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312 articles for “optimal path”
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AI-Enabled Optimization of Additively Manufactured Composite Materials for Enhanced Mechanical and Thermal Performance
Abstract: This paper discusses the optimization of multi-objective optimization of enhanced coupling of heat and mechanical properties of 3D printed polymer composite materials by artificial intelligence (AI), as a component of a multi-objective optimization framework. It aims at development of nonlinear printing parameters and material properties relationships to achieve maximum tensile strength and thermal conductivity in polymer composites produced through fused deposition modeling (FDM). Short carbon fiber reinforcement was used to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 867–891 Read article
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Optimizing Manufacturing Processes with Taguchi Method in Production Engineering
Abstract: The Taguchi Method, pioneered by Genichi Taguchi, stands as a powerful optimization tool within the realm of production engineering. This paper delves into the principles, applications, and significance of the Taguchi Method in enhancing manufacturing processes. With a focus on minimizing variation and improving performance, this methodology plays a crucial role in addressing challenges faced by industries in their pursuit of operational excellence. The core components of the Taguchi Method, …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Solar Light Photocatalytic Degradation of Methylene Blue and Methyl Orange Dyes by Ag-ZnO Nanocomposite
Abstract: A highly efficient silver-assisted ZnO nanocomposite was synthesized using the co-precipitation method, a technique that ensures a controlled and homogeneous formation of the composite material. The high purity of the synthesized nanocomposite was confirmed through detailed FTIR spectra analysis, which showed clear and distinct peaks corresponding to the functional groups present, indicating the absence of significant impurities. To evaluate the photocatalytic capabilities of the nanocomposite, a series of tests were …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 160–171 Read article
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AI-Driven Multi-Objective Optimization of Conductive Polymer Composites for High-Performance Flexible Electronics
Abstract: The development of conductive polymer composites (CPCs) is critical for advancing flexible and wearable electronic technologies. However, the conventional trial-and-error approach to material formulation is time-consuming and often inefficient due to the high-dimensional nature of the design space. This study introduces a novel AI-driven framework that integrates machine learning (ML) with multi-objective optimization to accelerate the discovery of high-performance CPCs. A dataset of 1,000 experimentally reported formulations was compiled, capturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 734–745 Read article
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Pathways in Drug Discovery and Development: From Molecular Targets to Market Approval
Abstract: A complicated, multidisciplinary, and resource-intensive process, the discovery and development of new pharmacological drugs is essential to the advancement of contemporary medicine. Finding and optimising lead chemicals comes after a disease-relevant biological target has been identified and validated. Through preclinical research in animal models, these leads are thoroughly assessed for toxicity, pharmacokinetics, safety, and efficacy. Clinical trials, which are carried out in several stages to evaluate safety, efficacy, ideal dosage, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 01–04 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 41–49 Read article
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An Overview of 98 Cases of Idiopathic Granulomatous Mastitis
Abstract: Background: Granulomatous mastitis is an uncommon, benign, chronic inflammatory condition of breast of uncertain etiology. The clinical features mimic tuberculosis and breast cancer that leads to diagnostic and therapeutic dilemma. Its optimal management is still unclear with high recurrence rate. Purpose: The purpose of this study is to present the clinico-pathological features of patients with Granulomatous mastitis and our experience with the medical and surgical treatment of these patients. Methods: …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 1, 2018 · pp. 5–9 Read article
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Electrically Conductive Micro-Aluminum Reinforced Polymer Composites for IoT-Enabled Lightweight Antenna Housings
Abstract: Electrically conductive polymer composites have emerged as promising multifunctional materials for lightweight antenna housings by integrating structural strength, electrical conductivity, thermal stability, and electromagnetic interference shielding. In this study, micro-aluminum reinforced Acrylonitrile Butadiene Styrene (ABS) polymer composites were fabricated using twin-screw melt compounding followed by compression molding for IoT-enabled lightweight antenna housing applications. The influence of micro-aluminum loading on microstructure, mechanical performance, electrical conductivity, EMI shielding, thermal stability, and wireless …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Mucosal Vaccines in Fish: Novel Advances in Technology and Delivery: A Review
Abstract: Vaccines rely on the acquired immune system and prime an animal to a particular antigen so that on subsequent encounter; it is recognized and quickly destroyed. The vast majority of pathogens enter the body via the mucosal surfaces of the gastrointestinal, respiratory, and urogenital tracts, where they initiate mucosal infections that lead to systemic infections. There is strong evidence that an optimum mucosal immune response can prevent systemic infection and …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 14–26 Read article
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Analysis of Project Management Optimization Using CPM and PERT in a Dynamic Business Environment
Abstract: In the current fast-changing business environment, organizations must remain agile and strategically responsive to unpredictable challenges such as supply chain disruptions, shifting consumer demands, and evolving market trends. Project management techniques like the Critical Path Method (CPM) and the Program Evaluation and Review Technique (PERT) serve as valuable tools in helping businesses manage these complexities effectively. CPM is a time-focused method that identifies the longest sequence of dependent tasks in …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 Read article
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Tailoring The Electrochemical Interface of Graphene–Gd₂O₃ Nanocomposites for Advanced Energy Storage
Abstract: Graphene–Gd₂O₃ nanocomposites were synthesized by incorporating varying concentrations of reduced graphene oxide (rGO) into Gd₂O₃ using a straightforward room-temperature solution method. The composites were analyzed using various distinct characterization techniques, including X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). Electrochemical measurements, particularly cyclic voltammetry (CV), demonstrated that the incorporation of graphene significantly enhanced the electrochemical performance …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 369–388 Read article
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Experimental Analysis and Predictive Modeling of Mechanical Behavior in Epoxy Composites Reinforced with Waste Tyre Rubber Particles
Abstract: The disposal of end-of-life tyres poses a significant environmental and resource challenge owing to their large volumes and non-biodegradable nature. In this work, we explore the incorporation of waste tyre rubber particles (WTRP) into an epoxy resin matrix to develop sustainable polymer composites and examine their mechanical behavior both experimentally and through predictive modelling. Composites with differing epoxy: WTRP ratios (80:20, 75:25, 70:30 wt.%) and varying rubber particle mesh sizes …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1754–1765 Read article
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Advancing Conductive Ink Formulations for DIW with Graphene and Hybrid Nanostructures
Abstract: The development of solvent-based conductive inks for direct ink writing (DIW) has gained significant attention as a pathway toward flexible, wearable, and scalable electronic devices. This review critically examines conductive fillers, binders, solvent systems, and hybrid ink strategies reported in recent literature. Graphene and carbon nanotubes (CNTs) remain the most studied fillers due to their high intrinsic conductivity and unique dimensionality, but challenges such as restacking, bundling, and high viscosity …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 3, 2025 · pp. 36–49 Read article
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Enhancing Compressive Strength of M25 Grade Concrete Using Ceramic Tiles Waste and Waste Fiber Metal: A Path Toward Sustainable Construction
Abstract: This study explores the use of Ceramic Tiles Waste and Waste Fiber Metal as partial replacements in M25 grade concrete, focusing on their impact on compressive strength. Various combinations of waste materials were tested to determine the optimal mix proportions. Compressive strength tests were conducted on concrete cubes incorporating 0.30%, 0.40%, and 0.50% Waste Fiber Metal with varying percentages of Ceramic Tiles Waste ranging from 20% to 50%. The results …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 13–19 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Development of an Open Source Modular Control System for Articulated Robotic Arm
Abstract: An open source modular control system architecture consist of different control modules for motion control, path planning, sensory feedback etc. which all can be extremely beneficial to develop an integrated control system for an articulated robotic arm. In this proposed work, different open source robot control software was being identified and an optimized modular robot control system was developed for controlling the articulated robotic arm. The control system was being …
Published in Journal of Advancements in Robotics · Vol. 3, Issue 2, 2016 · pp. 1–9 Read article
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AI-Driven Prediction of Square-Hole Laser Trepanning Performance in AA7075/15%SiC/15% Glass Fiber Hybrid Composites Using Taguchi–ANOVA and Deep Neural Networks
Abstract: Hybrid AA7075 composites reinforced with 15% silicon carbide (SiC) and 15% glass fiber were fabricated via the stir casting technique to improve machining and structural performance. The addition of dual reinforcements into the aluminum matrix was aimed at enhancing hardness, thermal stability, and surface quality during non-traditional drilling operations. Square-hole drilling was performed using a laser trepanning process, and the key responses—hole size accuracy, surface roughness, and taper angle—were systematically …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1932–1943 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article