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238 articles for “paradigm”
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Juncture of Nanotechnology and IoT: Novel Era of Connectivity
Abstract: The rapid development of Internet of Things(IoT) has had a profound impact on a variety of industries, enabling unprecedented levels of connectivity and data interchange between devices. Through the introduction of nanotechnology into IoT systems, there are unique prospects to improve performance, decrease energy consumption, and miniaturise components, which ultimately overlays the method for the progress of smart gadgets of the next generation. Through an analysis of significant developments in …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 3, 2025 Read article
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Enhancing Production Line Efficiency: Simulating and Optimizing Single and Parallel Line Processes
Abstract: During a time of fast-paced industrial growth, increasing production line effectiveness is a core issue for manufacturers looking to maximize output, reduce waste, and stay competitive. This study explores the use of simulation-based optimization methods to enhance single and parallel production line designs. Stepping beyond traditional trial-and-error methods, the research utilizes Siemens Tecnomatix Plant Simulation to simulate actual manufacturing scenarios, considering intricacies like buffer capacities, machine sequencing, and event-driven scheduling. …
Published in Journal of Production Research & Management · Vol. 15, Issue 1, 2025 · pp. 22–32 Read article
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KSK Approach: An AI-Driven IoT Based Decision Making System’s Study
Abstract: Internet of Things (IoT) has promised a world of interrelated devices, generating vast amounts of data. Traditionally, IoT systems trusted on preprogrammed procedures and human intervention to process data and make decisions. This approach often struggled to hold the sheer size and density of IoT data, leading to inefficiencies and missed opportunities. However, the true budding of that data lies not simply in its collection, but in its interpretation and …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 14–25 Read article
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Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article
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Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Advancements in Machine Learning: A Comprehensive Review of Algorithms, Applications, and Future Directions
Abstract: Gaining knowledge of Machine learning (ML)-guided format algorithms leverage predictive models to generate novel devices with optimized properties across several domains, which include drug discovery, fabric synthesis, and biomolecular engineering. Selecting an effective format set of policies consists of identifying appropriate hyperparameters, predictive models, and generative mechanisms to maximize format fulfilment. This study introduces an established method for set of policies requirements, ensuring that generated designs meet predefined fulfilment criteria, …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 17–33 Read article
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Advances in Polymer-Modified Concrete using XAI
Abstract: Industry 4.0 technologies are being quickly adopted by the construction sector, opening new avenues for enduring operational and environmental issues. This sector looks at how explainable AI can forecast air and enhance the quality of building materials. XAI, AI, ML, and big data drive a new paradigm in polymeric material development. The effective XAI and ML-assisted design creates innovative, high-performance polymeric materials. It covers building a database and representing structures, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 133–144 Read article
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Topology and Geometry in Data Science: Persistent Homology and Beyond
Abstract: In recent years, the interplay between topology, geometry, and data science has gained substantial momentum, offering powerful frameworks to analyze and interpret complex datasets. Traditional statistical and machine learning methods often rely on linear or metric- based assumptions, which may fail to capture the intrinsic structure of high-dimensional or nonlinear data. In contrast, topological and geometric methods provide shape-oriented, scale- invariant tools that focus on the continuity, connectivity, and global …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 21–27 Read article
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Evolution of Lean Manufacturing in Mechanical Industries: From Traditional Tools to Digital Transformation
Abstract: Lean manufacturing has long been a foundational strategy for enhancing productivity, reducing operational waste, and improving overall efficiency in mechanical industries. Initially developed as part of the Toyota Production System, lean principles focused on eliminating non-value-adding activities and streamlining processes using a set of well-established tools such as 5S, Kaizen, Kanban, and value-stream mapping. Over the decades, these principles have been adopted and refined globally, particularly within the mechanical sector, …
Published in Journal of Production Research & Management · Vol. 15, Issue 2, 2025 · pp. 13–18 Read article
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Comprehensive Review of Adenoid Cystic Carcinoma: Pathogenesis, Diagnosis, and Emerging Therapeutic Approaches
Abstract: Adenoid cystic carcinoma (ACC)is an infrequent neoplasm, highly malignant, that develops mainly in the salivary glands with the potential to exist in any secretory glandular sites, including the lacrimal glands, breast, and respiratory tract. ACC usually has a benign initial course, but conversely, it is notoriously aggressive in behavior with high incidence of perineural invasion, local recurrence, and distant metastasis, mostly to the lungs. The tumor’s molecular features are characterized …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 1–17 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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Comparative Performance Study: Deterministic vs. Probabilistic Models in Retail Chains
Abstract: The finished goods, raw materials, and product stock that a business has on hand for sale are referred to as inventory. They enable the companies to achieve their sales levels and are a chance to cost control and decision making. It is a huge asset to a manufacturing firm. Inventory model permits forecasting of quantities of raw material, inventory and spare parts of the equipment to a very high level …
Published in Recent Trends in Mathematics · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Adaptive E-Learning Algorithms and Heutagogy: A Systematic Analysis
Abstract: The proliferation of artificial intelligence (AI) and machine learning (ML) technologies has transformed the digital education landscape by enabling adaptive e-learning systems capable of personalizing content and optimizing learning paths. This study provides a systematic analysis of adaptive e-learning algorithms within the framework of heutagogy, an educational paradigm that emphasizes learner autonomy, self-direction, and capability development. The convergence of adaptive technologies with heutagogical principles offers new avenues for creating more …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 3, 2025 · pp. 33–38 Read article
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Evolution of Kinematic and Dynamic Design in Robotic Mechanisms: A Systematic Overview
Abstract: The field of robotics has experienced significant advancements in both kinematic and dynamic design, driven by the growing need for precision, adaptability, and autonomy in mechanical systems. Early robotic mechanisms were predominantly rigid and operated based on simple serial architectures, offering limited degrees of freedom and relying heavily on analytical formulations for motion planning and control. Over time, the demand for greater dexterity and operational versatility led to the development …
Published in Trends in Machine design · Vol. 12, Issue 2, 2025 · pp. 38–43 Read article
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Collaborative Care for Diabetic Retinopathy: Integrating Artificial Intelligence and Clinical Pharmacy Services - A Comprehensive Review
Abstract: Background: Diabetic retinopathy (DR) remains the leading cause of blindness among working-age adults globally, affecting approximately 103 million people worldwide. The integration of artificial intelligence (AI) technologies with clinical pharmacy services presents unprecedented opportunities to enhance screening, diagnosis, and management of DR through collaborative care models. Objective: This comprehensive review examines the current landscape of collaborative care approaches for diabetic retinopathy management, focusing on the integration of AI-powered diagnostic tools …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 118–128 Read article
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AI-Enhanced Interpretation of Cardiac Troponins: Toward Predictive Precision in Myocardial Injury
Abstract: Background: Cardiac troponins (cTn) represent the gold standard biomarkers for myocardial injury detection, yet their interpretation remains challenging due to various confounding factors and clinical contexts. Artificial intelligence (AI) technologies provide remarkable possibilities to improve the interpretation of troponin levels by utilizing pattern recognition, predictive modeling, and clinical decision-making support. Objective: This review examines the current state and future potential of AI-enhanced cardiac troponin interpretation, focusing on machine learning applications, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–9 Read article
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From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Investigation On Waste Management And Its Recycling
Abstract: For doing the inventions with the Green Initiatives recycling and reusing of products is very essential. It has been acknowledged that one of the most important elements in achieving growth, environmental sustainability, and improved quality of life is green product innovation. Theory and practice have made it a strategic priority to comprehend how innovation and sustainability combine to produce green product innovation. In the face of growing environmental concerns and …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 2, 2025 · pp. 51–60 Read article