pollution levels in India due to industrial activity, vehicular emissions, and agricultural practices. Despite this, gender-specific health impacts—especially related to immune function—remain inadequately studied. Objective of the study is to investigate the relationship between air pollution exposure and immune-related disorders in women residing in urban Punjab. A cross-sectional study was conducted from 2022 to …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 36–40 Read article
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Challenges in Diabetes Management Barriers and Support Systems in North India
Abstract: Background: The prevalence of Diabetes mellitus is ever growing in India and management of the disease is hindered by socio-economic, healthcare, and psychosocial barriers. Insofar as economic and social barriers pose challenges ranging from limited access to medical care, social stigma, specialist support leading to improper glycemic control, which is a strong predictor for diabetes complications, morbidity and mortality. Moreover, developing an understanding of systemic challenges and available supports is …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article