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143 articles for “method development and validation”
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Secured Communication and Image Authentication: Embedding Encrypted Text Files Into Color Digital Images
Abstract: In today's digital landscape, protecting digital assets, particularly images, is paramount. Researchers have developed various techniques to safeguard these assets, emphasizing their protection and integrity. Simultaneously, steganography plays a crucial role in securely communicating confidential messages. This paper focuses on a dual-purpose technique: watermarking color digital images for protection and embedding secret messages through steganography. This fusion of functionalities represents a significant step in comprehensive asset protection and confidential communication …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 10–15 Read article
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A Comprehensive Review on the Miniaturized Analytical Techniques for Sustainable Pharmaceutical Testing
Abstract: Miniaturized analytical techniques are revolutionizing pharmaceutical testing by offering sustainable and efficient alternatives to traditional methods. These techniques are designed to reduce sample and reagent consumption, minimize waste generation, and accelerate analysis, aligning perfectly with the principles of green analytical chemistry. This comprehensive review aims to thoroughly explore the landscape of miniaturized analytical techniques, specifically highlighting their profound impact on fostering sustainable practices within the pharmaceutical sector. The review systematically …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 18–39 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Structural Optimization of FDM-Processed ASA Polymer Frames through Acetone Solvent Welding, Variable Infill Strategy, and Layer Orientation: Experimental Validation via Quadcopter Flight Testing
Abstract: Acrylonitrile styrene acrylate (ASA) is an amorphous terpolymer with superior UV resistance compared to acrylonitrile butadiene styrene (ABS), as its acrylate rubber phase lacks photodegradation-prone carbon–carbon double bonds. This study proposes acetone solvent welding as a polymer joining method to produce monolithic structures from FDM-processed ASA components, addressing three processing challenges: achieving structural continuity through polymer chain interdiffusion at solvent-wetted interfaces, correcting thermal warping via post-print geometric correction during welding, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 689–703 Read article
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The Impact of Food Fortification on Health and Nutrition
Abstract: This comprehensive study explores the critical role that food fortification plays in enhancing nutritional outcomes and overall health. Through an extensive review of existing literature, this article explores the diverse ways in which fortifying foods with essential nutrients positively influences public health. This analysis encompasses the benefits of fortification by addressing micronutrient deficiencies, promoting overall well-being, and preventing various health conditions. Food fortification is a pivotal intervention in the realm …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Analyzing the Role of Fiber Composition in Drying Behavior: A Comparative and Predictive Approach
Abstract: This research presents a comprehensive analysis of the drying behavior and thermal response of three distinct fabric types: 100% Cotton, 100% Polyester, and a Polyester blend (65/35), under meticulously controlled environmental conditions. The Polyester blend (65/35) consists of 65% Polyester and 35% Cotton, combining characteristics of both fibers. The investigation focuses on understanding how fiber composition impacts drying time, moisture retention, and thermal characteristics. Experimental trials were conducted using standardized …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 1–11 Read article
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Design and Development of Lightweight Polymer Composite Manifold Using CF-ABS and GFRP for Aerodynamic Energy Recovery in Electric Vehicles
Abstract: Electric vehicles provide a number of advantages over conventional fuel vehicles due to their low to no emissions. High energy efficiency improves the driving performance of Electric vehicles. However, they have to face certain challenges such as the high purchase cost of batteries and lack of battery charging facilities. The major drawback of an Electric vehicle is to store sufficient energy to run the vehicle for a long time. This …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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Development and Performance Evaluation of Hybrid Solar Water Heating and Distillation Systems for Sustainable Water Supply: A Comprehensive Review
Abstract: This review article delves into the comprehensive examination of hybrid solar water heating and distillation systems, underscoring their pivotal role in addressing global water and energy challenges. With the increasing scarcity of clean water and the growing demand for sustainable energy solutions, these hybrid systems offer a promising dual-purpose approach. The article synthesizes the latest advancements in technology, design methodologies, and performance evaluation metrics, providing a holistic view of the …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 1, 2024 · pp. 8–19 Read article
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Thermo-Mechanical and Electrical Properties of Multi-Walled Carbon Nanotube-Enhanced Polyimide Composites for Aerospace Thermal Protection Systems
Abstract: Advanced aerospace thermal protection systems (TPS) require multifunctional materials that simultaneously provide high thermal stability, mechanical strength, and reliable electrical performance. Polyimide (PI) is widely used in aerospace structures due to its lightweight design and exceptional thermal durability, yet its low thermal conductivity and insulating behavior limit its effectiveness in heat dissipation and electromagnetic interference (EMI) shielding applications. This study addresses these limitations by developing multi-walled carbon nanotube (MWCNT)-reinforced polyimide …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 966–982 Read article
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Smart Monitoring and Controlling of the Battery and Motor
Abstract: The demand for effective battery and motor monitoring and management to guarantee dependability, safety, and peak performance has increased due to the quick development of electric vehicles and smart industrial systems. The smart monitoring and control methods used in battery management systems and motor control systems are thoroughly reviewed in this paper. In addition to speed, torque, efficiency, and fault situations in motors, it emphasizes important characteristics like temperature, voltage, …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 4, Issue 1, 2026 · pp. 11–15 Read article
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An Observational Study on Prevalence and Risk Factors for OA Knee Joint Among Adult Population Attending the SCSP Camps in Chennai, Tamil Nadu, India
Abstract: Background: Osteoarthritis (OA) is a prevalent degenerative condition affecting older individuals, particularly in developing nations. It is commonly linked to aging and various intricate underlying causes. The complex causes of osteoarthritis include confounding factors that significantly increase the risk of its development, many of which can be managed or prevented. Among all joints, knee osteoarthritis is particularly prevalent, especially in women. In rural India, the SC/ST population faces significant health …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 9–17 Read article
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Improvement of Geometric Tolerances and Mechanical Properties of Aluminum Hybrid Metal Matrix Composites
Abstract: In the field of metal matrix composite materials, there has been a generous thrust towards the development of electrical discharge machining (EDM). In this study, stir casted aluminum hybrid metal matrix composites were successfully machined using EDM by analyzing the input process parameters namely, pulse-on time, peak current, and gap voltage using L27 orthogonal array. The ideal conditions for various output responses such as material removal rate, circularity, and radial …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1583–1592 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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DC Motor Speed Control Using Arduino & L298N Motor Driver
Abstract: The focus of this project is on developing a DC motor speed controller using an Arduino microcontroller and an L298N motor driver module. The goal is to create a flexible and effective system that can control the speed, direction of a DC motor through PWM signals generated by the Arduino. The project utilizes the Arduino platform for its flexibility, ease of programming, and wide availability of resources, while the L298N …
Published in Journal of Mechatronics and Automation · Vol. 11, Issue 3, 2024 · pp. 1–7 Read article
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Hybrid Additive-Subtractive Manufacturing of Multi-Material Functionally Graded Components: Integration of Laser Powder Bed Fusion with High-Speed CNC Finishing for Aerospace Applications
Abstract: The synergy involved in the merging of additive and subtractive manufacturing technologies is the game changer to generate multi-material functionally graded components to be used in the aerospace industries. The paper is an in-depth review of a proposed hybrid additive-subtractive manufacturing, which synergistically merges laser powder bed fusion (LPBF) fashioning with rapid computer numerical control finishing production processes. The multi-material deposition, thermal issues, and optimization of post-processing are the challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 398–418 Read article
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Application of Artificial Neural Networks in Optimizing Polyhouse Roof Truss Design
Abstract: Polyhouses are specialised agricultural structures developed to maintain controlled environmental conditions for crop cultivation, thereby ensuring consistent productivity even under adverse climatic circumstances. The performance of these systems largely relies on the structural stability and cost efficiency of the roof truss, which must achieve an effective balance between strength, adaptability, and economy. In this research, an Artificial Neural Network (ANN)-based modelling framework is introduced to optimise the members of polyhouse …
Published in Recent Trends in Civil Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 15–25 Read article
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Development and Mechanical Characterization of Polymer based Bio Composite Filaments for FDM Applications
Abstract: Additive Manufacturing (AM) is an advanced fabrication process capable of producing complex and intricate components to meet diverse industrial and customer demands. For small-scale producers and researchers, FDM is the most straightforward, affordable, and easily accessible of the several AM processes. The majority of conventional polymer feedstocks used in FDM lack sufficient mechanical strength and thermal stability, which limits their use in load-bearing or structural components. This effort aims to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 743–751 Read article
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Optimizing Mechanical and Durability Properties of Eco-Friendly Composite Materials Using Recycled Fillers and ML Techniques
Abstract: The increasing demand for sustainable construction materials has intensified the exploration of recycled fillers as partial or full replacements for natural aggregates in composite materials. This study investigates the mechanical and durability performance of polymer matrix composites incorporating processed recycled fillers derived from construction and demolition (C&D) waste. Three distinct processing methods were employed to prepare the recycled fillers: untreated (URF), single processed (SPRF), and double processed (DPRF), with replacement …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 269–309 Read article
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Design and Research of Thermoelectric Energy Harvesting Methods for Instantaneous Use
Abstract: In today’s consumer-oriented market, researchers are attempting to harness energy from ambient sources for sustainable energy generation leading to reduction of dependency on conventional energy sources. Energy harvesting methods offers enormous opportunities to derive energy from our natural surroundings to directly operate self-powered devices or storing it for later use. Generating energy from our nearby environment seems to be a promising solution to address the growing concerns of powering small …
Published in Trends in Machine design · Vol. 13, Issue 1, 2026 · pp. 1–16 Read article