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189 articles for “ADME”
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Effectiveness of structured teaching programme on knowledge regarding Prophylactic vaccination against cervical cancer among adolescent girls
Abstract: Background: Adolescent health encompasses the variety of methods used to prevent, identify, or treat the health and wellness of young people. Adolescent health also includes the sexual and reproductive health of children and young adults. Women of all ages are susceptible to HPV infection. The human papillomavirus is the cause of cervical cancer . The HPV vaccine is an important main preventive measure against cervical cancer . Thus, it is …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Assessing the Socioeconomic Impacts of Land Tenure Systems Across Different Regions
Abstract: Land tenure systems are fundamental in shaping the socioeconomic structure and dynamics of communities across the globe. These systems, which define the legal and customary relationship between individuals, groups, and the land they own, use, or occupy, hold significant implications for economic development, social equity, and environmental sustainability. They determine how land resources are accessed, managed, and transferred, thereby influencing economic activities, wealth distribution, and community stability. This article provides …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 24–27 Read article
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Healthcare IT Innovations: Blockchain Technology for Healthcare Data Security and Privacy
Abstract: The healthcare sector has undergone a significant digital transformation, leading to the generation and sharing of vast quantities of sensitive medical data. While this digitization has improved patient care and outcomes, it has also introduced critical challenges related to data security and privacy. The increasing rate of data breaches in healthcare puts patient confidentiality at risk, mainly leading to identity theft, financial fraud, and loss of public trust in healthcare …
Published in International Journal of Information Security Engineering · Vol. 3, Issue 2, 2025 · pp. 01–12 Read article
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A Study on Mental Health, Psychological Support and Life Satisfaction For Tribal Community In Nilgiris-TN
Abstract: This research investigates the mental health challenges, psychological support systems, and overall life satisfaction among tribal communities in the Nilgiris district of Tamil Nadu. These indigenous groups, including the Todas, Kotas, Irulas, and Kurumbas, are undergoing significant social transitions due to modernization, environmental change, and cultural shifts: factors that increasingly influence their mental well-being. The primary objectives of this study are to assess the prevalence of mental health issues such …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 41–45 Read article
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The Relationship between Presentation of Online Self and Conscientiousness in Emerging Adults in India
Abstract: With the rise of social media use, understanding how individuals curate their online presence and experiment with different aspects of their digital identity is crucial in determining whether their online self is an extension of their offline identity or a distinct construct. This necessitates an examination of personality traits, particularly conscientiousness, to explore its role in online self-expression. Existing research suggests that individuals with high conscientiousness tend to maintain consistency …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 38–45 Read article
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Impact of Training Program on Recent Innovations in Oncology Among Nursing Professionals
Abstract: Introduction: In recent years, there have been significant advancements and trends in the field of oncology treatment in India. This study aimed to evaluate impact of training program on knowledge regarding recent innovations in oncology among nursing professionals. After ethical approval, a pre-experimental, one group pretest- post-test design was used to conduct this research at anursing college of Punjab. Methods: The sample was selected using the total enumerative sampling technique. …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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Prevalence and Risk Factors of Neglected Tropical Diseases Among Women and Children in Rural Liberia: A Regional Perspective
Abstract: Neglected Tropical Diseases (NTDs) remain a critical public health challenge in Liberia, disproportionately affecting women and children in rural regions due to systemic inequities in water, sanitation, and healthcare access. This cross-sectional study assessed the prevalence and risk factors of NTDs among 1,000 participants (600 children above 15 years and 400 women aged 15–49) in rural Liberia using stratified and cluster sampling. Laboratory diagnostics, including Kato-Katz stool analysis, urine filtration, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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e-learning Platforms in Higher Education: An Analysis of Institutional Planning, Implementation and Evaluation Strategies
Abstract: This quantitative study investigates the impact of e-learning platforms on student learning outcomes in higher education, focusing on institutional planning, implementation, and evaluation strategies. A descriptive-correlational research design was employed, surveying 100 administrators, faculty, and students from various higher education institutions. The results show significant positive correlations between platform organization, user-friendliness, instructor feedback, technical support, and student motivation. Well-structured platforms with clear communication of learning objectives, quality technical support, and …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 41–49 Read article
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A Study on Clinical Characteristics and The Impact Of Covid-19 In Hemodialysis Patients
Abstract: Background: The Corona Viruses Disease-19 pandemic has severely impacted Hemodialysis patients, who are vulnerable due to compromised immune systems and underlying comorbidities. Frequent Dialysis center visits increase their exposure risk to severe acute respiratory syndrome- Coronavirus Disease, and chronic inflammation, uremia, and immunosenescence may impair their immune response. Methods: This retrospective study included 60 Hemodialysis patients diagnosed with COVID-19 between January -July 2024. Data on demographics, clinical characteristics, laboratory results …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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ECO Report Analys Achieving SDG 15
Abstract: This project creates automated data processing tool Eco Data Analyser for ecological data analysis for SDG 15: Life on Land conservation and biodiversity. File_picker, Excel, and CSV are used in the Flutter and Dart based cross-platform solution to assist environmental organizations in handling ecological data. Uploading ecological datasets, verifying data, classifying biodiversity indicators, and producing summary reports helps Eco Data Analyser to make conservation data accessible and valuable. User-defined parameters …
Published in International Journal of Land · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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The Economic Impact of Land Acquisition for Industrial Projects
Abstract: Land acquisition for industrial projects plays a crucial role in promoting economic development, yet it often leads to significant socio-economic challenges. In India, land acquisition is regulated under the Right to Fair Compensation and Transparency in Land Acquisition, Rehabilitation and Resettlement Act, 2013. While this legislation aims to ensure fair compensation, transparency, and proper rehabilitation for affected individuals, its implementation often faces significant hurdles. Prolonged administrative delays, ongoing legal battles, …
Published in International Journal of Land · Vol. 2, Issue 2, 2025 · pp. 17–24 Read article
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An Experimental Study to Assess the Effectiveness of Self Efficacy on Academic Performance Among B.Sc. Nursing Students at Selected Colleges, Mangalore
Abstract: Self-efficacy refers to an individual's belief in their capacity to execute behaviors necessary to produce specific performance attainments. This study was conducted to evaluate the impact of self-efficacy on the academic performance of first-year B.Sc.Nursing students in selected colleges in Mangalore. The primary objective was to assess the relationship between self-efficacy levels and academic outcomes among these students. A quantitative research design was adopted for this study, with a sample …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 65–83 Read article
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A Comparative Study to Assess the Fetal Outcome Among Normal and Anemic Mothers at Sultania Zanana Hospital at Bhopal
Abstract: Anemia during pregnancy is a significant public health concern, especially in developing countries like India. It is a clinical condition characterized by a deficiency in hemoglobin levels, often due to inadequate intake of essential nutrients such as iron, folic acid, and vitamins. The World Health Organization classifies anemia during pregnancy as having hemoglobin levels under 11 g/dL, with specific thresholds varying by trimester. Maternal anemia not only affects the mother's …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 41–74 Read article
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Effectiveness of a Structured Teaching Programme on Knowledge and Attitude Regarding the Causes, Transmission, and Prevention of Sexually Transmitted Infections Among Rural Women in the Field Practice Area of RHTC, Yadwad, Dharwad District
Abstract: Sexually Transmitted Infections (STIs) pose serious long-term health risks, particularly for women and newborns. Women in rural areas often face significant social consequences due to inadequate STI awareness, which can lead to unsafe sexual practices. This study aimed to assess the knowledge and attitudes of rural women aged 15 to 49 years regarding the causes, transmission, and prevention of selected STIs in the RHTC Yadwad field practice area. Additionally, the …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 51–78 Read article