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599 articles for “genes” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Sliding Mode Controller-based Load Frequency Regulation for a Two-area Interrelated Power System
Abstract: This study presents the use of the sliding mode control approach for power systems load frequency regulation. A sliding mode load frequency controller is part of a two-area power system. Both reheat and non-reheat. These two regions each have a distribution of thermal turbines. Nonlinearities such as governor dead region and production rate limitations are included in the block diagram of a power plant model. Our control objective is to …
Published in International Journal of Advanced Control and System Engineering · Vol. 1, Issue 2, 2023 · pp. 8–13 Read article
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Exploring the Role of Ginkgo biloba in Investigating 7L1X in Triple-Negative Breast Cancer Through Integrative Bioinformatics
Abstract: Objectives: Triple-negative breast cancer is a very dangerous form of cancer that affects mostly Hispanic and African American women above the age of 40. It represents approximately 15–20% of the global cancer incidence. This experiment aims to investigate the use of Gingko biloba in the treatment of the disease triple-negative breast cancer. Methods: We use a variety of online tools, and websites, including the Indian Medicinal Plants, Phytochemistry, and Therapeutics …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 1–10 Read article
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Data-Driven Predictive Analytics and Decision- Making in FinTech Using MongoDB and High-Throughput Data Pipelines
Abstract: This paper examines the implementation of MongoDB and high-throughput data pipelines within the financial technology (FinTech) sector to drive data-informed predictive analytics and decision-making. The study focuses on the architectural components, scalability, and challenges of integrating NoSQL databases into real-time data ingestion and analytics pipelines. The transformative potential of these technologies in modern financial systems is highlighted through practical use cases such as fraud detection, credit scoring, and personalized financial …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 1, 2025 · pp. 1–15 Read article
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The Study of Preference on Skill-Based Training Among Household Women in Gudalur Town
Abstract: This study explores the need for skill-based training among women in households in Gudalur town, identifying preferred training types, choice-influencing factors, and participation barriers. Skill development is a critical component of women's empowerment, promoting financial autonomy and social mobility. Surveys were conducted with 50 women, who were chosen using a stratified random sampling method. The survey comprised demographics, most preferred training courses, perceived benefits, and participation barriers. Descriptive statistics was …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 Read article
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Empowering Vehicle: The Impact of Deep and Reinforcement Learning in IoV
Abstract: Deep learning and reinforcement learning represent two pivotal pillars within the realm of artificial intelligence and machine learning, bearing transformative potential in the domain of the Internet of Vehicles (IoV). This abstract explores the multifaceted applications of these cutting-edge techniques within the IoV framework. Deep learning, exemplified by convolution neural networks (CNNs) and recurrent neural networks (RNNs), empowers IoV systems with the prowess to discern complex patterns in sensory data. …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 3, Issue 2, 2025 · pp. 1–12 Read article
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Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Design, Mathematical Modeling, and Dynamic Optimization of a Speed Breaker-Based Vehicular Kinetic Energy Harvester
Abstract: Decentralized energy harvesting methods are becoming more popular due to rapid urbanization and the rising need for sustainable infrastructure. The road-embedded vehicle kinetic energy harvester (VKEH) design, mathematical modelling, and experimental validation are presented in this work. This paper presents the structural engineering, continuum mathematical modeling, and experimental validation of an optimized road-embedded vehicular kinetic energy harvester (VKEH). The mechanism utilizes a spring- loaded, low-friction rack-and-pinion transmission coupled with a …
Published in International Journal of Electrical Power and Machine Systems · Vol. 4, Issue 2, 2026 Read article
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Analysis of an Awareness Program of Cyber Security in PIET, Jaipur: A Systematic Survey
Abstract: This paper presents an analysis on what the students and the new generation think an out cyber security after learning about cyber-crimes and security in an awareness program. Our knowledge of technology has dramatically increased in the past five decades, as a result it also gave us a new type of threat, cyber-threats. Through smartphones and computers, life has become easy both for individuals and big organizations. Therefore, we must …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 1–9 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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A Narrative Review on Osteogenesis Imperfecta and Its Management
Abstract: Osteogenesis imperfecta (OI), sometimes referred to as brittle bone disease, is a heterogeneous illness characterized by short stature, several fractures, and distorted bones. The main contributing factor to OI is mutations in the genes needed to produce type 1 collagen. While severe OI is perinatally fatal, mild OI can occasionally not be detected until maturity. The frequency of Osteogenesis imperfecta ranges from about 1:15,000 to 1:20,000 births. Five kinds of …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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Preserving Saccharomyces cerevisiae Culture for Bee Health and Production
Abstract: Saccharomyces cerevisiae, a single-celled fungus also known as baker’s and brewer’s yeast, is extensively used in brewing, baking, and winemaking due to its robust genetics and utility as a model organism in scientific research. Its role extends beyond these applications into apiculture, where it is utilized to produce supplements and pollen replacements for honeybees. These yeast-based supplements are crucial, especially during times of pollen scarcity or colony stress, as they …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
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Municipal Material Management
Abstract: The increase in global prosperity and population has led to a significant rise in the generation of Municipal Solid Waste (MSW), posing serious threats to public health and the environment. This study explores the global state of MSW generation, composition, and management strategies, comparing the effectiveness of various technologies across 59 developed and developing countries. A total of 19 criteria for the selection of MSW management technologies are discussed, highlighting …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 11–15 Read article
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Innovative Approaches to Reducing Data Traffic in IoT Networks Using Deep Learning and Compressive Sensing
Abstract: The exponential growth of internet of things (IoT) devices has posed unprecedented challenges in managing the massive data generated by real-time monitoring, automation, and analytics. Existing network infrastructures lack scalability, bandwidth, and suffer from latency problems, further making data transmission less efficient. This study surveys innovative approaches using deep learning and compressive sensing to reduce IoT data traffic. Deep learning is able to upgrade data processing by means of very …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 46–62 Read article
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Reimagining Plastic Waste: The Impact of Eco-Bricking on Student Engagement and Community Sustainability
Abstract: Plastic pollution poses a severe threat to the environment, impacting ecosystems, wildlife, and human health. With millions of tons of plastic waste generated globally each year, innovative solutions for waste management are essential. This paper explores the eco-bricking initiative at Sovanagar High School, which transforms plastic waste into eco-bricks—sustainable building materials used for constructing green walls, benches, and other structures on the school campus. By effectively reducing plastic waste, this …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 23–25 Read article
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The Perpetuation of Psychological Wounds: A Comprehensive Review of Intergenerational Trauma in Indian Patriarchal Society
Abstract: The transmission of trauma effects from one generation to the next is known as intergenerational trauma, and it is particularly common in patriarchal civilisations such as India. Laws, economy, and social conventions are shaped by patriarchy, a societal framework that primarily gives males power, authority, and advantages. This perpetuates gender inequity and marginalises women. Aim: The purpose of this review is to examine how trauma is transmitted throughout generations in …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 20–26 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article