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134 articles for “data profiling”
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Gear-Related Stress Analysis and Comparison Between the Fem and Agma Standards
Abstract: In many different devices, gears enable the efficient transfer of motion and torque. They are an essential component of modern mechanical power transmission systems. It has been demonstrated that bending and surface contact stresses at the gear tooth are the primary causes of gear failure, despite their widespread use. Too much stress can lead to tooth wear, pitting, or breakage, which can ultimately reduce the operating life and reliability of …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 13–18 Read article
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Webometric Indicators and Digital Impact: An Evaluation of Top Ten NIRF-Ranked Indian University Websites
Abstract: This paper compares the webometric performance and digital presence of the top ten NIRF 2025–ranked Indian universities through their official websites. Data regarding total links (internal and external), Google-indexed links, URLs, and the Web Impact Factor (WIF) were gathered and analyzed using Google as the main search engine. The data collection and interpretation are based on the use of link analysis tools and search engine optimization (SEO) techniques. The analysis …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 1, 2026 · pp. 1–9 Read article
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Damage Evolution and Delamination Resistance in Polymer Matrix Functionally Graded Laminates
Abstract: Functionally graded laminates (FGLs) in polymer-matrix systems represent a promising pathway to enhance damage tolerance and delay delamination in advanced structural composites. In this study, we explore the mechanisms of damage initiation, propagation, and delamination resistance in polymer matrix functionally graded laminates (PM-FGLs) through a combined experimental–computational approach. Laminates with linear, exponential, and bio-inspired gradation profiles were fabricated using vacuum-assisted resin transfer molding (VARTM) and additive manufacturing techniques. Comprehensive mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 321–337 Read article
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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Thermo-Fluid Characterization of Corrugated U-Tube Shell-and-Tube Heat Exchanger with Polymer Composite Tube Wall: A Combined CFD and Experimental Investigation
Abstract: Shell-and-tube heat exchangers built with metallic tubes work well thermally, but corrosion problems, extra weight, and the inability to adjust the wall’s thermal properties through material choice remain genuine engineering headaches, particularly for corrosive or weight-critical applications. Over the past few years there has been a fair amount of interest in replacing metal tubes with polymer composite alternatives, since blending thermally conductive fillers — graphite nanoplatelets, boron nitride platelets and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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History, Processing, Types and Health Benefits of Indian Yogurt
Abstract: Yogurt is a food which is nutrient rich and it is produced after the milk bacterial fermentation. Yogurt should have 3.25% milk fat and 8.25% milk solids non fat and the titrable acidity of at least 0.9%, which is expressed as lactic acid. Before adding bulky flavoring additives, the USDA yogurt criteria specify that the yogurt must satisfy the composition requirements of milk fat and MSNF. The data used in …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Aura Pulse: An AI-Powered System for Real-Time Emotional Support and Personalized Recommendations
Abstract: Aura Pulse is a cutting-edge AI-powered platform developed to provide real-time emotional support, tackling the growing challenges of stress, anxiety, and burnout in today’s fast-moving digital era. Utilizing advanced facial expression analysis, Aura Pulse interprets visual cues to create a comprehensive emotional profile of the user. This instant emotional evaluation enables the platform to deliver personalized suggestions aligned with the user’s mood and mental state, promoting overall well- being and …
Published in Journal of Advancements in Robotics · Vol. 13, Issue 1, 2026 · pp. 18–25 Read article
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Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
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Leveraging Standards and Deep Learning Approaches to Secure Internet of Things (IoT) Devices from Cyber Attack
Abstract: The widespread adoption of Internet of Things (IoT) devices between 2019 and 2024 has significantly grows in various sectors in Japan, including healthcare, manufacturing, and the development of smart cities. Although this growth offers many advantages, it also makes these devices more vulnerable to cyber threats. High-profile security breaches in Japan have sparked discussions about the requirement for enhanced security measures to protect the rapidly evolving IoT technologies. This study …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 1, 2025 Read article
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Immunological and Genetic Markers of Rheumatoid Arthritis Among Women in North India: A Case-Control Study
Abstract: Background: Rheumatoid arthritis (RA) is an autoimmune disease systemically afflicting women marked by chronic inflammation around the involved joints leading to joints destruction. It has both endocrinological and immunological associations as well as genetic associations but data pertaining to women of North India is scanty. Objective: This case-control study was done to evaluate the presence and significance of major immunological and genetic markers of RA in North Indian women with …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article