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143 articles for “method development and validation”
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From Baseline Survey to Management Plan: A Systematic Framework for Port-Specific Mitigation of Underwater Radiated Noise
Abstract: The growing recognition of underwater radiated noise (URN) as a significant marine pollutant necessitates the development of actionable management frameworks at the port level, where noise sources are concentrated, and impacts can be particularly acute. While international guidelines exist, a standardized methodology for ports to transition from assessment to implementation is lacking, particularly in regions with high biodiversity and developing maritime infrastructure. This paper presents and demonstrates a systematic, four-phase …
Published in Journal of Offshore Structure and Technology · Vol. 13, Issue 1, 2026 · pp. 22–30 Read article
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The Awareness–Behaviour Paradox: Media Literacy and Social Media Risk Behaviour Among Nigerian Undergraduates
Abstract: Background: The proliferation of internet-capable devices and social media platforms has created an intricate web of risks for Nigerian undergraduates, including cyberbullying, addiction, misinformation, and exposure to indecent content. While media literacy has been widely proposed in Western scholarship as a sustainable intervention for responsible online behaviour, its protective mechanisms remain insufficiently understood in non-Western contexts, particularly with respect to the psychological pathways through which literacy operates. Objectives: This study …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 121–126 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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A Study to Evaluate the Effectiveness of Sensory Stimulation Program (SSP) on Motor Function (MF) and Verbal Response (VR) Among Patients with Stroke in ICU of Selected Hospitals at Salem
Abstract: Introduction: Stroke is a medical emergency and can cause permanent neurological damage, complications and death. Objectives: (1)To develop and validate a Sensory Stimulation Program aimed at enhancing motor function (M.F) and vital signs recovery (V.R) in stroke patients. (2)To evaluate and compare the pre-test and post-test scores of M.F and V.R in stroke patients receiving routine nursing care. (3)To assess and compare the pre-test and post-test scores of M.F and …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 16–28 Read article
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Review of Research on Pozzolanic Materials for Cement Blending and Concrete Applications
Abstract: The growing environmental concerns associated with cement production, particularly its high carbon footprint, have driven research into sustainable alternatives such as supplementary cementitious materials (SCMs) derived from agricultural and industrial waste. This study synthesizes findings from recent investigations into the pozzolanic potential of basil plant ash (BPA), rice husk ash (RHA), and stockpiled fly ash (FA), evaluating their processing methods, microstructural characteristics, and performance in concrete applications. BPA, being derived …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 1–6 Read article
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Quantitative Research on Gen Z Slang Terms for a Diverse Group of People
Abstract: This study objective is to determine the various individuals who employed vocabulary connected with Generation Z and to discover who those persons were. Through the use of Google forms, twenty Gen Z slang terms associated were posed to the various participants for testing. The data are collected from the participants by the researcher through the use of Google Forms, and the researcher is the one who is responsible for developing …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 24–31 Read article
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Machine Learning Framework for Optimizing Polymer–Metal Oxide Composites as Charge Selective Layers in Perovskite Solar Cells
Abstract: To achieve high-performance and stability of perovskite solar cells (PSCs), it was important to incorporate innovative interfacial materials to tune the balanced charge extraction, low recombination, and enhanced operational lifespan. On this note, polymer composites with metal oxides have been proposed as promising candidates as charge selective layers (CSLs), whereby they present a rare combination of tunable energy levels, improved film forming abilities, and better interface engineering capabilities. In this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1073–1098 Read article
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Emotion Recognition from Electroencephalogram Signal and Eye Movement Based on Deep Learning
Abstract: Emotion recognition from electroencephalogram (EEG) signals has gained significant attention due to its potential in human- computer interaction (HCI), mental health monitoring, and personalized content delivery. This paper presents the use of Convolutional neural networks (CNNs) to classify emotions such as happiness, sadness, fear, neutral, and disgust by leveraging a fusion of EEG signals and eye movements data. Compared to conventional methods of emotion detection, such as those that rely …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 8–15 Read article
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Innovative Approaches to Reactive Power Management and Optimization in Modern Power systems
Abstract: Reactive power management and optimization are necessary for the effective, stable, and reliable working of modern power systems. Without proper management, reactive power is responsible for additional losses in transmission, reduced capability of power transfer, and poor voltage stability conditions, thus forming a basis for developing advanced techniques of optimization. This paper discusses the innovative methods in Reactive Power Optimization (RPO) using met heuristic algorithms, namely the Self-Balanced Differential Evolution …
Published in Journal of Power Electronics and Power Systems · Vol. 15, Issue 3, 2025 · pp. 44–50 Read article
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Artificial Neural Network Modelling to Optimize Micro-Drilling Parameters of ECDM of Developed Novel Zn/(Ag+Fe)-MMC
Abstract: Several engineering fields have increased their use of metal matrix composites (MMCs) in the past few years. Due to the increase in composites, the demand for accurate machining has also become important. Specifically, pertaining to biomaterial applications, accuracy factor with desired surface finish is critical. While the near-net shape manufacturing process has advanced, MMCs frequently require post-mould machining to achieve surface quality, and dimensional tolerances. In the present study, a …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 01–13 Read article
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Generative AI-Based Inverse Design of Sustainable Biodegradable Polymers with Target Mechanical and Thermal Properties
Abstract: The escalating global plastic pollution crisis has intensified the urgent need for sustainable biodegradable polymer alternatives that can match or exceed the performance of conventional petroleum-based plastics while minimizing environmental impact. However, traditional polymer discovery approaches are severely constrained by high experimental costs, protracted development cycles spanning years, and fundamental inability to simultaneously optimize multiple conflicting material properties such as mechanical strength, thermal stability, and degradation kinetics. This study presents …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Machine Learning-Assisted Design and Optimization of Lightweight Polymer Composites for IoT-Enabled Automotive Applications
Abstract: This study aims to develop an integrated machine learning and optimization framework for the intelligent design of lightweight polymer composites suited for IoT-enabled automotive applications. The goal is to enhance material performance while satisfying multiple design constraints such as mechanical strength, thermal stability, and process compatibility. A curated dataset of polymer composite formulations was used to train a Random Forest Regression (RFR) model capable of predicting tensile strength, thermal conductivity, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 12–27 Read article
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Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Optimizing Power Generation from Building Ventilation Systems: A Study on Exhaust Fan Efficiency
Abstract: Due to population growth, the world's energy consumption has increased dramatically in both wealthy and developing nations in recent years, and by 2042, it is predicted to have doubled or more. Since a few years ago, the use of innovative sustainable power sources to meet energy demands has been gradually increasing. We've chipped away at a different idea because of this. As an alternative energy source, renewable energy (RE) resources …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 22–27 Read article
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Design and Manufacturing of Suspension and Steering System of a F3 Vehicle
Abstract: The suspension and steering systems are critical subsystems of any formula-style racing vehicle, directly influencing its stability, handling, and driver safety. This paper focuses on the design, analysis, and manufacturing of suspension and steering systems for a Formula Student F3 vehicle. The primary objective is to develop a lightweight, reliable, and efficient design that complies with Formula Student competition rulebooks while ensuring optimum ride quality and performance. Using advanced computer-aided …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article