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1037 articles for “severity”
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Treatment of Hepatotoxicity
Abstract: An instantaneous or prolonged response to a synthetic or natural substance is known as drug-induced liver injury, or drug-induced hepatotoxicity (DILI). There are two distinct pathways that lead to hepatotoxicity: the more unpredictable idiosyncratic mechanism and the dose-dependent intrinsic mechanism. Several pathways, some known and others speculated, may be involved in the emergence of drug-induced damage. Drug-induced liver impairment can have several causes, and elevated liver tests are one of …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 31–37 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Unmasking Human Metapneumovirus: The Emerging Threat to Vulnerable Populations
Abstract: Human Metapneumovirus (HMPV) is a contagious respiratory virus that commonly spreads among individuals. It can cause serious infections, especially in high-risk groups like infants, older adults, and individuals with weakened immune systems.It is a major contributor to acute respiratory illnesses. Since its discovery in 2001, HMPV has been identified as a common cause of both upper and lower respiratory tract illnesses, with clinical presentations ranging from mild symptoms to severe …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 16–24 Read article
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Optimizing Sentiment Analysis with Naïve Bayes and Random Forest Techniques: A Result-based Approach
Abstract: In the increased digitalization, the sentiment analysis and classification have evolved as an eminent area to determine the polarity of positive, negative, and neutral reviews of the customers and users on products. It is an integral application field that employs supervised learning, Machine Learning, and Natural Language Processing concepts. The proposed Semantic Analysis and Classification using Naive Bayes and Random Forest system accomplishes the sentiment polarity by classifying the user …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 46–57 Read article
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A Study on Security Requirements of IOT
Abstract: In terms of speed, internet technologies have surpassed traditional technologies. Although the Internet's explosive growth has allowed it to reach its full potential, there are several security dangers associated with it. Many consumer-grade IoT devices are not designed with robust authentication protocols, making them easy targets for hackers. To address this, stronger multi-factor authentication (MFA) methods and certificate-based authentication should be implemented to ensure that only legitimate devices gain access …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 1, 2025 · pp. 24–28 Read article
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Unani Medicine Approaches To Liver Diseases :Therapeutic Principles and Review
Abstract: Background: For centuries, the Unani system of medicine has addressed liver diseases through principles that recommend specific therapies tailored to each ailment. Purpose: To analyze the therapeutic principles and Unani medications recorded for the treatment of liver diseases. Data Sources: Unani literary books in both Urdu and English were consulted, along with original e-research papers serving as databases. Limitation: This paper primarily focuses on the therapeutic principles related to liver …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 25–29 Read article
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Erythrodermic Psoriasis: A Case Report Highlighting Clinical Features and Management
Abstract: Background: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis that presents as widespread erythema, scaling, and systemic complications such as fever, dehydration, and electrolyte imbalances. It requires urgent medical attention due to the risk of life-threatening complications, including sepsis and multi-organ failure. The condition can arise de novo or as an exacerbation of pre-existing psoriasis, often triggered by medication withdrawal, infections, or systemic inflammation. Case Presentation: We …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 01–05 Read article
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Algorithm for the prediction of cardiovascular disease (CVD)
Abstract: cardiovascular diseases (CVD) still claim a significant number of deaths globally and remain the number one killer with an annual death toll of nearly 17.9 million. While several medical advancements have been made, an early diagnosis is still hard to obtain, which often leads to worsening conditions and intricate treatment options. With the advancement of modern technology, Machine learning has demonstrated to be a miraculous tool which can greatly impact …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Electromagnetic Transients in Compensated Overhead Lines with Multiple Tower Spans
Abstract: This paper addresses the analysis of the electromagnetic transients developed in an important class of non-uniform high-voltage power lines. It deals particularly with compensated long overhead high- voltage transmission lines composed of several tower spans, which are connected in cascade. The derived mathematical model leads to a system composed of simultaneous partial differential and algebraic equations, which can be solved numerically in terms of parametric functions using the software Mathematica’s …
Published in Trends in Electrical Engineering · Vol. 15, Issue 2, 2025 · pp. 1–9 Read article
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Cutting- Edge Gravitational-Wave Detectors: Technology & Innovations
Abstract: Gravitational wave detectors using laser interferometry are sophisticated instruments designed to measure the ripples in spacetime caused by cosmic events such as the merging of black holes or neutron stars. This schematic outlines the fundamental components and working principle of a typical laser interferometric gravitational wave detector, such as those used in the LIGO and Virgo observatories. The core of the detector is an interferometer, typically a Michelson interferometer, with …
Published in International Journal of Universe · Vol. 1, Issue 1, 2025 Read article
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IoT-Based Emergency SOS System for Post-Accident Assistance
Abstract: The increase in road accidents poses significant challenges for timely medical response, often leading to life-threatening delays. This project proposes an IoT-based accident wound detection system that utilizes a night vision camera mounted on either the interior or exterior of a vehicle. The system aims to detect injuries sustained by individuals during a collision and promptly alert emergency services. By employing a night vision camera, the system can operate effectively …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 2, 2025 · pp. 11–19 Read article
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Rodents and Zoonotic Diseases: Environmental Drivers and Prevention Measures
Abstract: Among the most ubiquitous animal species, rats spread several human diseases. Found in cities, rural areas, and everywhere in between, rats have adapted remarkably well to living alongside people. Unfortunately, this close contact makes it easier for them to carry and pass on harmful germs. Their biology, fast breeding, and ability to host various bacteria, viruses, and parasites often without getting sick themselves make them especially effective at spreading disease.This …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 12–21 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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An Efficient CNN Model for Automated Cotton Leaf
Abstract: Timely and accurate identification of cotton leaf diseases are essential for maintaining healthy crop production and minimizing agricultural losses. Early detection allows farmers to take preventive or corrective measures, reducing the risk of disease spread and improving overall yield. In this study, we propose a Convolutional Neural Network (CNN) based model for the automated classification of cotton leaf diseases using image-based detection techniques. The model is trained on a diverse …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 3, 2025 · pp. 01–10 Read article
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Post Halela Zard (Terminalia chebula Retz.): A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Halela Zard (Terminalia chebula Retz.), commonly known as Haritaki in Sanskrit and Chebulic Myrobalan in English, is a cornerstone of Unani pharmacotherapy due to its remarkable therapeutic versatility. The dried pericarp of its fruit has been extensively employed in traditional medicine for the treatment of a wide spectrum of ailments, ranging from digestive disturbances to chronic systemic disorders. This review aims to present a comprehensive overview of Halela Zard by …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 19–26 Read article
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Technometric Portrait of Sri Vinod Dham, an Indo-US Engineer, Father of Intel Pentium Process: A Quantitative Analysis
Abstract: Vinod Dham is recognized as the ‘Father of Pentium Chip’ or ‘Father of Intel Pentium Process’ in the field of the computer industry, and as an Indo-American pioneer from Silicon Valley. He has contributed 10 research papers during 1982–1986, with an average of two papers per year. This study tries to analyze his contributions through a bibliometric study and draw his familiarity as a world-famous electronic technologist. Data has been …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 16–25 Read article
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Analysis of the Impact of Seabed Earthquakes on Coastal Structures and Foundation Design
Abstract: Earthquakes in the seabed occur with varying magnitudes. Seabed earthquakes cause a rapid rise in water levels, which can lead to flooding and structural damage. Therefore, when designing buildings near the seashore, it is essential to account for the additional load on columns due to water thrust. Earthquakes occurring at the seabed generate intense ground acceleration of varying magnitudes, significantly affecting water levels and inducing destructive flooding along coastal regions. …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 42–49 Read article